Antibiotic treatment for appendicitis in Norway and Sweden: a nationwide survey on treatment practices.

BACKGROUND: Appendicitis is one of the most common causes of acute abdomen. Uncomplicated appendicitis is as an inflamed appendix without perforation, gangrene or abscess formation. Recent trials show that one can safely treat uncomplicated appendicitis with antibiotics, given patient approval and appropriate follow-up. A recent study has also indicated no difference between antibiotic treatment and placebo. Our aim was to investigate if Norwegian and Swedish surgical departments treat uncomplicated appendicitis with antibiotics and to explore their opinions on this treatment practice. METHODS: A questionnaire was distributed to all heads of department in hospitals that treat appendicitis in Norway and Sweden. Answers were collected using a REDCap survey. Answers were compared between centers and nations and the results were presented anonymously. RESULTS: We sent the questionnaire to 94 eligible recipients and received 61 (65%) answers. In total, 8/61 (13%) departments stated that they have established antibiotic treatment as sole treatment for uncomplicated appendicitis. Almost half of the responders stated that they have used antibiotics sporadically to treat uncomplicated appendicitis. Lack of evidence and guidelines were noted as reasons why antibiotic treatment has not been implemented as sole treatment. CONCLUSIONS: Most Norwegian and Swedish departments have not implemented antibiotic treatment as the sole treatment for uncomplicated appendicitis. Despite several recent large trials on this subject, lack of evidence and guidelines was the most frequently reported reason in our survey.

The impact of postpartum post-traumatic stress disorder symptoms on child development: a population-based, 2-year follow-up study.

BACKGROUND: Against the background of very limited evidence, the present study aimed to prospectively examine the impact of maternal postpartum post-traumatic stress disorder (PTSD) symptoms on four important areas of child development, i.e. gross motor, fine motor, communication and social-emotional development. METHOD: This study is part of the large, population-based Akershus Birth Cohort. Data from the hospital's birth record as well as questionnaire data from 8 weeks and 2 years postpartum were used (n = 1472). The domains of child development that were significantly correlated with PTSD symptoms were entered into regression analyses. Interaction analyses were run to test whether the influence of postpartum PTSD symptoms on child development was moderated by child sex or infant temperament. RESULTS: Postpartum PTSD symptoms had a prospective relationship with poor child social-emotional development 2 years later. This relationship remained significant even when adjusting for confounders such as maternal depression and anxiety or infant temperament. Both child sex and infant temperament moderated the association between maternal PTSD symptoms and child social-emotional development, i.e. with increasing maternal PTSD symptom load, boys and children with a difficult temperament were shown to have comparatively higher levels of social-emotional problems. CONCLUSIONS: Examining four different domains of child development, we found a prospective impact of postpartum PTSD symptoms on children's social-emotional development at 2 years of age. Our findings suggest that both boys and children with an early difficult temperament may be particularly susceptible to the adverse impact of postpartum PTSD symptoms. Additional studies are needed to further investigate the mechanisms at work.

Breastfeeding and pelvic girdle pain: a follow-up study of 10,603 women 18 months after delivery.

OBJECTIVE: To study the associations of patterns and duration of breastfeeding with the persistence of pelvic girdle pain 18 months after delivery. DESIGN: Longitudinal population study. SETTING: Norway, for the period 1999-2011. POPULATION: A follow-up of 10 603 women with singleton deliveries in the Norwegian Mother and Child Cohort Study who reported pelvic girdle pain at 0-3 months postpartum. METHODS: Data were obtained by four self-administered questionnaires and linked to the Medical Birth Registry of Norway. MAIN OUTCOME MEASURE: Pelvic girdle pain, defined as combined anterior and bilateral posterior pelvic pain, 18 months after delivery. RESULTS: Eighteen months after delivery, 7.8% of respondents (829/10,603) reported pelvic girdle pain. Breastfeeding patterns at 5 months after delivery were not associated with persistence of pelvic girdle pain. The proportion of women with pelvic girdle pain 18 months after delivery increased as the duration of breastfeeding decreased (test for trend, P < 0.001). The estimated associations attenuated after adjustment for educational level, smoking status, and body mass index, but remained statistically significant for the association between 0 and 2 months of breastfeeding and persistent pelvic girdle pain (adjusted odds ratio 1.34; 95% confidence interval 1.03-1.75). The association of short breastfeeding duration with persistent pelvic girdle pain was only present in women with body mass index ≥25 kg/m(2) . CONCLUSIONS: Breastfeeding was associated with a small beneficial effect on the recovery process of pelvic girdle pain in women with a body mass index ≥25 kg/m(2) . Among women with pelvic girdle pain, breastfeeding should be encouraged in accordance with the existing child-feeding recommendations.

