Detalhe da pesquisa
1.
The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation.
Cell
; 134(3): 496-507, 2008 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18692472
2.
Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population.
Blood
; 129(21): 2882-2895, 2017 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283481
3.
Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML.
Blood
; 125(18): 2815-24, 2015 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25736313
4.
Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival.
PLoS Biol
; 11(3): e1001515, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23526884
5.
Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription.
Blood
; 122(5): 738-48, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23775716
6.
Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9.
Bioorg Med Chem
; 23(19): 6280-96, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26349627
7.
Phosphorylation of serine 779 in fibroblast growth factor receptor 1 and 2 by protein kinase C(epsilon) regulates Ras/mitogen-activated protein kinase signaling and neuronal differentiation.
J Biol Chem
; 288(21): 14874-85, 2013 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23564461
8.
New insights into the nutritional genomics of adult-onset riboflavin-responsive diseases.
Nutr Metab (Lond)
; 20(1): 42, 2023 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37845732
9.
The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.
Blood
; 114(7): 1289-98, 2009 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19436055
10.
Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML.
Blood
; 114(23): 4859-70, 2009 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19805619
11.
Molecular basis of cytokine receptor activation.
IUBMB Life
; 62(7): 509-18, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20540154
12.
A sensitive magnetic bead method for the detection and identification of tyrosine phosphorylation in proteins by MALDI-TOF/TOF MS.
Proteomics
; 9(11): 3047-57, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19526547
13.
Meeting report: Barossa 2005--Signaling Networks.
Sci STKE
; 2006(324): pe9, 2006 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16507819
14.
Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.
Oncotarget
; 7(30): 47465-47478, 2016 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27329844
15.
Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.
Cancer Cell
; 29(2): 145-58, 2016 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26859455
16.
14-3-3ζ coordinates adipogenesis of visceral fat.
Nat Commun
; 6: 7671, 2015 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26220403
17.
Oncogenic mutations of p110α isoform of PI 3-kinase upregulate its protein kinase activity.
PLoS One
; 8(8): e71337, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23936502
18.
Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics.
Cancer Cell
; 30(3): 499-500, 2016 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27622337
19.
Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers.
Cancer Res
; 70(13): 5438-47, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20551067
20.
14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival.
J Biol Chem
; 284(18): 12080-90, 2009 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19218246