Analysis of scientific output by spine surgeons from Japan: January 2000 to December 2013.

BACKGROUND: Over the last decade, the growing body of work on spine pathology has led to developments and refinements in the areas of basic science, diagnosis and treatment of a variety of spine conditions. Scientific publications have a global impact on the international scientific community as they share vital information that can be applied by physicians worldwide to solve their everyday medical problems. The historical background of scientific publication in journals in Japan on the subject of spine is unclear. METHODS: We performed a literature search for publications by Japanese spine surgeons regarding spine or spinal cord topics using an online database: Pubmed.gov (http://www.ncbi.nlm.nih.gov/pubmed/). The results were stored and analyzed at the Laboratory of Clinical Studies and Basic Models of Spinal Disorders of the University of Caxias do Sul. Results were limited to articles published from January 2000 to December 2013. The search terms used were "Japan" AND ("spine" OR "spinal diseases" OR "spinal cord" OR "spinal cord diseases" OR "vertebroplasty" OR "arthrodesis" OR "discectomy" OR "foraminotomy" OR "laminectomy" OR "denervation" OR "back injuries"). Japanese spine surgeons were defined as spine surgeons from orthopedic or neurosurgical specialties where the publication was affiliated with Japanese services. RESULTS: A total of 16,140 articles were identified by the Medline search. Most of the articles were excluded based on information provided in the title and abstract as they were not related to spine surgery. This study comprised 1768 articles published in the Medline database by Japanese spine surgeons from 2000 to 2013. The number of publications rose in a linear fashion, with the number of papers published increasing by 5.4 per year (p = 0.038). In recent years the publications were increasingly performed in conjunction with the neurosurgery and orthopedics specialties. CONCLUSIONS: This study showed a clear increase in publications (on Medline) by Japanese spine surgeons over the last 14 years. While this is a positive development, there is also cause for concern as there is some evidence that the number of young scientists is declining in Japan. Special attention to educating researchers and improving resources for research is crucial to further increase the number and quality of Japanese publications.

Strategy to increase research in Latin America: project on education in research by AOSpine Latin America.

BACKGROUND: The emancipatory nature of education requires research as its fundamental base, because physicians can only improve their skills and knowledge through enquiry. The number and quality of scientific publications by Latin-American spine surgeons found in the Medline database was low between 2000 and 2011. Nevertheless, the research Bank Survey of AOSpine Latin America (AOSLA) members showed that 96% of responders were very interested and motivated to perform scientific research. METHODS AND POPULATION: The research officer of AOSLA together with the Country Council and the AOSpine Research Commission established a competency-based curriculum to improve understanding of what is necessary to produce research and the best methods to achieve this goal. The research curriculum was divided into four main components: (1) research educational plan, (2) performing research, (3) technical and professional support and (4) assessment. RESULTS: The competences, learning outcomes and a syllabus on knowledge in research were developed to enable the participants to understand and perform investigations effectively. The eLearning module was designed to improve the competences to access, evaluate and use scientific information available in the main databases efficiently. Research courses were given as an isolated activity four times in Brazil and Mexico and as precourse activities six times in Brazil, Mexico and Peru. The result was an increased number of articles published and works presented at congresses. CONCLUSIONS: The project of education in research can be effectively disseminated and applied across regions, across students and across specialties.

International and Multicenter Prospective Controlled Study of Dysphagia After Anterior Cervical Spine Surgery.

BACKGROUND: In the context of anterior approach to the cervical spine, dysphagia is a common complication and still without a clear distinction of risk factors. OBJECTIVE: To analyze the risk factors of dysphagia after cervical spine surgery. METHODS: Multicenter prospective study evaluated patients who underwent anterior cervical spine surgery for degenerative pathologies, studying surgical, anesthesia, base disease, and radiological variables (preoperatively, 24 hours, 1 and 3 weeks, and 6 months after surgery), with control group matched. Postoperative dysphagia was assessed by Swallowing Satisfaction Index and Swallowing Questionnaire; besides, based on multiple logistic regression model, a risk factor analysis correlation was applied. RESULTS: In total, 233 cervical patients were evaluated; most common level approached was C5-C6 (71.8%). All showed same decreasing trade for dysphagia incidence-with more cases on cervical group ( P < .05); severe cases were rare. At postoperative day 1, identified risk factors were approach to C3-C4 (4.11, P < .01), loss of preoperative cervical lordosis (2.26, P < .01), intubation attempts ≥2 (3.10, P < .01), and left side approach (1.85, P = .02); at day 7, body mass index ≥30 (2.29, P = .02), C3-C4 (3.42, P < .01), and length of surgery ≥90 minutes (2.97, P = .005); and at day 21, C3-C4 were kept as a risk factor (3.62, P < .01). CONCLUSION: A high incidence level of dysphagia was identified, having a clear decreasing trending (number of cases and severity) through postoperative time points; considering possible risk factors, strongest correlation was the approach at the C3-C4 level-statistically significant at the 24 hours, 7 days, and 21 days assessment.