Hormonal contraception and pelvic girdle pain during pregnancy: a population study of 91,721 pregnancies in the Norwegian Mother and Child Cohort.

STUDY QUESTION: Is pre-pregnancy hormonal contraception use associated with the development of pelvic girdle pain during pregnancy? SUMMARY ANSWER: In contrast to combined oral contraceptive pills, long lifetime exposure to progestin-only contraceptive pills or the use of a progestin intrauterine device during the final year before pregnancy were associated with pelvic girdle pain. WHAT IS ALREADY KNOWN: Pelvic girdle pain severely affects many women during pregnancy. Smaller studies have suggested that hormonal contraceptive use is involved in the underlying mechanisms, but evidence is inconclusive. STUDY DESIGN, SIZE, DURATION: A population study during the years 1999-2008. PARTICIPANTS/MATERIALS, SETTING, METHODS: A total of 91,721 pregnancies included in the Norwegian Mother and Child Cohort Study. Data were obtained by two self-administered questionnaires during pregnancy weeks 17 and 30. MAIN RESULTS AND THE ROLE OF CHANCE: Pelvic girdle pain was present in 12.9% of women who had used combined oral contraceptive pills during the last pre-pregnancy year, 16.4% of women who had used progestin-only contraceptive pills, 16.7% of women who had progestin injections and 20.7% of women who had used progestin intrauterine devices, compared with 15.3% of women who did not report use of hormonal contraceptives. After adjustment for other study factors, the use of a progestin intrauterine device was the only factor based on the preceding year associated with pelvic girdle pain [adjusted odds ratios (OR) 1.20; 95% confidence interval (CI): 1.11-1.31]. Long lifetime exposure to progestin-only contraceptive pills was also associated with pelvic girdle pain (adjusted OR 1.49; 95% CI: 1.01-2.20). LIMITATIONS, REASONS FOR CAUTION: The participation rate was 38.5%. However, a recent study on the potential biases of skewed selection in the Norwegian Mother and Child Cohort Study found the prevalence estimates but not the exposure-outcome associations to be influenced by the selection. WIDER IMPLICATIONS OF THE FINDINGS: The results suggest that combined oral contraceptives can be used without fear of developing pelvic girdle pain during pregnancy. However, the influence of progestin intrauterine devices and long-term exposure to progestin-only contraceptive pills requires further study. STUDY FUNDING/COMPETING INTEREST(S): The present study was supported by the Norwegian Research Council. None of the authors has a conflict of interest.

Sick leave during pregnancy: a longitudinal study of rates and risk factors in a Norwegian population.

OBJECTIVE: To describe the prevalence of, reasons given for, and factors associated with sick leave during pregnancy. DESIGN: Longitudinal, population-based descriptive study. SETTING: Akershus University Hospital, Norway. POPULATION: All women scheduled to give birth at the hospital (November 2008 to April 2010). METHODS: Consenting women were handed a questionnaire at the routine ultrasound check at 17 weeks of gestation. Women returning this questionnaire received a second questionnaire at 32 weeks of gestation. Multiple logistic regression analyses were performed to examine associations with somatic, psychiatric and social factors. MAIN OUTCOME MEASURES: Rates and duration of sick leave. RESULTS: By 32 weeks of gestation, 63.2% of the 2918 women included were on sick leave, and 75.3% had been on sick leave at some point during their pregnancy. Pelvic girdle pain and fatigue/sleep problems were the main reasons given for sick leave. Being on sick leave in all trimesters was strongly associated with hyperemesis, exercising less than weekly, chronic pain before or during pregnancy, infertility treatment (all P < 0.001); younger maternal age, conflicts in the workplace (both P < 0.01); multiparity, previous depression, insomnia and lower education (all P < 0.05). Sick leave was associated with elective caesarean section and higher infant birthweight (P < 0.01). Adjustment of the work situation was associated with 1 week shorter duration of sick leave. CONCLUSIONS: Most women receive sick leave during pregnancy, but sick leave might not be caused by pregnancy alone. Previous medical and psychiatric history, work conditions and socio-economic factors need to be addressed to understand sick leave during pregnancy.

