1.
Anal Biochem
; 592: 113573, 2020 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31899191
RESUMO
In consideration of the strong oxidizing power of hypochlorite (ClO-), which could cleave CN moiety, a cyclometalated iridium (III) complex (Ir-Ts) modified hydrazide group as the response unit was synthesized to sensitively and selectively detect ClO- under neutral condition. Upon addition of ClO-, a 21-fold emission enhancement at 574 nm was observed and phosphorescent product was formed due to the cleavage of CN moiety. The probe Ir-Ts displayed rapid response (<15 s) and high selectivity toward ClO- with a low detection limit of 86 nM. More importantly, bioimaging of ClO- was further studied in living cells.