Detalhe da pesquisa
1.
MRP.py: A Parametrizer of Post-Translationally Modified Residues.
J Chem Inf Model
; 60(10): 4424-4428, 2020 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32672967
2.
Slow-Binding Inhibition of Mycobacterium tuberculosis Shikimate Kinase by Manzamine Alkaloids.
Biochemistry
; 57(32): 4923-4933, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30063132
3.
Mutual synergy between catalase and peroxidase activities of the bifunctional enzyme KatG is facilitated by electron hole-hopping within the enzyme.
J Biol Chem
; 292(45): 18408-18421, 2017 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972181
4.
Mechanism of irreversible inhibition of Mycobacterium tuberculosis shikimate kinase by ilimaquinone.
Biochim Biophys Acta Proteins Proteom
; 1866(5-6): 731-739, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29654976
5.
A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase.
Bioorg Med Chem Lett
; 28(4): 802-808, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29366649
6.
A role for catalase-peroxidase large loop 2 revealed by deletion mutagenesis: control of active site water and ferric enzyme reactivity.
Biochemistry
; 54(8): 1648-62, 2015 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25674665
7.
Development of an ESI-LC-MS-based assay for kinetic evaluation of Mycobacterium tuberculosis shikimate kinase activity and inhibition.
Anal Chem
; 87(4): 2129-36, 2015 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25629762
8.
Inactivation of myeloperoxidase by benzoic acid hydrazide.
Arch Biochem Biophys
; 570: 14-22, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25688920
9.
Plasmodium falciparum Thioredoxin Reductase (PfTrxR) and Its Role as a Target for New Antimalarial Discovery.
Molecules
; 20(6): 11459-73, 2015 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26111176
10.
Integral role of the I'-helix in the function of the "inactive" C-terminal domain of catalase-peroxidase (KatG).
Biochim Biophys Acta
; 1834(1): 362-71, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23084782
11.
Catalase in peroxidase clothing: Interdependent cooperation of two cofactors in the catalytic versatility of KatG.
Arch Biochem Biophys
; 544: 27-39, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24280274
12.
Stimulation of KatG catalase activity by peroxidatic electron donors.
Arch Biochem Biophys
; 525(2): 215-22, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22705398
13.
Mesohaem substitution reveals how haem electronic properties can influence the kinetic and catalytic parameters of neuronal NO synthase.
Biochem J
; 433(1): 163-74, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20950274
14.
The kinetic properties producing the perfunctory pH profiles of catalase-peroxidases.
Biochim Biophys Acta
; 1784(6): 900-7, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18413236
15.
Interactions between nitric oxide and peroxynitrite during prostaglandin endoperoxide H synthase-1 catalysis: a free radical mechanism of inactivation.
Free Radic Biol Med
; 42(7): 1029-38, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17349930
16.
Selective Mycobacterium tuberculosis Shikimate Kinase Inhibitors as Potential Antibacterials.
Perspect Medicin Chem
; 7: 9-20, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25861218
17.
Enhancing the peroxidatic activity of KatG by deletion mutagenesis.
J Inorg Biochem
; 116: 106-15, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23018273
18.
Substitution of strictly conserved Y111 in catalase-peroxidases: Impact of remote interdomain contacts on active site structure and catalytic performance.
J Inorg Biochem
; 102(9): 1819-24, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18635265
19.
Catalase-peroxidase active site restructuring by a distant and "inactive" domain.
Biochemistry
; 45(23): 7113-21, 2006 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-16752901
20.
Vital roles of an interhelical insertion in catalase-peroxidase bifunctionality.
Biochem Biophys Res Commun
; 318(4): 970-6, 2004 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-15147967