The effect of emotional distress on persistent pelvic girdle pain after delivery: a longitudinal population study.

OBJECTIVE: To study the prognosis for pelvic girdle pain, and to explore the association between presence of emotional distress during pregnancy and pelvic girdle syndrome 6 months after delivery. DESIGN: Longitudinal population study. SETTING: Norway, for the period 1999-2008. POPULATION: A follow-up of 41 421 women in the Norwegian Mother and Child Cohort who reported pelvic girdle pain at 30 weeks of gestation. METHODS: Data were obtained by self-administered questionnaires in weeks 17 and 30 of gestation, and 6 months after delivery. MAIN OUTCOME MEASURE: Pelvic girdle syndrome 6 months after delivery, defined as pain in the anterior pelvis and on both sides in the posterior pelvis. RESULTS: Six months after delivery, 78.0% of the women had recovered, 18.5% reported persistent pain in one or two pelvic locations, 3.0% reported pelvic girdle syndrome and 0.5% reported severe pelvic girdle syndrome. The recovery rates decreased with increasing levels of pain severity in pregnancy. Being emotionally distressed at two time points during pregnancy was associated with the presence of pelvic girdle syndrome (adjusted OR 1.5, 95% CI 1.2-1.9) and severe pelvic girdle syndrome (adjusted OR 1.9, 95% CI 1.1-3.1), after adjustment for pain severity in pregnancy, other medical conditions, body mass index, age at menarche, previous low back pain, and smoking during pregnancy. CONCLUSIONS: In this follow-up of women with pelvic girdle pain in pregnancy, the recovery rates after delivery were high. Our findings suggest that the presence of emotional distress during pregnancy is independently associated with the persistence of pelvic girdle pain after delivery.

Fear of childbirth and duration of labour: a study of 2206 women with intended vaginal delivery.

OBJECTIVE: To assess the association between fear of childbirth and duration of labour. DESIGN: A prospective study of women from 32 weeks of gestation through to delivery. SETTING: Akershus University Hospital, Norway. POPULATION: A total of 2206 pregnant women with a singleton pregnancy and intended vaginal delivery during the period 2008-10. METHODS: Fear of childbirth was assessed by the Wijma Delivery Expectancy Questionnaire (W-DEQ) version A at 32 weeks of gestation, and defined as a W-DEQ sum score ≥ 85. Information on labour duration, use of epidural analgesia and mode of delivery was obtained from the maternal ward electronic birth records. MAIN OUTCOME MEASURES: Labour duration in hours: from 3-4 cm cervical dilatation and three uterine contractions per 10 minutes lasting ≥ 1 minute, until delivery of the child. RESULTS: Fear of childbirth (W-DEQ sum score ≥ 85) was present in 7.5% (165) of women. Labour duration was significantly longer in women with fear of childbirth compared with women with no such fear using a linear regression model (crude unstandardized coefficient 1.54; 95% confidence interval 0.87-2.22, corresponding to a difference of 1 hour and 32 minutes). After adjustment for parity, counselling for pregnancy concern, epidural analgesia, labour induction, labour augmentation, emergency caesarean delivery, instrumental vaginal delivery, offspring birthweight and maternal age, the difference attenuated, but remained statistically significant (adjusted unstandardized coefficient 0.78; 95% confidence interval 0.20-1.35, corresponding to a 47-minute difference). CONCLUSION: Duration of labour was longer in women with fear of childbirth than in women without fear of childbirth.

Mode of delivery and postpartum emotional distress: a cohort study of 55,814 women.

