Detalhe da pesquisa
1.
Identification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin-Like Phospholipase Domain Containing 3-Mediated Acceleration of Steatohepatitis.
Hepatology
; 73(4): 1290-1306, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33131062
2.
Physiological Expression of AMPKγ2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice.
J Biol Chem
; 291(45): 23428-23439, 2016 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27621313
3.
Glucagon receptor antagonism induces increased cholesterol absorption.
J Lipid Res
; 56(11): 2183-95, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26373568
4.
Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice.
J Lipid Res
; 54(10): 2615-22, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23828778
5.
Learn from failures and stay hopeful to GPR40, a GPCR target with robust efficacy, for therapy of metabolic disorders.
Front Pharmacol
; 13: 1043828, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36386134
6.
A futile metabolic cycle activated in adipocytes by antidiabetic agents.
Nat Med
; 8(10): 1122-8, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12357248
7.
Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRalpha.
Cell Metab
; 1(5): 297-308, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16054077
8.
Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver.
PLoS One
; 14(2): e0211568, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30811418
9.
PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1.
J Clin Invest
; 115(8): 2244-56, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16007265
10.
Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.
ACS Med Chem Lett
; 9(1): 39-44, 2018 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29348809
11.
Correction: The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys.
PLoS One
; 12(1): e0170721, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28103304
12.
Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy.
Science
; 357(6350): 507-511, 2017 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28705990
13.
The Fatty Acid Synthase Inhibitor Platensimycin Improves Insulin Resistance without Inducing Liver Steatosis in Mice and Monkeys.
PLoS One
; 11(10): e0164133, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27695056
14.
Factors affecting insulin-regulated hepatic gene expression.
Prog Mol Biol Transl Sci
; 121: 165-215, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24373238
15.
Accelerated fatty acid oxidation in muscle averts fasting-induced hepatic steatosis in SJL/J mice.
J Biol Chem
; 284(36): 24644-52, 2009 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19581301
16.
PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.
Am J Physiol Endocrinol Metab
; 293(6): E1736-45, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17848638
17.
Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.
Genes Dev
; 19(4): 453-61, 2005 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15681609
18.
Synphilin in normal human brains and in synucleinopathies: studies with new antibodies.
Acta Neuropathol
; 105(2): 177-84, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12536229