Detalhe da pesquisa
1.
Synthesis, carbonic anhydrase inhibition studies and modelling investigations of phthalimide-hydantoin hybrids.
J Enzyme Inhib Med Chem
; 39(1): 2335927, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38606915
2.
Benzothiadiazinone-1,1-Dioxide Carbonic Anhydrase Inhibitors Suppress the Growth of Drug-Resistant Mycobacterium tuberculosis Strains.
Int J Mol Sci
; 25(5)2024 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38473830
3.
Leveraging SARS-CoV-2 Main Protease (Mpro) for COVID-19 Mitigation with Selenium-Based Inhibitors.
Int J Mol Sci
; 25(2)2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38256046
4.
Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies.
Bioorg Med Chem
; 94: 117467, 2023 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37722299
5.
Discovery of the first-in-class potent and isoform-selective human carbonic anhydrase III inhibitors.
J Enzyme Inhib Med Chem
; 38(1): 2202360, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37092262
6.
Selenium-analogs based on natural sources as cancer-associated carbonic anhydrase isoforms IX and XII inhibitors.
J Enzyme Inhib Med Chem
; 38(1): 2191165, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36938694
7.
Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights.
J Enzyme Inhib Med Chem
; 38(1): 2201407, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37078173
8.
Exploration of 3-aryl pyrazole-tethered sulfamoyl carboxamides as carbonic anhydrase inhibitors.
Arch Pharm (Weinheim)
; 356(11): e2300309, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37691073
9.
Inhibition Studies on Human and Mycobacterial Carbonic Anhydrases with N-((4-Sulfamoylphenyl)carbamothioyl) Amides.
Molecules
; 28(10)2023 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37241761
10.
Calixarenes Incorporating Sulfonamide Moieties: Versatile Ligands for Carbonic Anhydrases Inhibition.
Chemistry
; 28(6): e202103527, 2022 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34882858
11.
Pharmaceutical strategies for preventing toxicity and promoting antioxidant and anti-inflammatory actions of bilirubin.
J Enzyme Inhib Med Chem
; 37(1): 487-501, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34986721
12.
The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII.
J Enzyme Inhib Med Chem
; 37(1): 930-939, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35306936
13.
Novel benzenesulfonamide-bearing pyrazoles and 1,2,4-thiadiazoles as selective carbonic anhydrase inhibitors.
Arch Pharm (Weinheim)
; 355(1): e2100241, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34596922
14.
Probing the Efficiency of 13-Pyridylalkyl Berberine Derivatives to Human Telomeric G-Quadruplexes Binding: Spectroscopic, Solid State and In Silico Analysis.
Int J Mol Sci
; 23(22)2022 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430540
15.
Inhibition of α-, ß- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae with aromatic sulphonamides and clinically licenced drugs - a joint docking/molecular dynamics study.
J Enzyme Inhib Med Chem
; 36(1): 469-479, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33472446
16.
Selective Inhibition of Helicobacter pylori Carbonic Anhydrases by Carvacrol and Thymol Could Impair Biofilm Production and the Release of Outer Membrane Vesicles.
Int J Mol Sci
; 22(21)2021 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769015
17.
Perfluoroalkyl Substances of Significant Environmental Concern Can Strongly Inhibit Human Carbonic Anhydrase Isozymes.
Anal Chem
; 92(6): 4614-4622, 2020 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32096628
18.
The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors.
J Enzyme Inhib Med Chem
; 35(1): 1011-1020, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32297543
19.
Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation.
J Enzyme Inhib Med Chem
; 35(1): 1891-1905, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33003975
20.
Aryl-4,5-dihydro-1H-pyrazole-1-carboxamide Derivatives Bearing a Sulfonamide Moiety Show Single-digit Nanomolar-to-Subnanomolar Inhibition Constants against the Tumor-associated Human Carbonic Anhydrases IX and XII.
Int J Mol Sci
; 21(7)2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283813