COVID-19 Impact Among Spine Surgeons in Latin America.

STUDY DESIGN: Cross-sectional study. OBJECTIVE: The aim of this study was to evaluate the impact of the COVID-19 outbreak in spine surgeons in Latin America. METHODS: A questionnaire was sent to Latin American spine surgeons from April 4 to 6, 2020. Surgeon characteristics were recorded. The impact of COVID-19 on economic well-being, work, and mental health were also determined. All variables were compared and analyzed. RESULTS: Two hundred four surgeons answered the complete survey; most of them were male (96.6%), the average age was 47.7 years; 58.8% (n = 120) were orthopedic surgeons and 41.2% (n = 84) were neurosurgeons. The majority of the respondents were from Argentina (59.8%, n = 122), followed by Brazil (17.2%, n = 35), Chile (6.4%, n = 13), and Mexico (5.9%, n = 12). Most of the surgeons reported performing emergency procedures only during the pandemic (76.5%, n = 156). Half used telemedicine or online consultation modalities (54.4%, n = 111). The average concern about the financial situation due to the pandemic was 7.53 in a scale of 1 to 10 (10 being the worst scenario). Twenty-two percent (n = 45) of the surgeons had a score over 10 in the Patient Health Questionnaire (PHQ-9; scores higher than 10 needs referral to confirm depression diagnosis). Young age and neurosurgery as a specialty were associated with higher PHQ-9 scores. CONCLUSIONS: COVID-19 has an impact in the daily working practice and financial situation of spine surgeons in Latin America. The long-term psychological impact should be taken into consideration to avoid a heavier burden for health care providers.

Lumbar Selective Nerve Root Block: Comparative Study Using Two Pharmacological Formulae.

STUDY DESIGN: Retrospective cohort study. OBJECTIVES: The objective of the present study was to compare the effectiveness of 2 different pharmacological formulae in selective nerve root injections. METHODS: We studied a series of 298 patients who received a selective nerve root injection and made a comparative study dividing them into 2 groups according to the drugs used. In group A, we used betamethasone 6 mg and lidocaine, while in group B, triamcinolone 60 mg and bupivacaine were used for the procedure. We evaluated the patients for a period of at least 8 months, assuming the need for surgical therapy as the failure of the procedure. RESULTS: Both groups had 149 patients with similar etiological characteristics. Forty-seven patients (16%) required surgery to relieve pain with a similar distribution between groups (24 from group A and 23 from group B). Time between nerve root injection and surgery was 86.79 (14-360) days on average in group A and 75.76 (2-180) days in group B with no statistical difference (P = .67). Only one complication was documented, an anaphylactic shock in a patient in group B. CONCLUSIONS: Based on these results, we found no difference in the type of steroid or local anesthetic used for selective nerve root injections.

Técnica de "slalom" quirúrgico en estenosis de canal lumbar multinivel. Serie de casos tratados de manera simultánea con descompresión endoscópica y tubular con asistencia microscópica bilateral / Slalom Technique as a treatment in multilevel lumbar spinal stenosis. Series of cases treated simultaneously with endoscopic and tubular decompression with microscopic assistance

