Detalhe da pesquisa
1.
7-(4-Alkylidenylpiperidinyl)-quinolone bacterial topoisomerase inhibitors.
Bioorg Med Chem Lett
; 24(23): 5502-6, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25455493
2.
Toll-like receptor 3 is involved in airway epithelial cell response to nontypeable Haemophilus influenzae.
Cell Immunol
; 260(2): 98-104, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-19878930
3.
In vivo activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.
Antimicrob Agents Chemother
; 53(5): 2028-33, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19273686
4.
Synthesis and antibacterial activity of 7-(1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-7-yl) quinolones.
Bioorg Med Chem Lett
; 19(17): 4933-6, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19646867
5.
Screening of large numbers of Streptococcus pneumoniae isolates for mutations associated with fluoroquinolone resistance using an oligonucleotide probe assay.
FEMS Microbiol Lett
; 217(2): 219-24, 2002 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12480107
6.
Effects of the 7-valent pneumococcal conjugate vaccine on U.S. levofloxacin-resistant Streptococcus pneumoniae.
Microb Drug Resist
; 14(3): 187-96, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18707553
7.
Sporadic occurrences of fluoroquinolone-resistant Streptococcus pneumoniae in the United States: longitudinal analysis of institutions from the New England and West South Central regions during the TRUST 4-9 (2000-2005) Surveillance Studies.
Postgrad Med
; 120(3 Suppl 1): 25-31, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18931468
8.
Decline in the prevalence of pandemic clones Spain23F-1 and Spain9V-3 among US fluoroquinolone-resistant Streptococcus pneumoniae TRUST Surveillance isolates since 2001.
Postgrad Med
; 120(3 Suppl 1): 39-45, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18931470
9.
In vitro antibacterial activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.
Antimicrob Agents Chemother
; 51(1): 361-5, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17101672
10.
Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains.
Bioorg Med Chem Lett
; 17(10): 2718-22, 2007 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17382544
11.
Infrequent occurrence of single mutations in topoisomerase IV and DNA gyrase genes among US levofloxacin-susceptible clinical isolates of Streptococcus pneumoniae from nine institutions (1999-2003).
J Antimicrob Chemother
; 57(3): 437-42, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16431861
12.
Utility of muropeptide ligase for identification of inhibitors of the cell wall biosynthesis enzyme MurF.
Antimicrob Agents Chemother
; 50(1): 230-6, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16377691
13.
Antibacterial activity of pyrrolopyridine-substituted oxazolidinones: synthesis and in vitro SAR of various C-5 acetamide replacements.
Bioorg Med Chem Lett
; 16(17): 4537-42, 2006 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16806921
14.
Novel Ser79Leu and Ser81Ile substitutions in the quinolone resistance-determining regions of ParC topoisomerase IV and GyrA DNA gyrase subunits from recent fluoroquinolone-resistant Streptococcus pneumoniae clinical isolates.
Antimicrob Agents Chemother
; 49(6): 2479-86, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15917550
15.
Identification of a dithiazoline inhibitor of Escherichia coli L,D-carboxypeptidase A.
Antimicrob Agents Chemother
; 49(11): 4500-7, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16251288
16.
Prevalence of single mutations in topoisomerase type II genes among levofloxacin-susceptible clinical strains of Streptococcus pneumoniae isolated in the United States in 1992 to 1996 and 1999 to 2000.
Antimicrob Agents Chemother
; 46(1): 119-24, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11751121
17.
Cross-resistance, relatedness and allele analysis of fluoroquinolone-resistant US clinical isolates of Streptococcus pneumoniae (1998-2000).
J Antimicrob Chemother
; 52(2): 168-75, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12837740
18.
Novel piperidinyloxy oxazolidinone antibacterial agents. Diversification of the N-Substituent.
Bioorg Med Chem
; 10(7): 2345-51, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-11983532
19.
The synthesis and antimicrobial evaluation of a new series of isoxazolinyl oxazolidinones.
Bioorg Med Chem Lett
; 14(12): 3069-72, 2004 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15149646
20.
Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones.
Bioorg Med Chem Lett
; 13(23): 4173-7, 2003 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14622996