Detalhe da pesquisa
1.
N-Glycosylation and enzymatic activity of the rHuPH20 expressed in Chinese hamster ovary cells.
Anal Biochem
; 632: 114380, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34520755
2.
Therapeutic efficacy of an anti-PD-L1 antibody based immunocytokine in a metastatic mouse model of colorectal cancer.
Biochem Biophys Res Commun
; 480(2): 160-165, 2016 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27720718
3.
In-Depth Characterization of a Pro-Antibody-Drug Conjugate by LC-MS.
Mol Pharm
; 13(8): 2702-10, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27377124
4.
Quantitative analysis of histone H3 and H4 post-translational modifications in doxorubicin-resistant leukemia cells.
Biomed Chromatogr
; 30(4): 638-44, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26317407
5.
Structural basis for treating tumor necrosis factor α (TNFα)-associated diseases with the therapeutic antibody infliximab.
J Biol Chem
; 288(19): 13799-807, 2013 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23504311
6.
Comparison of the inhibition mechanisms of adalimumab and infliximab in treating tumor necrosis factor α-associated diseases from a molecular view.
J Biol Chem
; 288(38): 27059-27067, 2013 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23943614
7.
Development of a reliable cell-based reporter gene assay to measure the bioactivity of anti-HER2 therapeutic antibodies.
J Pharm Biomed Anal
; 245: 116185, 2024 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38723556
8.
Highly drug/target-tolerant neutralizing antibody (NAb) assay development through target-based drug depletion and drug-based NAb extraction for an anti-EGFR therapeutic monoclonal antibody.
J Pharm Biomed Anal
; 241: 116006, 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38309099
9.
Improving product quality and productivity of an antibody-based biotherapeutic using inverted frustoconical shaking bioreactors.
Front Bioeng Biotechnol
; 12: 1352098, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38585708
10.
A Randomized, Single-dose, Phase I Clinical Comparison of a Trastuzumab Biosimilar With a Reference Trastuzumab Formulation in Healthy Chinese Male Volunteers.
Clin Pharmacol Drug Dev
; 12(2): 181-189, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36317757
11.
Population Pharmacokinetics of CMAB008 (an Infliximab Biosimilar) and Remicade® in Healthy Subjects and Patients with Moderately to Severely Active Rheumatoid Arthritis.
Adv Ther
; 40(3): 1005-1018, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36607544
12.
Dual blockade of CD47 and CD24 signaling using a novel bispecific antibody fusion protein enhances macrophage immunotherapy.
Mol Ther Oncolytics
; 31: 100747, 2023 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38046893
13.
Identification of a novel functional domain of ricin responsible for its potent toxicity.
J Biol Chem
; 286(14): 12166-71, 2011 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21303906
14.
Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab.
J Immunol
; 184(3): 1361-8, 2010 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20032294
15.
Identification, Efficacy, and Stability Evaluation of Succinimide Modification With a High Abundance in the Framework Region of Golimumab.
Front Chem
; 10: 826923, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35449588
16.
A Randomized, Double-Blind, Parallel Controlled, Single-Dose Phase I Study Comparing the Pharmacokinetics, Safety, and Immunogenicity of the Infliximab Biosimilar CMAB008 and the Reference Product in Healthy Chinese Male Subjects.
Clin Pharmacol Drug Dev
; 11(9): 1028-1035, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35778977
17.
Mass spectrometry-based multi-attribute method for mutation analysis in the early development of therapeutic proteins.
J Pharm Biomed Anal
; 220: 115018, 2022 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36030755
18.
The protein-protein interface evolution acts in a similar way to antibody affinity maturation.
J Biol Chem
; 285(6): 3865-3871, 2010 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20007707
19.
Increased expression of iASPP, regulated by hepatitis B virus X protein-mediated NF-κB activation, in hepatocellular carcinoma.
Gastroenterology
; 139(6): 2183-2194.e5, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20600029
20.
Characterization of a rituximab variant with potent antitumor activity against rituximab-resistant B-cell lymphoma.
Blood
; 114(24): 5007-15, 2009 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19828699