OBJECTIVE: To assess the association between mode of delivery and maternal postpartum emotional distress. DESIGN: A prospective study of women from 30 weeks of gestation to 6 months postpartum. SETTING: Pregnant women in Norway during the period 1998-2008. POPULATION: A total of 55,814 women from the Norwegian Mother and Child Cohort Study. METHODS: Emotional distress was reported in a short form of the Hopkins Symptom Checklist-25 (SCL-8) at 30 weeks of gestation and at 6 months postpartum. Information on mode of delivery was obtained from the Medical Birth Registry of Norway. MAIN OUTCOME MEASURES: Changes in SCL-8 score from 30 weeks of gestation to 6 months postpartum and presence of emotional distress at 6 months postpartum. RESULTS: Women with instrumental vaginal, emergency caesarean or elective caesarean deliveries had similar changes in SCL-8 score between 30 weeks of gestation and 6 months postpartum, as compared with women with unassisted vaginal delivery (adjusted regression coefficient, 0.00, 95% CI -0.01 to 0.01; 0.01, 95% CI 0.00-0.02; and -0.01, 95% CI -0.02 to 0.00, respectively). The corresponding odds ratios (ORs) associated with the presence of emotional distress at 6 months postpartum (SCL-8 ≥ 2.0) were: OR 1.01, 95% CI 0.86-1.18; OR 1.13, 95% CI 0.97-1.32; and OR 0.96, 95% CI 0.79-1.16, respectively. These estimates were adjusted for emotional distress during pregnancy and other potential confounding factors. Emotional distress during pregnancy showed the strongest association with the presence of emotional distress at 6 months postpartum (adjusted OR 14.09, 95% CI 12.77-15.55). CONCLUSIONS: Mode of delivery was not associated with a change in SCL-8 score from 30 weeks of gestation to 6 months postpartum or with the presence of emotional distress postpartum.

Age at menarche and pelvic girdle syndrome in pregnancy: a population study of 74 973 women.

OBJECTIVE: To study the association of age at menarche with presence of pelvic girdle syndrome in pregnancy. DESIGN: Population study. SETTING: Norway 1999-2007. POPULATION: A total of 74 973 pregnant women in the Norwegian Mother and Child Cohort Study. METHODS: Data were obtained by self-administered questionnaires in weeks 17 and 30 of gestation. MAIN OUTCOME MEASURE: Pelvic girdle syndrome in pregnancy at 30 weeks of gestation, defined as pain in the pubic symphysis in the anterior pelvis and in both sacroiliac joints in the posterior pelvis. RESULTS: The prevalence of pelvic girdle syndrome was 20.6% (328/1593) in women with menarche before the age of 11, it was 16.3% (3200/22 044) in women with menarche at the age of 12 and 12.7% (1252/9859) in women with menarche after the age of 14 (chi-square test for trend, P < 0.001). The inverse association of age at menarche with pelvic girdle syndrome remained after adjustment for body mass index, maternal age, parity, educational level, previous low back pain, emotional distress and physically demanding work. Women with early menarche and high body mass index had the highest prevalence of pelvic girdle syndrome, but the association of early menarche with pelvic girdle syndrome was similar in women with and without high body mass index. CONCLUSIONS: Early menarche was associated with increased prevalence of pelvic girdle syndrome in pregnancy. Factors associated with early menarche may play a role in the development of pelvic girdle pain.

Subjective and objective sleep among depressed and non-depressed postnatal women.

OBJECTIVE: Women sleep less in the postnatal period and it has been suggested that mothers diagnosed with depression alternatively could be suffering from the effects of chronic sleep deprivation. METHOD: From a population-based study, we recruited 42 women, of whom 21 scored >or=10 on the Edinburgh Postnatal Depression Scale. Sleep was registered by the Pittsburgh Sleep Quality Index (PSQI), sleep diaries and actigraphy 2 months after delivery. RESULTS: There were significant differences in subjective sleep measured retrospectively by the PSQI between depressed and non-depressed women. In contrast, there were no significant differences in sleep measured prospectively by sleep diaries and actigraphy. Both depressed and non-depressed women had impaired sleep efficiency (82%) and were awake for about 1.5 h during the night. Primipara had worse sleep, measured by actigraphy, compared with multipara. CONCLUSION: Measured objectively and prospectively, women with depression did not have worse sleep than non-depressed women.

[Eating habits in children under 2 years old according to ethnic origin in a Barcelona urban area]. / Hábitos alimentarios de niños menores de 2 años según el origen étnico de los progenitores en un área urbana de Barcelona.

