Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 3 de 3
Filtrar
Mais filtros

País/Região como assunto
Tipo de documento
Intervalo de ano de publicação
1.
J Feline Med Surg ; 9(4): 309-12, 2007 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-17383920

RESUMO

Heartworm disease is caused by a mosquito-borne parasite that can affect many different mammalian species and has worldwide distribution. The agent, Dirofilaria immitis (Leidy 1856), infect mainly dogs but feline infection have been frequently reported in the last decade. Feline heartworm infection is difficult to detect, therefore, low reported prevalence could reflect true low prevalence or poor diagnostic efficiency. As mosquitoes are known to be attracted differently by different mammalian species, mosquitoes were collected from both a cattery and a contiguous home located in a canine heartworm enzootic area in Niterói, state of Rio de Janeiro, Brazil. For 14 months, mosquitoes were collected weekly for genus identification, speciation when possible, and for individual blood meal identification. Culex species mosquitoes were the most captured and those most frequently found with feline blood meal, followed by Aedes species that, although captured in lower numbers, also fed on feline blood. While Culex species mosquitoes have been reported as potential secondary heartworm vectors for dogs and primary vectors for cats, the present results suggest that Aedes species mosquitoes may also be involved in feline heartworm transmission in a larger proportion than previously thought.


Assuntos
Doenças do Gato/epidemiologia , Doenças do Gato/transmissão , Culicidae/fisiologia , Dirofilariose/epidemiologia , Dirofilariose/transmissão , Comportamento Alimentar , Insetos Vetores , Animais , Brasil/epidemiologia , Doenças do Gato/etiologia , Gatos , Culicidae/classificação , Culicidae/parasitologia , Dirofilaria immitis/isolamento & purificação , Dirofilariose/etiologia , Doenças Endêmicas , Feminino , Masculino
2.
Biomed Res Int ; 2014: 694934, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-25045693

RESUMO

Promastigote forms of Leishmania amazonensis were treated with different concentrations of two fractions of Curcuma longa cortex rich in turmerones and their respective liposomal formulations in order to evaluate growth inhibition and the minimal inhibitory concentration (MIC). In addition, cellular alterations of treated promastigotes were investigated under transmission and scanning electron microscopies. LipoRHIC and LipoRHIWC presented lower MIC, 5.5 and 12.5 µg/mL, when compared to nonencapsulated fractions (125 and 250 µg/mL), respectively, and to ar-turmerone (50 µg/mL). Parasite growth inhibition was demonstrated to be dose-dependent. Important morphological changes as rounded body and presence of several roles on plasmatic membrane could be seen on L. amazonensis promastigotes after treatment with subinhibitory concentration (2.75 µg/mL) of the most active LipoRHIC. In that sense, the hexane fraction from the turmeric cortex of Curcuma longa incorporated in liposomal formulation (LipoRHIC) could represent good strategy for the development of new antileishmanial agent.


Assuntos
Cetonas/administração & dosagem , Leishmaniose/tratamento farmacológico , Lipossomos/administração & dosagem , Extratos Vegetais/administração & dosagem , Sesquiterpenos/administração & dosagem , Química Farmacêutica , Curcuma/química , Hexanos/química , Humanos , Cetonas/química , Leishmania/efeitos dos fármacos , Leishmania mexicana/efeitos dos fármacos , Leishmania mexicana/patogenicidade , Leishmaniose/parasitologia , Lipossomos/química , Extratos Vegetais/química , Sesquiterpenos/química
3.
Mem. Inst. Oswaldo Cruz ; 96(5): 693-695, July 2001. tab
Artigo em Inglês | LILACS | ID: lil-289359

RESUMO

The identification of arthropod bloodmeals is important in many epidemiological studies, as, the understanding of the life cycle of vectors and the patogens they transmit, as well as helping to define arthropods' control strategies. The precipitin test has been used for decades, but ELISA is slowly becoming more popular. To compare the two tests for sensitivity, specificity and accuracy to detect small insect bloodmeals, Aedes aegypti or Ae. fluviatilis mosquitoes were fed either on feline, canine or human hosts. Mosquitoes were frozen at 6, 12, 24, 48 or 72 h after feeding. Precipitin test showed better specificity and accuracy and ELISA test showed higher sensitivity. Better results with both tests were achieved when mosquitoes were frozen within 48 h from feeding


Assuntos
Humanos , Animais , Feminino , Gatos , Cães , Aedes/fisiologia , Sangue , Ingestão de Alimentos , Ensaio de Imunoadsorção Enzimática/métodos , Testes de Precipitina/métodos , Criopreservação/métodos , Comportamento Alimentar , Sensibilidade e Especificidade , Fatores de Tempo
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA