1.
Boll Chim Farm
; 138(1): 30-3, 1999 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10326313
RESUMO
4-Oxy as well as 4-thio-5-carboxy and 5-hydroxy pyrimidine derivatives were synthesized and their microbiological properties were compared.
Assuntos
Antibacterianos/síntese química , Pirimidinas/síntese química , Antibacterianos/farmacologia , Bactérias/efeitos dos fármacos , Espectroscopia de Ressonância Magnética , Testes de Sensibilidade Microbiana , Pirimidinas/farmacologia
2.
Boll Chim Farm
; 142(4): 146-50, 2003 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12918222
RESUMO
This paper describes the synthesis of 4,5-diaminoderivatives of pyrimidine and pyrimido [4,5-d] pyrimidines and evaluation of their antibacterial activity on 9 selected bacterial species relatif the changes in the chemical structure to an increase in the bioactive properties.