INTRODUCTION: The importance of the influence of diet in the first few years of life on child growth and development and its relationship with the prevention of chronic diseases in childhood and adulthood has recently been stressed. The aim of the present study was to determine the presence or absence of inappropriate feeding practices, defined as non-compliance with dietary recommendations, in children aged less than 2 years old through a survey. SUBJECTS AND METHODS: The parents of 462 children were administered a 14-item questionnaire on compliance with dietary recommendations to define nutritional risk. Depending on the parents' country of birth, children were classified as autochthonous, gypsy, or non-autochthonous. RESULTS: In absolute results, high percentages of non-compliance with a substantial number of recommendations were found in all children and in each of the three groups, with the consequent danger of nutritional risk. CONCLUSIONS: In children in our environment, there are numerous inadequate feeding practices that constitute nutritional risk factors and require preventive and educational interventions to improve the future health of these children when they reach adulthood. In children from ethnic groups, no particularly severe inadequate feeding practices related to origin were found. The gypsy ethnic group requires additional nutritional health education interventions. Health workers should improve the information provided on nutritional recommendations and feeding practices to avoid misunderstanding, as in the case of gluten.

Depression during pregnancy and after delivery: a repeated measurement study.

The aim of this study was to examine the risk of depression in the postpartum period (first four months after delivery) as compared to the remaining postnatal year and the pregnancy period. All postpartum women from two municipalities in Norway were included in a questionnaire study of mental health (n = 416). Over 50% of the women (n = 259) answered an identical questionnaire at an additional time either before or after the postpartum period. The level of depression was measured by the Edinburgh Postnatal Depression Scale (EPDS) and the Hopkins Symptom Check List-25 items (SCL-25). The point prevalence of depression (EPDS> or =10) in the first four months postpartum did not differ significantly as compared to other time periods during pregnancy and the postnatal year. This finding remained also after controlling for other risk factors of depression; high score on the life event scale, prior depression and poor partner relationship. There was a non-significant trend of lower prevalence of depression during early pregnancy and after the first eight postnatal months. In conclusion, our findings suggest that the first four months postpartum were not distinguished by higher depression prevalence as compared to other time periods during pregnancy and the first postnatal year.

A short matrix-version of the Edinburgh Depression Scale.

OBJECTIVE: Given the importance of depression as a world health problem, depression assessment should be standard practice in large-scale health surveys. The aim of the study was to construct a short matrix-version of the Edinburgh Depression Scale (EDS) that can be used in questionnaire studies. METHOD: On the basis of the complete EDS scale of ten items, answered by 2730 women, stepwise multiple regression analysis was used to find the combination of items that explains the maximum proportion of the variance of the full scale sum score. The selected EDS items were thereafter correlated with the Hopkins Symptom Check List (SCL-25) for external validation. RESULTS: The sum of five selected items from the EDS correlated at r = 0.96 with the full version. The EDS-5 scores correlated strongly with the SCL-25 (r = 0.75). CONCLUSION: The EDS-5 version shows good psychometric properties and may, for some scientific purposes, substitute the full EDS scale.

[The importance of cooperation in primary health care. Utilization of physicians' services and home nursing services during different degrees of cooperation]. / Betydning av samarbeid i helsetjenesten. Forbruk av legetjenester og hjemmesykepleie ved ulike grader av samarbeid om felles pasienter.

A study carried out in the county of Vestfold in the spring of 1989 clearly showed how cooperation between doctor and nurse influenced the level and quality of care provided by doctors to patients nursed at home. Good cooperation coincided with high quality health services, and ensured rational use of resources in relation to the patients' needs. The study showed that the quality and frequency of cooperation between doctor and nurse are of utmost importance for the service given to the patients.

[The accessibility of patients' personal physicians and quality of care of patients under home nursing care]. / Tilgjengeligheten og servicenivået til den faste legen for pasienter i hjemmesykepleien.

A study was carried out in the county of Vestfold in the spring of 1989 to establish the quality and quantity of the medical services for patients nursed at home. The study showed that doctors in rural districts provide better service than doctors in the towns. This difference is particularly noticeable in the case of patients who are acutely ill. The study also showed that patient-doctor contacts are seldom for patients nursed at home, with an average frequency of one every eight weeks for consulting-room consultations and one every 15 weeks for visits to the home.

