Detalhe da pesquisa
1.
Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation.
Nat Immunol
; 22(6): 711-722, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34017121
2.
Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis.
N Engl J Med
; 382(19): 1811-1822, 2020 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32374962
3.
Efficacy and safety of emapalumab in macrophage activation syndrome.
Ann Rheum Dis
; 82(6): 857-865, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37001971
4.
The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS).
Ann Rheum Dis
; 82(10): 1271-1285, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37487610
5.
Monocyte and bone marrow macrophage transcriptional phenotypes in systemic juvenile idiopathic arthritis reveal TRIM8 as a mediator of IFN-γ hyper-responsiveness and risk for macrophage activation syndrome.
Ann Rheum Dis
; 80(5): 617-625, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33277241
6.
A Multiparameter Flow Cytometry Analysis Panel to Assess CD163 mRNA and Protein in Monocyte and Macrophage Populations in Hyperinflammatory Diseases.
J Immunol
; 202(5): 1635-1643, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30683706
7.
Synergistic Signaling of TLR and IFNα/ß Facilitates Escape of IL-18 Expression from Endotoxin Tolerance.
Am J Respir Crit Care Med
; 201(5): 526-539, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31710506
8.
IL-18 as a biomarker linking systemic juvenile idiopathic arthritis and macrophage activation syndrome.
Rheumatology (Oxford)
; 59(2): 361-366, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31326996
9.
Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.
Blood
; 131(13): 1442-1455, 2018 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29326099
10.
Emergent high fatality lung disease in systemic juvenile arthritis.
Ann Rheum Dis
; 78(12): 1722-1731, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31562126
11.
Neutralization of IFN-γ reverts clinical and laboratory features in a mouse model of macrophage activation syndrome.
J Allergy Clin Immunol
; 141(4): 1439-1449, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28807602
12.
A Heterozygous RAB27A Mutation Associated with Delayed Cytolytic Granule Polarization and Hemophagocytic Lymphohistiocytosis.
J Immunol
; 196(6): 2492-503, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26880764
13.
HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis.
Proc Natl Acad Sci U S A
; 112(52): 15970-5, 2015 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26598658
14.
Pathogenesis of macrophage activation syndrome and potential for cytokine- directed therapies.
Annu Rev Med
; 66: 145-59, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25386930
15.
Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
Ann Rheum Dis
; 76(1): 166-172, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27296321
16.
Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.
Ann Rheum Dis
; 76(5): 906-913, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27927641
17.
Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate.
Rheumatology (Oxford)
; 56(9): 1542-1551, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28582527
18.
Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza.
J Infect Dis
; 213(7): 1180-8, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26597256
19.
Janus kinase (JAK) inhibition with baricitinib in refractory juvenile dermatomyositis.
Ann Rheum Dis
; 80(3): 406-408, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32843325
20.
2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative.
Ann Rheum Dis
; 75(3): 481-9, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26865703