Detalhe da pesquisa
1.
Preclinical Evaluation of HER2-Targeting DARPin G3: Impact of Albumin-Binding Domain (ABD) Fusion.
Int J Mol Sci
; 25(8)2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38673831
2.
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins.
Metab Eng
; 72: 171-187, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35301123
3.
Comparative Preclinical Evaluation of Peptide-Based Chelators for the Labeling of DARPin G3 with 99mTc for Radionuclide Imaging of HER2 Expression in Cancer.
Int J Mol Sci
; 23(21)2022 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36362226
4.
An engineered affibody molecule with pH-dependent binding to FcRn mediates extended circulatory half-life of a fusion protein.
Proc Natl Acad Sci U S A
; 111(48): 17110-5, 2014 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25406323
5.
Evaluation of 99mTc-Z IGF1R:4551-GGGC affibody molecule, a new probe for imaging of insulin-like growth factor type 1 receptor expression.
Amino Acids
; 47(2): 303-15, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25425114
6.
Nanoparticles targeting the intestinal Fc receptor enhance intestinal cellular trafficking of semaglutide.
J Control Release
; 366: 621-636, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38215986
7.
Half-life extension via ABD-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.
J Control Release
; 370: 468-478, 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38697314
8.
[99mTc(CO)3]+-(HE)3-ZIGF1R:4551, a new Affibody conjugate for visualization of insulin-like growth factor-1 receptor expression in malignant tumours.
Eur J Nucl Med Mol Imaging
; 40(3): 439-49, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23179942
9.
Comparison of HER2-targeted affibody conjugates loaded with auristatin- and maytansine-derived drugs.
J Control Release
; 355: 515-527, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36773960
10.
Evaluation of a HER2-targeting affibody molecule combining an N-terminal HEHEHE-tag with a GGGC chelator for 99mTc-labelling at the C terminus.
Tumour Biol
; 33(3): 641-51, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22249974
11.
Preclinical Evaluation of a New Format of 68Ga- and 111In-Labeled Affibody Molecule ZIGF-1R:4551 for the Visualization of IGF-1R Expression in Malignant Tumors Using PET and SPECT.
Pharmaceutics
; 14(7)2022 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890370
12.
Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules.
Biomedicines
; 10(6)2022 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35740315
13.
Effect of Inter-Domain Linker Composition on Biodistribution of ABD-Fused Affibody-Drug Conjugates Targeting HER2.
Pharmaceutics
; 14(3)2022 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35335898
14.
Experimental HER2-Targeted Therapy Using ADAPT6-ABD-mcDM1 in Mice Bearing SKOV3 Ovarian Cancer Xenografts: Efficacy and Selection of Companion Imaging Counterpart.
Pharmaceutics
; 14(8)2022 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36015242
15.
Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis.
Sci Adv
; 8(17): eabn1823, 2022 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35476434
16.
Affibody-Derived Drug Conjugates Targeting HER2: Effect of Drug Load on Cytotoxicity and Biodistribution.
Pharmaceutics
; 13(3)2021 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33806887
17.
Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein.
Pharmaceutics
; 13(11)2021 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34834262
18.
Influence of the Position and Composition of Radiometals and Radioiodine Labels on Imaging of Epcam Expression in Prostate Cancer Model Using the DARPin Ec1.
Cancers (Basel)
; 13(14)2021 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34298801
19.
The Influence of Domain Permutations of an Albumin-Binding Domain-Fused HER2-Targeting Affibody-Based Drug Conjugate on Tumor Cell Proliferation and Therapy Efficacy.
Pharmaceutics
; 13(11)2021 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34834389
20.
Imaging-Guided Therapy Simultaneously Targeting HER2 and EpCAM with Trastuzumab and EpCAM-Directed Toxin Provides Additive Effect in Ovarian Cancer Model.
Cancers (Basel)
; 13(16)2021 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34439094