Detalhe da pesquisa
1.
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.
Cell
; 161(6): 1252-65, 2015 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26046436
2.
Characterization of Glucokinases from Pathogenic Free-Living Amoebae.
Antimicrob Agents Chemother
; 66(6): e0237321, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35604214
3.
Dihydropyrazinoquinazolinones via SN2 Sulfamidate Ring-Opening and a Sequential Quinazolinone-Amidine Rearrangement Strategy (SQuAReS).
J Org Chem
; 87(21): 14889-14898, 2022 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36194836
4.
Emergence and Magnitude of ML336 Resistance in Venezuelan Equine Encephalitis Virus Depend on the Microenvironment.
J Virol
; 94(22)2020 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32878897
5.
Construction of N-Boc-2-Alkylaminoquinazolin-4(3H)-Ones via a Three-Component, One-Pot Protocol Mediated by Copper(II) Chloride that Spares Enantiomeric Purity.
Adv Synth Catal
; 363(6): 1638-1645, 2021 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33867902
6.
Divergent 2-Chloroquinazolin-4(3H)-one Rearrangement: Twisted-Cyclic Guanidine Formation or Ring-Fused N-Acylguanidines via a Domino Process.
Chemistry
; 26(11): 2486-2492, 2020 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31912567
7.
Synthesis of Ring-Fused, N-Substituted 4-Quinolinones Using pKa-Guided, Base-Promoted Annulations with Isatoic Anhydrides: Total Synthesis of Penicinotam.
J Org Chem
; 85(2): 464-481, 2020 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31786917
8.
Enzymatic and Structural Characterization of the Naegleria fowleri Glucokinase.
Antimicrob Agents Chemother
; 63(5)2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30783001
9.
Telescoped synthesis of C3-functionalized (E)-arylamidines using Ugi-Mumm and regiospecific quinazolinone rearrangements.
Org Biomol Chem
; 17(12): 3118-3128, 2019 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30730519
10.
Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.
Nat Chem Biol
; 12(12): 1023-1030, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27694802
11.
Identification and Characterization of Influenza Virus Entry Inhibitors through Dual Myxovirus High-Throughput Screening.
J Virol
; 90(16): 7368-7387, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27252534
12.
Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids.
Bioorg Med Chem Lett
; 27(4): 755-758, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28119024
13.
Evaluation of substituted ebselen derivatives as potential trypanocidal agents.
Bioorg Med Chem Lett
; 27(3): 537-541, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28043795
14.
Identification of Novel Plasmodium falciparum Hexokinase Inhibitors with Antiparasitic Activity.
Antimicrob Agents Chemother
; 60(10): 6023-33, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27458230
15.
Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State.
Antimicrob Agents Chemother
; 60(8): 4552-62, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27185801
16.
Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2.
PLoS Pathog
; 10(6): e1004213, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24967809
17.
One-pot, regiospecific assembly of (E)-benzamidines from δ- and γ-amino acids via an intramolecular aminoquinazolinone rearrangement.
Org Biomol Chem
; 14(16): 3950-5, 2016 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27050086
18.
Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.
J Biol Chem
; 288(12): 8531-8543, 2013 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382385
19.
Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold.
Bioorg Med Chem Lett
; 24(16): 3968-73, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25017033
20.
Synthesis and Evaluation of Benzylamine Inhibitors of Neuropathogenic Naegleria fowleri "Brain-Eating" Amoeba.
ACS Med Chem Lett
; 15(1): 87-92, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38229759