Detalhe da pesquisa
1.
Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments.
Mol Cell
; 72(1): 19-36.e8, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30244836
2.
Dynamic activation and regulation of the mitogen-activated protein kinase p38.
Proc Natl Acad Sci U S A
; 115(18): 4655-4660, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29666261
3.
Evolutionarily Conserved Interactions within the Pore Domain of Acid-Sensing Ion Channels.
Biophys J
; 118(4): 861-872, 2020 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31630811
4.
Analysis of the Destabilization of Bacterial Membranes by Quaternary Ammonium Compounds: A Combined Experimental and Computational Study.
Chembiochem
; 21(10): 1510-1516, 2020 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31859426
5.
Patterns of coevolving amino acids unveil structural and dynamical domains.
Proc Natl Acad Sci U S A
; 114(50): E10612-E10621, 2017 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29183970
6.
Cross-kingdom auxiliary subunit modulation of a voltage-gated sodium channel.
J Biol Chem
; 293(14): 4981-4992, 2018 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29371400
7.
Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac.
Proc Natl Acad Sci U S A
; 113(48): 13762-13767, 2016 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27856739
8.
Mining Protein Evolution for Insights into Mechanisms of Voltage-Dependent Sodium Channel Auxiliary Subunits.
Handb Exp Pharmacol
; 246: 33-49, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29464397
9.
Characterization of the free-energy landscapes of proteins by NMR-guided metadynamics.
Proc Natl Acad Sci U S A
; 110(17): 6817-22, 2013 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23572592
10.
Native fold and docking pose discrimination by the same residue-based scoring function.
Proteins
; 83(4): 621-30, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25619680
11.
Identification and engineering of potent cyclic peptides with selective or promiscuous binding through biochemical profiling and bioinformatic data analysis.
RSC Chem Biol
; 5(1): 12-18, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38179194
12.
Conserved conformational dynamics determine enzyme activity.
Sci Adv
; 8(31): eabo5546, 2022 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921420
13.
Sequence and structural conservation reveal fingerprint residues in TRP channels.
Elife
; 112022 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35686986
14.
An integrated platform approach enables discovery of potent, selective and ligand-competitive cyclic peptides targeting the GIP receptor.
Chem Sci
; 13(11): 3256-3262, 2022 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35414877
15.
Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli.
Commun Biol
; 4(1): 980, 2021 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34408246
16.
Polyamine blockade and binding energetics in the MthK potassium channel.
J Gen Physiol
; 152(7)2020 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32342093
17.
Propofol inhibits prokaryotic voltage-gated Na+ channels by promoting activation-coupled inactivation.
J Gen Physiol
; 150(9): 1299-1316, 2018 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30018038
18.
A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine.
J Gen Physiol
; 150(11): 1554-1566, 2018 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333107
19.
Ion Channel Sensing: Are Fluctuations the Crux of the Matter?
J Phys Chem Lett
; 9(6): 1260-1264, 2018 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29439562
20.
Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites.
J Gen Physiol
; 150(9): 1317-1331, 2018 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30018039