Introducción: La laminectomía unilateral para descompresión bilateral por abordaje único ha tomado relevancia en pacientes con estenosis multinivel. Cuando se realiza en más de un nivel por un abordaje único, de manera alterna y de forma cruzada, al abordaje anterior es conocida como técnica de "slalom". Elobjetivode este artículo es presentar una serie de casos tratados con la técnica de "slalom" con asistencia endoscópica y microscópica bilateral, simultánea, en pacientes con estenosis de canal lumbar multinivel.materiales y métodos: Análisis retrospectivo de pacientes tratados de forma simultánea, entre enero de 2017 y enero de 2018, todos operados por el mismo equipo quirúrgico con separadores tubulares, y asistencia endoscópica y micros-cópica simultánea.Resultados: Se incluyó a 4 hombres, con una edad promedio de 73.5 años y patología lumbar multinivel. Se descomprimieron 10 segmentos (2,5 media de niveles por paciente), con un tiempo quirúrgico promedio de 107 minutos. No hubo complicaciones asociadas y los pacientes recibieron el alta hospitalaria el día de la cirugía.Conclusiones:La técnica de "slalom" mínimamente invasiva resulta ser un procedimiento muy eficaz para resolver síntomas de estenosis multinivel asociada a una técnica combinada bilateral con dos equipos quirúrgicos para el tratamiento de este tipo de pacientes. Nivel de Evidencia: IV

Introduction: Unilateral laminectomy for bilateral decompression (ULBD) by single approach has become relevant in patients with multilevel stenosis, when it is performed at more than one level with single approach, alternately and crosswise to the previous approach is known as a slalom technique.The objective of the following work is to present a series of cases treated with the slalom technique with bilateral endoscopic and microscopic assistance, simultaneous in patients with multilevel lumbar canal stenosis. Materials and Methods: Retrospective analysis of patients treated simultaneously between the months of January 2017 to January 2018, all operated by the same surgical team with tubular separators and simultaneous endoscopic and microscopic assistance. Results: Four patients, all male, with an average age of 73.5 years with multilevel lumbar pathology, were included. In total 10 segments were decompressed (2.5 average level for patients), with an average surgery of 107 minutes. No associated complications, with hospital discharge within the day of surgery. Conclusions: The minimally invasive Slalom technique turns out to be a very effective procedure to resolve symptoms of multilevel stenosis associated with a bilateral combined technique with two surgical teams, resulting in a viable option for the treatment of this type of patient. Level of Evidence: IV

Descompresión lumbar en pacientes con enfermedad de Parkinson: serie de casos tratados con cirugía mínimamente invasiva / Lumbar decompression in patients with Parkinson's disease: series of cases treated with minimally invasive surgery

Introducción: La enfermedad de Parkinson afecta principalmente a personas >65 años. El cuadro degenerativo lumbar en el contexto de un canal estrecho sumado a la alteración neuromuscular y la mala calidad ósea, favorece al desequilibrio sagital y coronal. Los pacientes que necesitan cirugía tienen altas tasas de revisión y reoperación con técnicas instrumentadas y no ins-trumentadas. El objetivo de este estudio fue evaluar la técnica quirúrgica de descompresión mínimamente invasiva en pacientes con enfermedad de Parkinson y dolor radicular o claudicación neurogénica en los miembros inferiores. materiales y métodos: Se evaluó a pacientes con diagnóstico de canal lumbar estrecho y enfermedad de Parkinson tratados quirúrgicamente. El procedimiento se indicó por síntomas de canal estrecho o estenosis foraminal de causa degenerativa. Todos fueron tratados con una cirugía descompresiva a través de una hemilaminectomía mínimamente invasiva mediante retracción tubular y asistencia con microscopia. Resultados: De enero de 2015 a diciembre de 2017, se trató a 6 pacientes con enfermedad de Parkinson y canal lumbar estrecho. Se descomprimieron 12 niveles en total, todos estuvieron internados <24 h. No se necesitaron transfusiones, no hubo complicaciones asociadas, el tiempo promedio de cirugía fue de 120 minutos. El seguimiento mínimo fue de 12 meses, los síntomas no reaparecieron. Conclusiones: La elevada tasa de complicaciones en pacientes operados con enfermedad de Parkinson y la disminución de las complicaciones en este estudio sugieren que la cirugía mínimamente invasiva de columna lumbar debería ser una alternativa quirúrgica en estos pacientes. Nivel de Evidencia: IV