[Postnatal care--sleep, rest and satisfaction]. / Barselomsorg--søvn, hvile og tilfredshet.

BACKGROUND: During the last decade most hospitals in Norway have introduced breastfeeding according to the baby's needs during night-time as well. The aim of this study was to examine whether women had sufficient sleep and rest in the maternity unit, and the factors influencing insufficient sleep and rest. The degree of satisfaction with the stay in the maternity unit and factors associated with satisfaction were also studied. MATERIAL AND METHODS: From April to November 1998, 160 postnatal women in two Norwegian communities were included in a questionnaire-based study, representing 89% of all women eligible for the study. RESULTS: 47% (75/160) of the women reported lack of sleep and rest in the maternity unit. The factor most strongly associated with lack of sleep and rest was not having a single room (adjusted odds ratio 11.0; 95% confidence interval: 1.7-69.1). 56% (88/158) of the women reported to be very satisfied, 39% (68/158) were moderately satisfied, and 5% (8/158) dissatisfied with the stay at the maternity unit. Not being very satisfied was associated with the hospital of delivery (adjusted OR 18.0; 95% CI: 2.2-149.1), and with insufficient sleep and rest (OR 3.3: 1.3-8.1). INTERPRETATION: Our results suggest that women do not get sufficient sleep and rest under existing circumstances in maternity units.

Depression in postpartum and non-postpartum women: prevalence and risk factors.

OBJECTIVE: The aim of the study was to assess the prevalence of depression in postpartum women as compared with non-postpartum women, and to identify risk factors of depression in both groups. METHOD: A population based questionnaire study was performed among women 18-40 years in two municipalities in Norway in 1998-1999. A total of 2,730 women were included, of whom 416 were in the postpartum period. RESULTS: The prevalence of depression was higher in non-postpartum as compared with postpartum women. High scores on the life event scale, a history of depression and a poor relationship to the partner were associated with depression in both postpartum and non-postpartum women. When controlling for the identified risk factors of depression the odds-ratio for depression in the postpartum period was 1.6 (95% CI: 1.0-2.6). CONCLUSION: The risk for depression was increased in the postpartum period, when controlling for the uneven distribution of risk factors.

The Edinburgh Postnatal Depression Scale: validation in a Norwegian community sample.

This study was undertaken to validate a Norwegian translation of the Edinburgh Postnatal Depression Scale (EPDS). The EPDS was validated against the DSM-IV criteria for major depression, derived from the PRIME-MD, in an interview study of 56 women selected from a community-based questionnaire study of 310 women 6 weeks postpartum. A score of > or =10 on the EPDS scale identified all women with major depression, giving a sensitivity of 100% (95% confidence interval; 72%-100%) and a specificity of 87% (95% confidence interval; 77%-95%). The EPDS scores were strongly correlated with the Montgomery-Asberg Depression Rating Scale in the subsample of women interviewed (n=56) and with the Hopkins Symptom Check List (SCL-25) scores in the questionnaire study (n=310). Our results with regard to the sensitivity and specificity estimates are comparable with prior validation studies; however, the confidence intervals around the estimates are wide. Nevertheless, this study confirms that the EPDS is a valid clinical screening instrument for detecting postpartum depression.

Review of validation studies of the Edinburgh Postnatal Depression Scale.

OBJECTIVE: To review validation studies of the Edinburgh Postnatal Depression Scale (EPDS). METHOD: A systematic search was performed in Medline and the Science Citation Index Expanded (ISI) from the period 1987-2000. For sensitivity and specificity of the EPDS presented in each study, 95% confidence intervals were estimated. Positive and negative predictive values were estimated assuming prevalences of postpartum depression ranging from 5% to 20%. RESULTS: Eighteen validation studies were identified. The study design varied between studies. The sensitivity and specificity estimates also varied: 65-100% and 49-100%, respectively. The confidence intervals were estimated to be wide. Our estimates suggest a lower positive predictive value in a normal population than in the validation study samples. CONCLUSION: Most studies show a high sensitivity of the EPDS. Because of the differences in study design and large confidence intervals, uncertainty remains regarding the comparability between the sensitivity and specificity estimates of the different EPDS versions.