Detalhe da pesquisa
1.
Discovery of potent and selective nonsteroidal indazolyl amide glucocorticoid receptor agonists.
Bioorg Med Chem Lett
; 23(19): 5442-7, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23953070
2.
Urea based CCR3 antagonists employing a tetrahydro-1,3-oxazin-2-one spacer.
Bioorg Med Chem Lett
; 19(1): 96-9, 2009 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19010676
3.
Discovery of potent and muscle selective androgen receptor modulators through scaffold modifications.
J Med Chem
; 50(13): 3015-25, 2007 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17552509
4.
Discovery and development of 5-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl-methyl]-3-thiophenecarboxylic acid (BMS-587101)--a small molecule antagonist of leukocyte function associated antigen-1.
J Med Chem
; 49(24): 6946-9, 2006 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-17125246
5.
Synthesis of novel potent dipeptidyl peptidase IV inhibitors with enhanced chemical stability: interplay between the N-terminal amino acid alkyl side chain and the cyclopropyl group of alpha-aminoacyl-l-cis-4,5-methanoprolinenitrile-based inhibitors.
J Med Chem
; 47(10): 2587-98, 2004 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15115400
6.
SAR and pH stability of cyano-substituted epothilones.
Org Lett
; 4(22): 3815-8, 2002 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-12599466
7.
Efficient asymmetric synthesis of the vasopeptidase inhibitor BMS-189921.
Org Lett
; 5(17): 3155-8, 2003 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12917005
8.
Conformational Switching and the Synthesis of Spiro[2H-indol]-3(1H)-ones by Radical Cyclization.
J Org Chem
; 64(15): 5504-5510, 1999 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-11674614
9.
Confirmation of the structure of tetra-O-(tert-butyldimethylsilyl)-D-glucono-1,4-lactone formed by silylation of D-glucono-1,5-lactone.
Carbohydr Res
; 337(6): 565-8, 2002 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11890895
10.
Cannabinoid CB(1) receptor ligand binding and function examined through mutagenesis studies of F200 and S383.
Eur J Pharmacol
; 651(1-3): 9-17, 2011 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21044623
11.
Novel synthesis of the hexahydroimidazo[1,5b]isoquinoline scaffold: application to the synthesis of glucocorticoid receptor modulators.
J Med Chem
; 53(3): 1270-80, 2010 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20047280
12.
Sulfonation with Inversion by Mitsunobu Reaction: An Improvement on the Original Conditions.
J Org Chem
; 61(22): 7955-7958, 1996 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-11667761
13.
N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation.
J Med Chem
; 52(9): 2794-8, 2009 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19351168
14.
Novel 1,4-homofragmentation via an alpha-lactone.
J Org Chem
; 71(22): 8647-50, 2006 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-17064050
15.
Determination of the absolute configuration and solution conformation of a novel disubstituted pyrrolidine acid A by vibrational circular dichroism.
Chirality
; 18(9): 746-53, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16856170
16.
A switch in enantiomer preference between mitochondrial F1F0-ATPase chemotypes.
Bioorg Med Chem Lett
; 15(11): 2749-51, 2005 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15878269
17.
One-pot synthesis and conformational features of n,n'-disubstituted ketene aminals.
J Org Chem
; 69(1): 188-91, 2004 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-14703396