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1.
J Gastrointest Surg ; 28(5): 640-650, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38704201

RESUMO

BACKGROUND: Single-anastomosis metabolic/bariatric surgery procedures may lessen the incidence of anastomotic complications. This study aimed to evaluate the feasibility and safety of performing side-to-side duodenoileal (DI) bipartition using magnetic compression anastomosis (MCA). In addition, preliminary efficacy, quality of life (QoL), and distribution of food through the DI bipartition were evaluated. METHODS: Patients with a body mass index (BMI) of ≥35.0 to 50.0 kg/m2 underwent side-to-side DI bipartition with the magnet anastomosis system (MS) with sleeve gastrectomy (SG). By endoscopic positioning, a distal magnet (250 cm proximal to the ileocecal valve) and a proximal magnet (first part of the duodenum) were aligned with laparoscopic assistance to inaugurate MCA. An isotopic study assessed transit through the bipartition. RESULTS: Between March 14, 2022 to June 1, 2022, 10 patients (BMI of 44.2 ± 1.3 kg/m2) underwent side-to-side MS DI. In 9 of 10 patients, an SG was performed concurrently. The median operative time was 161.0 minutes (IQR, 108.0-236.0), and the median hospital stay was 3 days (IQR, 2-40). Paired magnets were expelled at a median of 43 days (IQR, 21-87). There was no device-related serious advanced event within 1 year. All anastomoses were patent with satisfactory diameters after magnet expulsion and at 1 year. Respective BMI, BMI reduction, and total weight loss were 28.9 ± 1.8 kg/m2, 15.2 ± 1.8 kg/m2, and 34.2% ± 4.1%, respectively. Of note, 70.0% of patients reported that they were very satisfied. The isotopic study found a median of 19.0% of the meal transited through the ileal loop. CONCLUSION: Side-to-side MCA DI bipartition with SG in adults with class II to III obesity was feasible, safe, and efficient with good QoL at 1-year follow-up. Moreover, 19% of ingested food passed directly into the ileum.


Assuntos
Anastomose Cirúrgica , Duodeno , Estudos de Viabilidade , Gastrectomia , Imãs , Humanos , Gastrectomia/métodos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Duodeno/cirurgia , Anastomose Cirúrgica/métodos , Seguimentos , Obesidade Mórbida/cirurgia , Íleo/cirurgia , Qualidade de Vida , Laparoscopia/métodos , Índice de Massa Corporal , Duração da Cirurgia , Cirurgia Bariátrica/métodos , Resultado do Tratamento , Trânsito Gastrointestinal
2.
Diagn Microbiol Infect Dis ; 105(2): 115855, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-36462449

RESUMO

This manuscript summarizes current primary resistance of Helicobacter pylori to antibiotics in Brussels in 2021. Resistance rates were estimated at 18% for clarithromycin, 24% for levofloxacin, 52% for metronidazole, and 0% for amoxicillin and tetracycline. When compared to 2016, resistance rates remain stable, except an increase of 30% for metronidazole.


Assuntos
Infecções por Helicobacter , Helicobacter pylori , Humanos , Metronidazol/farmacologia , Infecções por Helicobacter/tratamento farmacológico , Farmacorresistência Bacteriana Múltipla , Testes de Sensibilidade Microbiana , Antibacterianos/farmacologia , Amoxicilina/farmacologia , Claritromicina/farmacologia , Levofloxacino , Farmacorresistência Bacteriana
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