Detalhe da pesquisa
1.
In vivo CRISPR editing with no detectable genome-wide off-target mutations.
Nature
; 561(7723): 416-419, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30209390
2.
Analysis of off-target effects in CRISPR-based gene drives in the human malaria mosquito.
Proc Natl Acad Sci U S A
; 118(22)2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050017
3.
Therapeutic avenues for cancer neuroscience: translational frontiers and clinical opportunities.
Lancet Oncol
; 23(2): e62-e74, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35114133
4.
Activities and specificities of CRISPR/Cas9 and Cas12a nucleases for targeted mutagenesis in maize.
Plant Biotechnol J
; 17(2): 362-372, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29972722
5.
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data.
Nat Methods
; 15(12): 992-993, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30504875
6.
Precise DNA cleavage using CRISPR-SpRYgests.
Nat Biotechnol
; 41(3): 409-416, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36203014
7.
Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis.
bioRxiv
; 2023 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37425692
8.
DNA repair and immune checkpoint blockade response.
Cancer Genet
; 264-265: 1-4, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35245846
9.
Treatment-associated remodeling of the pancreatic cancer endothelium at single-cell resolution.
Front Oncol
; 12: 929950, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36185212
10.
Genomic alterations predictive of poor clinical outcomes in pan-cancer.
Oncotarget
; 13: 1069-1077, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36187555
11.
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment.
Nat Genet
; 54(8): 1178-1191, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35902743
12.
Pan-Cancer Survival Classification With Clinicopathological and Targeted Gene Expression Features.
Cancer Inform
; 20: 11769351211035137, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34376966
13.
Refining the Molecular Framework for Pancreatic Cancer with Single-cell and Spatial Technologies.
Clin Cancer Res
; 27(14): 3825-3833, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33653818
14.
Pan-cancer Transcriptomic Predictors of Perineural Invasion Improve Occult Histopathologic Detection.
Clin Cancer Res
; 27(10): 2807-2815, 2021 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33632928
15.
Novel genomic signature predictive of response to immune checkpoint blockade: A pan-cancer analysis from project Genomics Evidence Neo-plasia Information Exchange (GENIE).
Cancer Genet
; 258-259: 61-68, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34551377
16.
Defining CRISPR-Cas9 genome-wide nuclease activities with CIRCLE-seq.
Nat Protoc
; 13(11): 2615-2642, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30341435
17.
Racial Differences in Genomic Profiles of Breast Cancer.
JAMA Netw Open
; 5(3): e220573, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35230441
18.
Silver Linings: An Opportunity to Improve Clinical Paradigms After the COVID-19 Pandemic.
JCO Oncol Pract
; 16(9): 532-534, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32469687