Introduction: Parkinson's disease mainly affects patients aged 65 and older. The degenerative condition at the lumbar spine in the context of a narrow canal added to the neuromuscular disorder and poor bone quality favors sagittal and coronal imbalance. Patients who need surgery have high rates of revision and reoperation with instrumented and non-instrumented techniques. The objective of this study was to evaluate the minimally invasive surgical decompression technique in patients with Parkinson's disease and radicular pain or neurogenic claudication in the lower limbs. Materials and Methods: Surgically treated patients with a diagnosis of lumbar spinal stenosis and Parkinson's disease were evaluated. The indication for the procedure was due to symptoms of the lumbar or foraminal stenosis of degenerative cause. All the patients were treated with decompressive surgery through a minimally invasive hemilaminectomy using tubular retraction and assistance with microscopy. Results: From January 2015 to December 2017, 6 patients with Parkinson's disease and lumbar spinal stenosis were treated. A total of 12 segments were decompressed, all patients were hospitalized for less than 24 hours. They did not require a transfusion nor suffered associated complications, with an average surgery time of 120 minutes. All with a minimum follow-up of 12 months and no relapse of the symptoms. Conclusion: The high rate of surgical complications in patients with Parkinson's disease, in contrast to the low rate of complications in the present study, suggests that minimally invasive surgery of the lumbar spine should be a surgical alternative in these patients. Level of Evidence: IV

Trends in scientific publications of Indian spine surgeons over 14 years (2000-2013).

BACKGROUND: The number and quality of scientific publications reflects the standards of scientific research in a country. However, the contribution of Indian spine surgeons toward global publications is unknown. The goal is to study the publications of Indian spine surgeons between 2000 and 2013. MATERIALS AND METHODS: A literature search of the publications by Indian spine surgeons was performed using MEDLINE. The search terms used were India and several spine-related terminologies. The main information of the selected papers including the year of publication, scientific journal, type of pathology studied, Neurosurgical or Orthopedic Department where the study was done, type of study, and the type of article was analyzed. RESULTS: A total of 4459 articles were identified using MEDLINE and after exclusion, 507 articles were analyzed. A growth of 440% in the number of publications was observed in the period between 2009 and 2013, during which 60.15% of the articles were published. Clinical studies (n = 492; 97.04) were the most common types of articles, followed by experimental studies and other types. The Neurosurgery department published the majority of the articles (58.2%). The three most common pathologies studied were spinal tumors (17.35%), surgical technique (15.4%), and spinal infection (15.2%). CONCLUSION: The current study shows that publications in the field of spine surgery have been increasing in the last few years, although it is less. Further efforts such as research training of spine surgeons, inducing collaborations and formulation of multicenter projects and periodically allocating adequate funds are key factors to improve the scientific publications from India.

Hemorragia subaracnoidea posterior a descompresión Lumbar mínimamente invasiva. Presentación de un caso y revisión de la literatura / Subarachnoid hemorrhage after minimally invasive lumbar decompression. Case report and literature review

Introducción: Las lesiones durales son complicaciones frecuentes en la cirugía de columna. La fuga de liquidocefalorraquideo (LCR) puede originar hemorragia en todos los compartimientos del cerebro. La mayoría ocurre en venas ubicadas en región cerebelosa.Material y método: Se presenta un caso de hemorragia subaracnoidea posterior a una descompresión lumbar mínimamente invasiva asociada a desgarro dural. Resultados: Evoluciona en el postoperatorio con síntomas neurológicos de cefaleas y trastornos del sensorio por lo que se decide evaluarlo con estudios por imágenes vasculares cerebrales identificándose sangrado subaracnoideo.Discusión: El sitio más frecuente de hemorragia intracraneal posterior a una cirugía de columna es el cerebelo. El mecanismo de acción de este tipo de sangrados es desconocido y controversial, hay algunos reportes que sugieren que se trataría de un sangrado venoso. El síntoma más característico de este síndrome es la cefalea. Aunque se desconoce la etiología exacta, se postula que la pérdida de volumen de LCR causa una caída en la presión intracraneal, lo que lleva a un agrandamiento de los senos venosos durales que predisponen al paciente a un hematoma subdural espontáneoConclusión: La fuga de LCR, las alteraciones asociadas al edema cerebral en la hipotensión cerebral podría ser llave del mecanismo que desencadena una hemorragia subaracnoidea.

compartments of the brain. Most occur in veins located in the cerebellar region.Material and method: A case of subarachnoid hemorrhage after a minimally invasive lumbar decompression associated with dural tear is presented.Results: It evolves in the postoperative period with neurological symptoms of headaches and sensory disorders, so it is decided to evaluate it with studies by cerebral vascular images identifying subarachnoid bleeding.Discussion: The most frequent site of intracranial hemorrhage after spinal surgery is the cerebellum. The mechanism of action of this type of bleeding is unknown and controversial, there are some reports that suggest that it would be a venous bleeding. The most characteristic symptom of this syndrome is headache. Although the exact etiology is unknown, it is postulated that the loss of CSF volume causes a drop in intracranial pressure, which leads to an enlargement of the dural venous sinuses that predispose the patient to a spontaneous subdural hematomaConclusion: CSF leakage, alterations associated with cerebral edema in cerebral hypotension could be key to the mechanism that triggers a subarachnoid hemorrhage.

