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1.
Opt Lett ; 40(12): 2688-91, 2015 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-26076237

RESUMO

The effect of a tunable, externally coupled Fabry-Perot cavity to resonantly enhance the optical Hall effect signatures at terahertz frequencies produced by a traditional Drude-like two-dimensional electron gas is shown and discussed in this Letter. As a result, the detection of optical Hall effect signatures at conveniently obtainable magnetic fields, for example, by neodymium permanent magnets, is demonstrated. An AlInN/GaN-based high-electron mobility transistor structure grown on a sapphire substrate is used for the experiment. The optical Hall effect signatures and their dispersions, which are governed by the frequency and the reflectance minima and maxima of the externally coupled Fabry-Perot cavity, are presented and discussed. Tuning the externally coupled Fabry-Perot cavity strongly modifies the optical Hall effect signatures, which provides a new degree of freedom for optical Hall effect experiments in addition to frequency, angle of incidence, and magnetic field direction and strength.

2.
Rev Med Suisse ; 10(431): 1136-40, 2014 May 21.
Artigo em Francês | MEDLINE | ID: mdl-24941687

RESUMO

A better understanding of the molecular deregulation leading to carcinogenesis allows the development of numerous novel targeted therapeutic candidates. Clinical research in oncology is a critical step to evaluate in a thorough manner the safety and efficacy of these innovative compounds. During the last four years the fruitful partnership between the Geneva University Hospitals and the Dr. Henri Dubois-Ferriere Dinu Lipatti Foundation lead to a dedicated clinical research unit for cancer patients with a staff of ten people. Since 2010, more than 300 patients were enrolled in more than 70 distinct clinical trials evaluating novel therapies for both solid tumors and hematologic malignancies. Interestingly, classical cytostatic drugs now represent only a small fraction of the new anti-cancer therapies in the pipeline.


Assuntos
Pesquisa Biomédica/organização & administração , Hematologia/organização & administração , Hospitais Universitários/organização & administração , Oncologia/organização & administração , Unidades Hospitalares/organização & administração , Humanos , Parcerias Público-Privadas , Suíça
3.
Ultramicroscopy ; 264: 114006, 2024 Jun 09.
Artigo em Inglês | MEDLINE | ID: mdl-38878506

RESUMO

The electron optical phase contrast probed by electron holography at n-n+ GaN doping steps is found to exhibit a giant enhancement, in sharp contrast to the always smaller than expected phase contrast reported for p-n junctions. We unravel the physical origin of the giant enhancement by combining off-axis electron holography data with self-consistent electrostatic potential calculations. The predominant contribution to the phase contrast is shown to arise from the doping dependent screening length of the surface Fermi-level pinning, which is induced by FIB-implanted carbon point defects below the outer amorphous shell. The contribution of the built-in potential is negligible for modulation doping and only relevant for large built-in potentials at e.g. p-n junctions. This work provides a quantitative approach to so-called dead layers at TEM lamellas.

4.
Opt Lett ; 37(22): 4588-90, 2012 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-23164847

RESUMO

We report the design and optical characterization of fully suspended wire waveguides and photonic crystal (PhC) membranes fabricated on a gallium nitride layer grown on silicon substrate operating at 1.5 µm. W1-type PhC waveguides are coupled with suspended wires and are investigated using a standard end-fire setup. The experimental and theoretical dispersion properties of the propagating modes in the wires and photonic-crystal waveguides are shown. Modified L3 cavities with quality factors of up to 2200 and heterostructure cavities with quality factors of up to 5400 are experimentally demonstrated.

5.
Nat Commun ; 12(1): 3504, 2021 Jun 09.
Artigo em Inglês | MEDLINE | ID: mdl-34108471

RESUMO

Ultrafast nonlinear photonics enables a host of applications in advanced on-chip spectroscopy and information processing. These rely on a strong intensity dependent (nonlinear) refractive index capable of modulating optical pulses on sub-picosecond timescales and on length scales suitable for integrated photonics. Currently there is no platform that can provide this for the UV spectral range where broadband spectra generated by nonlinear modulation can pave the way to new on-chip ultrafast (bio-) chemical spectroscopy devices. We demonstrate the giant nonlinearity of UV hybrid light-matter states (exciton-polaritons) up to room temperature in an AlInGaN waveguide. We experimentally measure ultrafast nonlinear spectral broadening of UV pulses in a compact 100 µm long device and deduce a nonlinearity 1000 times that in common UV nonlinear materials and comparable to non-UV polariton devices. Our demonstration promises to underpin a new generation of integrated UV nonlinear light sources for advanced spectroscopy and measurement.

