1.
Indian J Hematol Blood Transfus
; 32(Suppl 1): 66-8, 2016 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27408358
RESUMO
Klinefelter syndrome (KS) is a chromosome abnormality characterized by a 47, XXY karyotype associated with hypogonadism and infertility. We present two cases of leukemia in patients with KS. The first patient presented with acute promyelocytic leukemia. He relapsed after the end of treatment. The second patient was diagnosed with chronic myeloid leukemia. Treatment with imatinib failed and the patient presented with myeloid blast crisis.