Tasa de infección en 212 pacientes consecutivos tratados mediante descompresión tubular mininvasiva de la columna lumbar / Infection rate in 212 consecutive patients treated by minimally invasive lumbar tubular decompression

Introducción: Las infecciones del sitio quirúrgico pueden requerir tratamientos prolongados con antibióticos, una estancia hospitalaria más prolongada y operaciones repetidas. Las incisiones pequeñas y la posibilidad de evitar la disección subperióstica en la cirugía mininvasiva pueden reducir, al mínimo, el riesgo de infecciones posoperatorias. Sin embargo, los estudios publicados sobre infecciones después de procedimientos mininvasivos son escasos. El objetivo de este estudio fue evaluar retrospectivamente una serie de pacientes operados, de manera consecutiva, con una técnica mininvasiva y la incidencia de infección posoperatoria. Materiales y Métodos: Se incluyó a los pacientes sometidos a cirugía lumbar posterior con retractores tubulares y microscopio, en nuestro Servicio, entre enero de 2015 y enero de 2018. Los procedimientos realizados fueron discectomías tubulares, descompresiones para la estenosis de canal y resecciones de quistes sinoviales. La incidencia de infección del sitio quirúrgico se calculó y comparó con el rango de tasas de infección del sitio quirúrgico publicado. Resultados: Se realizaron cirugías no instrumentadas (discectomías, descompresiones) en 212 pacientes. La media de la edad era de 62.4 años y la relación hombre:mujer, de 1,27:1. Solo un paciente sufrió una infección del sitio quirúrgico, diagnosticada el día 9 poscirugía, que fue tratada mediante lavado y limpieza de la herida. Conclusión: La tasa de infección fue del 0,47%. La cirugía mininvasiva puede disminuir notablemente la tasa de infección del sitio quirúrgico y puede ser una herramienta eficaz para reducir, al mínimo, los costos hospitalarios. Nivel de Evidencia: IV

Introduction: Surgical site infections (SSI) can lead to prolonged antibiotic treatments, increased hospital stays, and repeated operations. Small incisions and the possibility of avoiding subperiosteal dissection in minimally invasive surgery can minimize the risk of postoperative infections. However, there is a shortage of literature on infections after mini-invasive procedures. Objective: To evaluate retrospectively a series of patients consecutively operated on with minimally invasive technique and the incidence of postoperative infection. Materials and Methods: All patients undergoing posterior lumbar surgery with tubular retractors and microscope in our department from January 2015 to January 2018 were included. The procedures performed included tubular discectomies, lumbar stenosis decompressions, and synovial cyst resections. The incidence of postoperative SSIs was calculated and compared with the literature range for SSI rates. Results: A total of 212 patients underwent non-instrumented surgeries (discectomies, decompressions). The mean age was 62.4 years with a male:female ratio of 1.27:1. Only one patient had SSI, which was diagnosed on day 9 and treated by reoperation, surgical toilet of the wound, and antibiotic therapy. Conclusion: The infection rate was 0.47%. Minimally invasive surgery can significantly reduce the SSI rate and can be an effective tool in minimizing hospital costs. Level of Evidence: IV

Impacto psicosocial de la pandemia por COVID-19 en cirujanos de columna argentinos / Psychosocial impact of the COVID-19 pandemic on Argentine spinal surgeons

