Detalhe da pesquisa
1.
Identification and targeting of a unique NaV1.7 domain driving chronic pain.
Proc Natl Acad Sci U S A
; 120(32): e2217800120, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37498871
2.
A peptidomimetic modulator of the CaV2.2 N-type calcium channel for chronic pain.
Proc Natl Acad Sci U S A
; 120(47): e2305215120, 2023 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37972067
3.
Neuronal allodynic mechanisms of Slc7a5 (LAT1) in the spared nerve injury rodent model of neuropathic pain.
Pflugers Arch
; 474(4): 397-403, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35048187
4.
Cdk5-Dependent Phosphorylation of CaV3.2 T-Type Channels: Possible Role in Nerve Ligation-Induced Neuropathic Allodynia and the Compound Action Potential in Primary Afferent C Fibers.
J Neurosci
; 40(2): 283-296, 2020 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31744861
5.
Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain.
Pain
; 165(4): 866-883, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37862053
6.
Intranasal CRMP2-Ubc9 inhibitor regulates Na V 1.7 to alleviate trigeminal neuropathic pain.
Pain
; 165(3): 573-588, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751532
7.
Neuropilin-1 is a co-receptor for NGF and TrkA-evoked pain.
bioRxiv
; 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38106002
8.
Mechanism, and treatment of anti-CV2/CRMP5 autoimmune pain.
bioRxiv
; 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38766071
9.
Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain.
Neurobiol Pain
; 13: 100116, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36687466
10.
Targeting the vascular endothelial growth factor A/neuropilin 1 axis for relief of neuropathic pain.
Pain
; 164(7): 1473-1488, 2023 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36729125
11.
Intranasal CRMP2-Ubc9 Inhibitor Regulates Na V 1.7 to Alleviate Trigeminal Neuropathic Pain.
bioRxiv
; 2023 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37502910
12.
Neuropilin-1 is essential for vascular endothelial growth factor A-mediated increase of sensory neuron activity and development of pain-like behaviors.
Pain
; 164(12): 2696-2710, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37366599
13.
The natural product argentatin C attenuates postoperative pain via inhibition of voltage-gated sodium and T-type voltage-gated calcium channels.
Br J Pharmacol
; 180(9): 1267-1285, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36245395
14.
Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates.
Mol Pharmacol
; 82(4): 687-99, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22784805
15.
Plant and fungi derived analgesic natural products targeting voltage-gated sodium and calcium channels.
Channels (Austin)
; 16(1): 198-215, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36017978
16.
Cell specific regulation of NaV1.7 activity and trafficking in rat nodose ganglia neurons.
Neurobiol Pain
; 12: 100109, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36531612
17.
Conotoxin contulakin-G engages a neurotensin receptor 2/R-type calcium channel (Cav2.3) pathway to mediate spinal antinociception.
Pain
; 163(9): 1751-1762, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35050960
18.
Stereospecific Effects of Benzimidazolonepiperidine Compounds on T-Type Ca2+ Channels and Pain.
ACS Chem Neurosci
; 13(13): 2035-2047, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35671441
19.
Targeting T-type/CaV3.2 channels for chronic pain.
Transl Res
; 234: 20-30, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33422652
20.
Non-SUMOylated CRMP2 decreases NaV1.7 currents via the endocytic proteins Numb, Nedd4-2 and Eps15.
Mol Brain
; 14(1): 20, 2021 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33478555