Detalhe da pesquisa
1.
BCL11B and the NuRD complex cooperatively guard T-cell fate and inhibit OPA1-mediated mitochondrial fusion in T cells.
EMBO J
; 42(21): e113448, 2023 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37737560
2.
Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription.
Nucleic Acids Res
; 51(18): 10075-10093, 2023 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37650635
3.
Exonuclease editor promotes precision of gene editing in mammalian cells.
BMC Biol
; 22(1): 119, 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38769511
4.
AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns.
Nucleic Acids Res
; 50(9): 5384-5399, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35544322
5.
Generation of a genetically modified pig model with CREBRFR457Q variant.
FASEB J
; 36(11): e22611, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36250915
6.
Eliminating predictable DNA off-target effects of cytosine base editor by using dual guiders including sgRNA and TALE.
Mol Ther
; 30(7): 2443-2451, 2022 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35443934
7.
CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I.
Mol Ther
; 29(3): 1001-1015, 2021 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33221434
8.
ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems.
BMC Biol
; 18(1): 131, 2020 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967664
9.
Enhancing prime editor flexibility with coiled-coil heterodimers.
Genome Biol
; 25(1): 108, 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38671524
10.
VCFshiny: an R/Shiny application for interactively analyzing and visualizing genetic variants.
Bioinform Adv
; 3(1): vbad107, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37701675
11.
Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryos.
Mol Ther Nucleic Acids
; 34: 102035, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37808924
12.
Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation.
Genome Biol
; 24(1): 8, 2023 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36650523
13.
Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression.
Sci China Life Sci
; 65(11): 2269-2286, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35596888
14.
Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors.
Commun Biol
; 5(1): 1163, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36323848
15.
Human induced-T-to-natural killer cells have potent anti-tumour activities.
Biomark Res
; 10(1): 13, 2022 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35331335
16.
In vivo genome editing in mouse restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers.
Genome Med
; 13(1): 57, 2021 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33845891
17.
Generation of rat blood vasculature and hematopoietic cells in rat-mouse chimeras by blastocyst complementation.
J Genet Genomics
; 47(5): 249-261, 2020 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32703661
18.
Efficient base editing for multiple genes and loci in pigs using base editors.
Nat Commun
; 10(1): 2852, 2019 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31253764
19.
Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing.
Cell Discov
; 7(1): 92, 2021 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34635647
20.
Author Correction: Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing.
Cell Discov
; 7(1): 120, 2021 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34887377