Objetivo: Evaluar el impacto psicosocial de la pandemia por COVID-19 en los cirujanos de columna de Argentina. Material y métodos: Se envió un cuestionario diseñado específicamente a los cirujanos de columna de Argentina entre el 4-6 de abril del 2020. Las preguntas incluyeron variables demográficas, económicas, laborales y la escala de depresión PHQ-9. Las variables fueron comparadas y analizadas y las diferencias estadísticamente significativas remarcadas. Resultados: Respondieron en forma completa la encuesta 122 cirujanos de columna de Argentina, la mayoría hombres (97%), la edad promedio fue de 44 años; la mitad (n: 61) eran traumatólogos y la otra mitad neurocirujanos. La mayoría respondieron estar solo haciendo cirugías de emergencia (84%, n: 102). La preocupación promedio respecto a la situación financiera fue de 7.8 en una escala de 1 al 10. El 20% (n: 24) tenía un score superior a 10 en la escala de PHQ-9. Los cirujanos más jóvenes y los neurocirujanos tenían estadísticamente scores de PHQ-9 más altos. Conclusión: Se evaluó el impacto durante la pandemia por COVID-19 en la situación laboral y financiera de los cirujanos de columna encuestados. El impacto psicológico en el largo plazo debe ser considerado, para evitar secuelas en este grupo de profesionales de la salud.

Objective: The aim of this study is to evaluate the psycho-social impact of the COVID-19 outbreak in spine surgeons in Argentina. Methods: A questionnaire was sent to Argentina spine surgeons from April 4-6th, 2020. Questions regarding demographics, economic, working status and the PHQ-9 score were included. All variables were compared, analyzed and statistically significant differences were recorded. Results: 122 surgeons from Argentina answered the complete survey, most of them were male (97 %), the average age was 44 years; half (n: 61) of them were orthopedic surgeons and half neurosurgeons. Most of the surgeons reported performing emergency procedures only during the pandemic (84 %, n: 102). The average concern about the financial situation due to the pandemic was 7.8 in a scale of 1 to 10. Twenty percent (n: 24) of the surgeons had a score over 10 in the PHQ-9. Young age and neurosurgery as a specialty were statistically related with higher PHQ-9 scores. Conclusions: COVID-19 impact ́s in working practice and financial situation of Argentina ́s spine surgeons that answered this survey was evaluated. The long-term psychological impact should be taken into consideration to avoid a heavier burden for health care providers.

Twelve years of scientific production on Medline by Latin American spine surgeons.

BACKGROUND: Despite the small contribution of LA in the Science Citation Index (SCI), a growing contribution by LA research to international literature has been observed in recent years. STUDY DESIGN: Systematic review. PURPOSE: To evaluate the scientific contribution of Latin American (LA) Spine Surgeons in the last decade. METHODS: A literature search of publications by LA spinal surgeons on topics concerning the spine or spinal cord was performed using an online database; Pubmed.gov. The results were limited to articles published from January 2000 to December 2011. The quality of the publication was evaluated with the journal impact factor (IF), Oxford classification and number of citations. RESULTS: This study comprised 320 articles published in the Medline database by LA spine surgeons from 2000 to 2011. In recent years, there has been an increase in the number of publications by LA spine surgeons. It was observed that 38.4% of LA papers were published in LA journals. 46.6% of the articles were published in journals with an IF lower than 1, and there was no statistically significant difference in the number of articles published in journals with a higher IF during the period. Linear-by-linear association analysis demonstrated an improvement in the level of evidence provided by LA articles published in recent years. CONCLUSIONS: This study showed a growth in the number of publications in last 12 years by LA spinal surgeons. It is necessary to discuss a way to increase quantity and quality of scientific publications, mainly through a better education in research.

Informe sobre la radio-exposición en el personal quirúrgico de Ortopedia y Traumatología: Principios, marco legal y análisis situacional en la Argentina / Report on the radiation exposure in Orthopedic and Traumatology surgical staff. Principles, legal framework, and situational analysis in Argentina

La cirugía ortopédica ha avanzado mucho en estos años y, con ello, el uso de la intensificación de imágenes en el quirófano. El objetivo de este informe es revisar los principios biológicos de la radiación, el marco legal actual y hacer una breve reseña sobre la situación actual en la Argentina.

Orthopedic surgery has significantly advanced in the past years along with image intensifier fluoroscopy in the operating room. The purpose of this report is to review biological principles of radiation, as well as the current legal framework and to outline the present situation in Argentina.

