Detalhe da pesquisa
1.
Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib.
Mol Cell Biol
; 26(16): 6082-93, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16880519
2.
The dynamic behavior of CheW from Thermotoga maritima in solution, as determined by nuclear magnetic resonance: implications for potential protein-protein interaction sites.
Biophys Chem
; 101-102: 359-73, 2002 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12488014
3.
A specific need for CRKL in p210BCR-ABL-induced transformation of mouse hematopoietic progenitors.
Cancer Res
; 70(18): 7325-35, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20807813
4.
A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice.
PLoS One
; 4(10): e7439, 2009 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19823681
5.
In vitro and in vivo activity of ATP-based kinase inhibitors AP23464 and AP23848 against activation-loop mutants of Kit.
Blood
; 106(1): 227-34, 2005 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15746079
6.
The solution structure and interactions of CheW from Thermotoga maritima.
Nat Struct Biol
; 9(2): 121-5, 2002 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-11799399
7.
Sensitivity of oncogenic KIT mutants to the kinase inhibitors MLN518 and PD180970.
Blood
; 104(12): 3754-7, 2004 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15304388
8.
Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis.
Blood
; 104(9): 2912-8, 2004 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15242881
9.
Bigger is better: megadalton protein NMR in solution.
Nat Struct Biol
; 9(8): 567-8, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12145644