Detalhe da pesquisa
1.
Cholinergic signaling at the body wall neuromuscular junction distally inhibits feeding behavior in Caenorhabditis elegans.
J Biol Chem
; 298(1): 101466, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34864060
2.
Influence of experimental end point on the therapeutic efficacy of the antinicotinic compounds MB408, MB442 and MB444 in treating nerve agent poisoned mice - a comparison with oxime-based treatment.
Toxicol Mech Methods
; 30(9): 703-710, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32878547
3.
Multiple metabolic pathways are predictive of ricin intoxication in a rat model.
Metabolomics
; 15(7): 102, 2019 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31270703
4.
Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology.
J Immunol
; 198(10): 3989-3998, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28320831
5.
An imaging flow cytometry method to assess ricin trafficking in A549 human lung epithelial cells.
Methods
; 134-135: 41-49, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29122725
6.
Evaluation of the benefit of the bispyridinium compound MB327 for the antidotal treatment of nerve agent-poisoned mice.
Toxicol Mech Methods
; 26(5): 334-9, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27097774
7.
Restoration of nerve agent impaired neuromuscular transmission in rat diaphragm by bispyridinium non-oximes - Structure-activity relationships.
Toxicology
; 503: 153741, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38311098
8.
The use of bispyridinium non-oxime analogues for the restoration of nerve agent impaired neuromuscular transmission in rat hemidiaphragms - Structure optimization.
Toxicol Lett
; 397: 42-47, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38723915
9.
Comparative Aspects of Ricin Toxicity by Inhalation.
Toxins (Basel)
; 15(4)2023 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37104219
10.
Modelling organophosphate intoxication in C. elegans highlights nicotinic acetylcholine receptor determinants that mitigate poisoning.
PLoS One
; 18(4): e0284786, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37083685
11.
From "crisis to recovery": A complete insight into the mechanisms of chlorine injury in the lung.
Life Sci
; 312: 121252, 2023 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36460096
12.
Influence of Experimental End Point on the Therapeutic Efficacy of Essential and Additional Antidotes in Organophosphorus Nerve Agent-Intoxicated Mice.
Toxics
; 10(4)2022 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35448453
13.
C. elegans pharyngeal pumping provides a whole organism bio-assay to investigate anti-cholinesterase intoxication and antidotes.
Neurotoxicology
; 82: 50-62, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33176172
14.
Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR.
Toxicol Lett
; 340: 114-122, 2021 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33482275
15.
Establishment of a Novel Oral Murine Model of Ricin Intoxication and Efficacy Assessment of Ovine Ricin Antitoxins.
Toxins (Basel)
; 12(12)2020 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33302573
16.
Assessment of false transmitters as treatments for nerve agent poisoning.
Toxicol Lett
; 321: 21-31, 2020 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31830555
17.
3-Quinuclidinyl-α-methoxydiphenylacetate: A multi-targeted ligand with antimuscarinic and antinicotinic effects designed for the treatment of anticholinesterase poisoning.
Toxicol Lett
; 325: 67-76, 2020 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32017982
18.
Some benefit from non-oximes MB408, MB442 and MB444 in combination with the oximes HI-6 or obidoxime and atropine in antidoting sarin or cyclosarin poisoned mice.
Toxicology
; 408: 95-100, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30005893
19.
Evaluation of the Influence of Three Newly Developed Bispyridinium Anti-nicotinic Compounds (MB408, MB442, MB444) on the Efficacy of Antidotal Treatment of Nerve Agent Poisoning in Mice.
Basic Clin Pharmacol Toxicol
; 122(4): 429-435, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29117635
20.
Production, Characterisation and Testing of an Ovine Antitoxin against Ricin; Efficacy, Potency and Mechanisms of Action.
Toxins (Basel)
; 9(10)2017 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29057798