Espondilolistesis traumática lumbosacra. reporte de cuatro casos y revisión de la bibliografía / Traumatic lumbosacral spondylolisthesis. report of four cases and literature review

En 1976, Wiltse y cols. clasificaron a las espondilolistesis en cinco tipos, según su etiología: displásica, ístmica, degenerativa, tumoral y traumática. Esta última es una de las más infrecuentes; hasta la fecha, se han publicado muy pocos casos. Las espondilolistesis traumáticas son lesiones poco frecuentes. Su causa suele estar relacionada con traumas de alta energía y es frecuente su asociación con lesiones de órganos abdominales, craneoencefálicos y tórax. La gran mayoría de estas lesiones son habitualmente de resolución quirúrgica por su alta inestabilidad. Se presentan cuatro pacientes operados en el último tiempo, con un seguimiento mínimo de 4 años, y una revisión actualizada de la literatura.

In 1976 Wiltse et al. described a spondylolisthesis classification in five types according to their etiology: dysplastic, isthmic, degenerative, tumoral and traumatic, the last one being the less common; there are very few reports in the literature. Traumatic spondylolisthesis is a very rare entity with few reports in the literature. It is usually associated with high energy trauma and abdominal, craneoencephalic and thoracic lesions should always be discarded. Most of these lesions should be resolved surgically due to its high mechanical instability. We report four cases with traumatic spondylolisthesis operated on during last years, with a minimum follow-up of 4 years. An update review is presented.

Seudoartrosis atrófica: Efecto de la aplicación de ondas de choque extracorpóreas en un modelo experimental en tibia de conejos / Atrophic pseudoartrosis. Effect of extracorporeal shock waves application in an experimental model in tibia of rabbits

Introducción: Los efectos de las ondas de choque extracorpóreas se han investigado en osteoblastos humanos, focos fracturarios, seudoartrosis y células periósticas. Los mejores resultados del tratamiento de la seudoartrosis con ondas de choque extracorpóreas se han documentado para seudoartrosis hipertróficas. El objetivo de este estudio fue investigar el efecto de la terapia con ondas de choque extracorpóreas sobre un foco de seudoartrosis "atrófica" generado en tibia de conejo. Métodos: Se establecieron tres grupos: A, fracturados sometidos a ondas de choque extracorpóreas; B ("control"), fracturados no sometidos a ondas de choque y C, no fracturados (pierna derecha). Se trataron 37 conejos (cuniculus NV) blancos y esqueléticamente maduros de Nueva Zelanda. Se practicó la cauterización del periostio con electrobisturí bipolar en una extensión de 20 mm, en ambos muñones óseos (proximal y distal). Luego se aplicaron ondas de choque extracorpóreas en una sola sesión. Se realizaron tinciones con hematoxilina-eosina. Se efectuó el análisis biomecánico con un método de carga a "3 puntos". Se estudiaron la carga máxima aplicada y el módulo de elasticidad para cada grupo. Resultados: El estudio histológico permitió registrar signos de consolidación -callo fracturario perióstico y endostal- considerablemente mayores en las tibias de los animales del grupo A (tratado con ondas de choque extracorpóreas) que en las del grupo B "control". Conclusión: En un modelo experimental original de seudoartrosis atrófica generada por electrocauterización en tibia de conejos, se registraron cambios significativos radiográficos e histológicos luego de la intervención del foco mediante ondas de choque extracorpóreas. Nivel de Evidencia: II

Introduction: The effects of extracorporeal shock wave therapy (ESWT) have been investigated in human osteoblasts, fracture foci, nonunion and periosteum cells. The best results of nonunion treatment with ESWT have been documented for hypertrophic type. The objective of this study was to investigate the effects of ESWT in an atrophic nonunion focus generated in a rabbit tibia model. Methods: Three groups were included: A, fractures receiving ESWT; B ("control"), fractures not receiving ESWT, and C, no fractures (right leg). A total of 37 New Zealand white and skeletally mature rabbits (cuniculus NV) were treated. Periosteum was cauterized using bipolar electrocautery at 20 mm in both bone stumps (proximal and distal). Then ESWT was applied in one session. Staining with hematoxylin-eosin was used. A biomechanical analysis with a 3-point loading system was performed. Maximum load and elastic modulus were evaluated in each group. Results: Histological study evidenced signs of union (periosteal and endosteal fracture callus) which were considerably larger in tibias of Group A (treated with ESWT) as compared to the control group (Group B). Conclusion: In an experimental model of atrophic pseudarthrosis caused by electrocautery in tibias of rabbits, significant radiographic and histological changes were observed after focus intervention with the application of ESWT. Level of Evidence: II

Chemoattraction of progenitor cells by remodeling extracellular matrix scaffolds.