6.
Phys Rev Lett ; 104(16): 166402, 2010 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-20482070

RESUMO

A room temperature polariton condensate realized in a microcavity with embedded GaN quantum wells emits linearly polarized light at threshold with the plane of polarization pinned to one of the crystallographic axes. With increasing pumping power, a depinning of the polarization is observed resulting in a progressive decrease of the polarization degree of the emitted light. This depinning is understood in terms of polariton-polariton repulsion competing with the static disorder potential effect. The polarization behavior differs from that of conventional lasers where the polarization degree usually increases as a function of pumping power.

7.
J Nanosci Nanotechnol ; 10(4): 2473-8, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20355450

RESUMO

GaN/AIN structures made of GaN quantum dots (QDs) separated by AIN spacer layers, were doped with Europium by ion implantation. Rutherford Backscattering/Channelling measurements showed that Eu is incorporated mainly on near-substitutional cation sites within the superlattice region. Only slight deterioration of the crystal quality and no intermixing of the different layers are observed after implantation and annealing. After thermal annealing, photoluminescence associated with Eu3+ ions was observed. From its behaviour under different photon energy excitation and sample temperature we concluded that the Eu-related emitting centres are located inside the GaN QDs or dispersed in the GaN and AIN buffer or spacer layers. The 624 nm PL line, associated with Eu-doped GaN QDs, shows very low thermal quenching, suggesting recombination of confined carriers through rare-earth ion excitation.

8.
Ultrasound Med Biol ; Suppl 2: 289-92, 1983.
Artigo em Inglês | MEDLINE | ID: mdl-6545734

RESUMO

This is a two-phase study. The first phase assesses the use of portable 2D echocardiography for diagnostic studies in remote areas. The second phase examines the diagnostic capabilities of 2D "only" versus 2D echocardiography combined with M-mode.


Assuntos
Ecocardiografia/métodos , Cardiopatias/diagnóstico , Ecocardiografia/economia , Estudos de Avaliação como Assunto , Reações Falso-Negativas , Humanos , População Rural
9.
J Health Soc Behav ; 36(2): 195-212, 1995 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-9113143

RESUMO

We apply the Health Belief Model (HBM) and the Theory of Reasoned Action (TRA) to an analysis of unsafe sexual practices (inconsistent condom use with commercial sex workers) among men living in a high HIV-prevalence area. The empirical analysis is based primarily on a survey of sexual practices that was conducted by the authors during the fall of 1991. The survey sample includes university undergraduates, soldiers, clerks, and laborers living in Chiang Mai, Thailand. There is much overlap between the two theories, and both provide useful frameworks for examining condom use in this population. However, the Bayes Information Criterion (BIC) approach provides very strong evidence that TRA is the more plausible model, given the data. The success of TRA appears to be due to its more adequate incorporation of peer group effects. Other covariates positively associated with consistent condom use in the multivariate models include knowledge about the consequences of HIV infection, knowledge about the benefits of condom use for preventing infection, and positive attitudes about condoms.


Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Homens/psicologia , Modelos Psicológicos , Assunção de Riscos , Comportamento Sexual , Adulto , Infecções por HIV/prevenção & controle , Humanos , Masculino , Análise Multivariada , Reprodutibilidade dos Testes , Inquéritos e Questionários , Tailândia
10.
Phys Rev Lett ; 70(7): 1031, 1993 Feb 15.
Artigo em Inglês | MEDLINE | ID: mdl-10054267
13.
Phys Rev B Condens Matter ; 53(20): R13231-R13234, 1996 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-9983154
14.
Phys Rev B Condens Matter ; 48(11): 8502-8505, 1993 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-10007060
19.
Phys Rev Lett ; 101(13): 136409, 2008 Sep 26.
Artigo em Inglês | MEDLINE | ID: mdl-18851475

RESUMO

We observe the buildup of strong (approximately 50%) spontaneous vector polarization in emission from a GaN-based polariton laser excited by short optical pulses at room temperature. The Stokes vector of emitted light changes its orientation randomly from one excitation pulse to another, so that the time-integrated polarization remains zero. This behavior is completely different from any previous laser. We interpret this observation in terms of the spontaneous symmetry breaking in a Bose-Einstein condensate of exciton polaritons.

20.
Phys Rev Lett ; 98(12): 126405, 2007 Mar 23.
Artigo em Inglês | MEDLINE | ID: mdl-17501142

RESUMO

We observe a room-temperature low-threshold transition to a coherent polariton state in bulk GaN microcavities in the strong-coupling regime. Nonresonant pulsed optical pumping produces rapid thermalization and yields a clear emission threshold of 1 mW, corresponding to an absorbed energy density of 29 microJ cm-2, 1 order of magnitude smaller than the best optically pumped (In,Ga)N quantum-well surface-emitting lasers (VCSELs). Angular and spectrally resolved luminescence show that the polariton emission is beamed in the normal direction with an angular width of +/-5 degrees and spatial size around 5 microm.

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