Detalhe da pesquisa
1.
Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques.
Toxicol Pathol
; 50(4): 415-431, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35658751
2.
Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms.
J Immunol
; 205(3): 648-660, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32591390
3.
In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus.
Mol Ther
; 27(5): 974-985, 2019 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962164
4.
Deficiency of the purine metabolic gene HPRT dysregulates microRNA-17 family cluster and guanine-based cellular functions: a role for EPAC in Lesch-Nyhan syndrome.
Hum Mol Genet
; 22(22): 4502-15, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23804752
5.
MicroRNA-mediated dysregulation of neural developmental genes in HPRT deficiency: clues for Lesch-Nyhan disease?
Hum Mol Genet
; 21(3): 609-22, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22042773
6.
Prenatal AAV9-GFP administration in fetal lambs results in transduction of female germ cells and maternal exposure to virus.
Mol Ther Methods Clin Dev
; 32(2): 101263, 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38827250
7.
Deficiency of the housekeeping gene hypoxanthine-guanine phosphoribosyltransferase (HPRT) dysregulates neurogenesis.
Mol Ther
; 18(1): 54-62, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19672249
8.
Protection against Borreliella burgdorferi infection mediated by a synthetically engineered DNA vaccine.
Hum Vaccin Immunother
; 16(9): 2114-2122, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32783701
9.
Characterization of the gene delivery properties of baculoviral-based virosomal vectors.
J Virol Methods
; 148(1-2): 277-82, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18207578
10.
Factors associated with induced chronic inflammation in mdx skeletal muscle cause posttranslational stabilization and augmentation of extrasynaptic sarcolemmal utrophin.
Hum Gene Ther
; 16(4): 489-501, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15871680
11.
MicroRNAs: tools of mechanistic insights and biological therapeutics discovery for the rare neurogenetic syndrome Lesch-Nyhan disease (LND).
Adv Genet
; 90: 103-131, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26296934
12.
Striatal neurodevelopment is dysregulated in purine metabolism deficiency and impacts DARPP-32, BDNF/TrkB expression and signaling: new insights on the molecular and cellular basis of Lesch-Nyhan Syndrome.
PLoS One
; 9(5): e96575, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24804781
13.
HPRT-deficiency dysregulates cAMP-PKA signaling and phosphodiesterase 10A expression: mechanistic insight and potential target for Lesch-Nyhan Disease?
PLoS One
; 8(5): e63333, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23691025
14.
HPRT deficiency coordinately dysregulates canonical Wnt and presenilin-1 signaling: a neuro-developmental regulatory role for a housekeeping gene?
PLoS One
; 6(1): e16572, 2011 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21305049
15.
Preparation of pseudotyped lentiviral vectors resistant to inactivation by serum complement.
Cold Spring Harb Protoc
; 2010(7): pdb.prot5420, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20647353
16.
Baculovirus GP64-pseudotyped HIV-based lentivirus vectors are stabilized against complement inactivation by codisplay of decay accelerating factor (DAF) or of a GP64-DAF fusion protein.
Mol Ther
; 11(4): 645-51, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15771967
17.
Regenerative capacity of the dystrophic (mdx) diaphragm after induced injury.
Am J Physiol Regul Integr Comp Physiol
; 287(4): R961-8, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15191902
18.
Cell surface heparan sulfate is a receptor for attachment of envelope protein-free retrovirus-like particles and VSV-G pseudotyped MLV-derived retrovirus vectors to target cells.
Mol Ther
; 5(5 Pt 1): 538-46, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-11991744
19.
Ligand-modified vesicular stomatitis virus glycoprotein displays a temperature-sensitive intracellular trafficking and virus assembly phenotype.
Mol Ther
; 9(1): 76-84, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14741780