The chemotactic properties of a biologic scaffold composed of extracellular matrix (ECM) and subjected to in vivo degradation and remodeling were evaluated in a mouse model of Achilles tendon reconstruction. Following a segmental resection of the Achilles tendon in both C57BL/6 and MRL/MpJ mice, the defect was repaired with either an ECM scaffold composed of urinary bladder matrix (UBM) or resected autologous tendon. The surgically repaired and the contralateral tendons were harvested at 3, 7, and 14 days following surgery from each animal. Chemotaxis of multipotential progenitor cells toward the harvested tissue was quantified using a fluorescent-based cell migration assay. Results showed greater migration of progenitor cells toward tendons repaired with UBM-ECM scaffold compared to both the tendons repaired with autologous tissue and the normal contralateral tendon in both the MRL/MpJ and C57BL/6 mice. The magnitude and temporal pattern of the chemotactic response differed between the two mouse strains.

Asociación entre los defectos del cementado femoral y los valores de la presión arterial media / Association between femoral cementation defects and mean arterial pressure values

Introduccion: Se ha demostrado que la disminución dela presión arterial media (PAM) produce un efectohemostático en el conducto endomedular. En relación con la calidad del cementado en las artroplastias, no se han hallado publicaciones que correlacionen in vivo los valores de PAM y los defectos de cementación. Se diseñó un estudio de corte transversal de correlación con el objetivo de investigar la posible asociación entreestos dos factores. Materiales y métodos: Se seleccionaron 56 pacientes sometidos a artroplastias primarias de cadera, de acuerdo con un muestreo por conveniencia. Los valores de presión arterial media durante el cementado se obtuvieron mediante la revisión de los monitoreos anestésicos intraoperatorios. Se consideraron defectos de cementado las burbujas y radiolucencias presentes en la interfaz hueso-cemento. Se efectuaron cálculos de regresión con el método de Spearman entre ambas variables. Resultados: La cantidad de burbujas encontradas por región femoral no se correlacionó con la PAM, R2 = 0,02 (p > 0,05). Se observó una asociación estadísticamente significativa entre la mayor cantidad de radiolucencias en el manto de cemento y los mayores valores de PAM, R2 = 0,7 (p < 0,05). Conclusiones: Se ha logrado establecer una correlación lineal entre la aparición de defectos del cementado en forma de radiolucencias y los valores de la PAM. En cuanto a los defectos denominados burbujas, no seobservó tal correlación.

Evolucion del reemplazo total de rodilla con componente tibial de polietileno a mediano plazo / Medium-term evolution of total knee replacement with polyethylene tibial component

Introduccion: En los inicios de la cirugía artroplástica protésica de la rodilla el componente tibial era de polietileno en su totalidad; con el advenimiento de las bases tibiales metálicas ese diseño fue dejado a un lado. En la actualidad la indicación electiva de dicho implante es motivo de revisión. El objetivo del presente trabajo fue evaluar los resultados clínico-radiológicos obtenidos mediante el empleo de un diseño protésico de rodilla con base tibial “todo de polietileno” con un seguimiento de entre 3 y 5 años. Materiales y métodos: En el período comprendido entre febrero de 2000 y enero de 2002 se realizaron 78 reemplazos totales de rodilla con prótesis PFC variedad “All Poly”® (J&J, DePuy, Warsaw, IN) en 77 pacientes. Las características demográficas y clínicas de los pacientes eran homogéneas. La edad promedio de los participantes era de 79,4 años; 79 por ciento de ellos eran mujeres. Un evaluador externo analizó los resultados mediante los siguientes sistemas de valoración: Knee Society, cuestionario Oxford y la prueba del Hospital for Special Surgery. Resultados: Se observó una importante mejoría funcional tanto subjetiva como objetiva de los pacientes en la evolución a mediano plazo con los RTR “All Poly” ®. No fue posible documentar signos de desgaste del componente tibial mediante el procedimiento radiográfico. Las complicaciones identificadas en el grupo estudiado no tuvieron vinculación causal con el diseño protésico: una tromboembolia pulmonar, una amputación por pie diabético y una infección tardía. Conclusiones: En el grupo estudiado se han registrado resultados satisfactorios a corto y mediano plazo con losdiseños de polietileno. Por su costo comparativamente menor respecto del correspondiente a las bases tibiales metálicas resulta una indicación razonable en los pacientes de edad avanzada con menor demanda funcional y capital óseo adecuado.