Detalhe da pesquisa
1.
Similarly efficacious anti-malarial drugs SJ733 and pyronaridine differ in their ability to remove circulating parasites in mice.
Malar J
; 21(1): 49, 2022 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35172826
2.
Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones.
Malar J
; 20(1): 107, 2021 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33608015
3.
Identification of Plasmodium falciparum heat shock 90 inhibitors via molecular docking.
Bioorg Med Chem Lett
; 35: 127818, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33513390
4.
Antimalarial activity of 2,6-dibenzylidenecyclohexanone derivatives.
Bioorg Med Chem Lett
; 47: 128216, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157390
5.
Phenotypic Screens Reveal Posaconazole as a Rapidly Acting Amebicidal Combination Partner for Treatment of Primary Amoebic Meningoencephalitis.
J Infect Dis
; 219(7): 1095-1103, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30358879
6.
A small diversity library of α-methyl amide analogs of sulindac for probing anticancer structure-activity relationships.
Bioorg Med Chem Lett
; 28(12): 2136-2142, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29776741
7.
Shared Consensus Machine Learning Models for Predicting Blood Stage Malaria Inhibition.
J Chem Inf Model
; 57(3): 445-453, 2017 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28257198
8.
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.
Proc Natl Acad Sci U S A
; 111(50): E5455-62, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453091
9.
Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes.
J Antimicrob Chemother
; 71(4): 956-63, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26682963
10.
Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum.
Malar J
; 15(1): 270, 2016 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27165106
11.
Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic ß-hairpins.
Org Biomol Chem
; 14(44): 10386-10393, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27731454
12.
Chemical genetics of Plasmodium falciparum.
Nature
; 465(7296): 311-5, 2010 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20485428
13.
Potent Plasmodium falciparum gametocytocidal activity of diaminonaphthoquinones, lead antimalarial chemotypes identified in an antimalarial compound screen.
Antimicrob Agents Chemother
; 59(3): 1389-97, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25512421
14.
Evaluation of histone deacetylase inhibitors (HDACi) as therapeutic leads for human African trypanosomiasis (HAT).
Bioorg Med Chem
; 23(16): 5151-5, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25637120
15.
LC-MS- and (1)H NMR Spectroscopy-Guided Identification of Antifungal Diterpenoids from Sagittaria latifolia.
J Nat Prod
; 78(9): 2255-9, 2015 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26371504
16.
Dihydroquinazolinone inhibitors of proliferation of blood and liver stage malaria parasites.
Antimicrob Agents Chemother
; 58(3): 1516-22, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24366746
17.
Treatment of murine cerebral malaria by artemisone in combination with conventional antimalarial drugs: antiplasmodial effects and immune responses.
Antimicrob Agents Chemother
; 58(8): 4745-54, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24913162
18.
Repositioning: the fast track to new anti-malarial medicines?
Malar J
; 13: 143, 2014 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24731288
19.
Organocatalytic, diastereo- and enantioselective synthesis of nonsymmetric cis-stilbene diamines: a platform for the preparation of single-enantiomer cis-imidazolines for protein-protein inhibition.
J Org Chem
; 79(15): 6913-38, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25017623
20.
Pharmacokinetics and efficacy of the spleen tyrosine kinase inhibitor r406 after ocular delivery for retinoblastoma.
Pharm Res
; 31(11): 3060-72, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24906597