Detalhe da pesquisa
1.
Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer.
Cell
; 175(5): 1244-1258.e26, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30454645
2.
Invadopodia-mediated ECM degradation is enhanced in the G1 phase of the cell cycle.
J Cell Sci
; 132(20)2019 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31533971
3.
CTIP2 is a negative regulator of P-TEFb.
Proc Natl Acad Sci U S A
; 110(31): 12655-60, 2013 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23852730
4.
Derivation of human primary prostate epithelial cell lines by differentially targeting the CDKN2A locus along with expression of hTERT.
Res Sq
; 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38766032
5.
Autophagy Contributes to Homeostasis in Esophageal Epithelium Where High Autophagic Vesicle Level Marks Basal Cells With Limited Proliferation and Enhanced Self-Renewal Potential.
Cell Mol Gastroenterol Hepatol
; 18(1): 15-40, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38452871
6.
Protocol to assess substrate dephosphorylation by serine/threonine phosphoprotein phosphatases in vitro.
STAR Protoc
; 4(2): 102148, 2023 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37074907
7.
FAM122A ensures cell cycle interphase progression and checkpoint control as a SLiM-dependent substrate-competitive inhibitor to the B55âº/PP2A phosphatase.
bioRxiv
; 2023 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945596
8.
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.
Mol Cancer Ther
; 2023 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38064712
9.
Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.
Cancer Res Commun
; 2(11): 1355-1371, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36643868
10.
B55alpha PP2A holoenzymes modulate the phosphorylation status of the retinoblastoma-related protein p107 and its activation.
J Biol Chem
; 285(39): 29863-73, 2010 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20663872
11.
Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells.
Gastroenterology
; 138(5): 1920-30, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20100483
12.
Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase.
Prostate Cancer Prostatic Dis
; 24(1): 233-243, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32873916
13.
PP2A/B55α substrate recruitment as defined by the retinoblastoma-related protein p107.
Elife
; 102021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34661528
14.
Selective control of gene expression by CDK9 in human cells.
J Cell Physiol
; 222(1): 200-8, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19780058
15.
p21 loss cooperates with INK4 inactivation facilitating immortalization and Bcl-2-mediated anchorage-independent growth of oncogene-transduced primary mouse fibroblasts.
Cancer Res
; 67(9): 4130-7, 2007 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17483323
16.
PP2A holoenzymes, substrate specificity driving cellular functions and deregulation in cancer.
Adv Cancer Res
; 144: 55-93, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31349904
17.
PPP2R2A prostate cancer haploinsufficiency is associated with worse prognosis and a high vulnerability to B55α/PP2A reconstitution that triggers centrosome destabilization.
Oncogenesis
; 8(12): 72, 2019 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31822657
18.
Direct inhibition of CDK9 blocks HIV-1 replication without preventing T-cell activation in primary human peripheral blood lymphocytes.
Gene
; 405(1-2): 65-78, 2007 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17949927
19.
CDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2.
Mol Cell Biol
; 23(15): 5165-73, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12861003
20.
Cyclin-dependent kinase 4 expression is essential for neu-induced breast tumorigenesis.
Cancer Res
; 65(22): 10174-8, 2005 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16288002