Detalhe da pesquisa
1.
CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor α in Human Liver.
Mol Pharmacol
; 89(1): 154-64, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26467040
2.
Epigenetic modification of histone 3 lysine 27: mediator subunit MED25 is required for the dissociation of polycomb repressive complex 2 from the promoter of cytochrome P450 2C9.
J Biol Chem
; 290(4): 2264-78, 2015 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25391650
3.
Regulation of human CYP2C9 expression by electrophilic stress involves activator protein 1 activation and DNA looping.
Mol Pharmacol
; 86(2): 125-37, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24830941
4.
The influence of the CYP2C19*10 allele on clopidogrel activation and CYP2C19*2 genotyping.
Pharmacogenet Genomics
; 24(8): 381-6, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24945780
5.
RBCK1, an E3 ubiquitin ligase, interacts with and ubiquinates the human pregnane X receptor.
Drug Metab Dispos
; 41(2): 398-405, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23160820
6.
Liganded pregnane X receptor represses the human sulfotransferase SULT1E1 promoter through disrupting its chromatin structure.
Nucleic Acids Res
; 39(19): 8392-403, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21764778
7.
Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver.
Mol Pharmacol
; 82(3): 529-40, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22723340
8.
Cyclophosphamide and 4-hydroxycyclophosphamide pharmacokinetics in patients with glomerulonephritis secondary to lupus and small vessel vasculitis.
Br J Clin Pharmacol
; 74(3): 445-55, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22380717
9.
NCOA6 differentially regulates the expression of the CYP2C9 and CYP3A4 genes.
Pharmacol Res
; 63(5): 405-13, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21292004
10.
Hepatocyte nuclear factor 4{alpha} regulates rifampicin-mediated induction of CYP2C genes in primary cultures of human hepatocytes.
Drug Metab Dispos
; 38(4): 591-9, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20086032
11.
The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver.
Drug Metab Dispos
; 38(7): 1177-82, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20371638
12.
Kidney function influences warfarin responsiveness and hemorrhagic complications.
J Am Soc Nephrol
; 20(4): 912-21, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19225037
13.
Identification of human CYP2C8 as a retinoid-related orphan nuclear receptor target gene.
J Pharmacol Exp Ther
; 329(1): 192-201, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19164466
14.
CYP2C9 genotype and pharmacodynamic responses to losartan in patients with primary and secondary kidney diseases.
Eur J Clin Pharmacol
; 65(9): 947-53, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19669737
15.
Nuclear receptor coactivator 6 mediates the synergistic activation of human cytochrome P-450 2C9 by the constitutive androstane receptor and hepatic nuclear factor-4alpha.
Mol Pharmacol
; 74(3): 913-23, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18552123
16.
Midazolam metabolism in cytochrome P450 3A knockout mice can be attributed to up-regulated CYP2C enzymes.
Mol Pharmacol
; 73(3): 1029-36, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18156313
17.
Reduced methylprednisolone clearance causing prolonged pharmacodynamics in a healthy subject was not associated with CYP3A5*3 allele or a change in diet composition.
J Clin Pharmacol
; 46(5): 515-26, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16638735
18.
Functionally defective or altered CYP3A4 and CYP3A5 single nucleotide polymorphisms and their detection with genotyping tests.
Pharmacogenomics
; 6(4): 357-71, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16004554
19.
Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data.
Pharmacogenetics
; 12(3): 251-63, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11927841
20.
Analysis of the CYP2C19 polymorphism in a North-eastern Thai population.
Pharmacogenetics
; 12(3): 221-5, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11927837