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1.
J Environ Manage ; 193: 512-523, 2017 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-28242113

RESUMO

Evaluating the effectiveness of agricultural land management practices in minimizing environmental impacts using models is challenged by the presence of inherent uncertainties during the model development stage. One issue faced during the model development stage is the uncertainty involved in model parameterization. Using a single optimized set of parameters (one snapshot) to represent baseline conditions of the system limits the applicability and robustness of the model to properly represent future or alternative scenarios. The objective of this study was to develop a framework that facilitates model parameter selection while evaluating uncertainty to assess the impacts of land management practices at the watershed scale. The model framework was applied to the Lake Creek watershed located in southwestern Oklahoma, USA. A two-step probabilistic approach was implemented to parameterize the Agricultural Policy/Environmental eXtender (APEX) model using global uncertainty and sensitivity analysis to estimate the full spectrum of total monthly water yield (WYLD) and total monthly Nitrogen loads (N) in the watershed under different land management practices. Twenty-seven models were found to represent the baseline scenario in which uncertainty of up to 29% and 400% in WYLD and N, respectively, is plausible. Changing the land cover to pasture manifested the highest decrease in N to up to 30% for a full pasture coverage while changing to full winter wheat cover can increase the N up to 11%. The methodology developed in this study was able to quantify the full spectrum of system responses, the uncertainty associated with them, and the most important parameters that drive their variability. Results from this study can be used to develop strategic decisions on the risks and tradeoffs associated with different management alternatives that aim to increase productivity while also minimizing their environmental impacts.


Assuntos
Conservação dos Recursos Naturais , Recursos Hídricos , Agricultura , Hidrologia , Modelos Teóricos
2.
J Environ Qual ; 43(4): 1334-44, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25603081

RESUMO

It is essential to understand sediment and nutrient sources and their spatial and temporal patterns to design effective mitigation strategies. However, long-term data sets to determine sediment and nutrient loadings are scarce and expensive to collect. The goal of this study was to determine seasonal patterns of suspended sediment (SS), total N (TN), and total P (TP) concentrations and loadings for three USGS gauge sites located at the Fort Cobb Reservoir Experimental watershed (FCREW) located in southwestern Oklahoma. Measured instantaneous discharge, SS, TN, and TP concentration data were used to develop lognormal water quality-discharge relationships. The water quality-discharge relationships were used to generate estimated seasonal concentrations and loads based on hourly or 30-min interval discharge. The estimated concentrations and loads were used to determine seasonal patterns for SS, TN, and TP relative to the respective state water quality criteria. Decreasing and increasing monotonic trends were observed for the seasonal time series loads for all three sites, but they were insignificant based on the Spearman test (α = 0.05). The largest loads were estimated during the wet springs and summers. The study SS, TN, and TP target concentrations were exceeded in one season or another. The study results showed that the priority locations to implement the TN and TP conservation practices were the Lake Creek and Willow Creek subwatersheds during the winter and spring seasons. Common practices to mitigate nutrients and suspended sediments include nutrient management, no-till, conversion of cultivated land to pasture, riparian buffers, and animal exclusion.

3.
J Environ Qual ; 43(4): 1280-97, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25603076

RESUMO

Climate variability, changing land use and management, and dynamic policy environments are the main reasons why long-term research is needed to understand and predict possible water quality outcomes to alternative future scenarios. Long-term water quality data sets are needed to address these water issues. Such data sets were acquired by the USDA-ARS in three watersheds in Oklahoma: the Southern Great Plains Research Watershed (SGPRW), the Little Washita River Experimental Watershed (LWREW), and the Fort Cobb Reservoir Experimental Watershed (FCREW). We provide: (i) a description of these water quality data sets, (ii) the sample collection and processing procedures used and an assessment of the data quality, (iii) summary analyses of the variability in each data set, and (iv) details about how to access these data sets. Water quality data collection in the SGPRW began in the 1960s and continued through 1978, while that in the LWREW covered the 1960s to 1990 period. Data collection began in the FCREW in 2004 and continues through the present. The data were collected from streams, unit source watersheds, groundwater wells, and reservoirs. The water quality data described for a given site are generally complete for a given period of record; however, not all sites were monitored continuously and were not necessarily analyzed for the same water quality parameters. These data sets are expected to improve modeling and assessments of conservation practices in relation to climate variability, land use changes, and other environmental factors and may be useful in developing strategies to mitigate these environmental impacts.

4.
J Environ Qual ; 43(4): 1239-49, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25603072

RESUMO

Hydrologic, watershed, water resources, and climate-related research conducted by the USDA-ARS Grazinglands Research Laboratory (GRL) are rooted in events dating back to the 1930s. In 1960, the 2927-km Southern Great Plains Research Watershed (SGPRW) was established to study the effectiveness of USDA flood control and soil erosion prevention programs. The size of the SGPRW was scaled back in 1978, leaving only the 610-km Little Washita River Experimental Watershed (LWREW) to be used as an outdoor hydrologic research laboratory. Since 1978, the number of measurement sites and types of instruments used to collect meteorologic and soil climate data have changed on the LWREW. Moreover, a second research watershed, the 786-km Fort Cobb Reservoir Experimental Watershed (FCREW), was added in 2004 to the GRL's outdoor research laboratories to further study the effects of agricultural conservation practices on selected environmental endpoints. We describe the SGPREW, FCREW, and LWREW and the meteorologic measurement network (historic and present) deployed on them, provide descriptions of measurements, including information on accuracy and calibration, quality assurance measures (where known), and data archiving of the present network, give examples of data products and applications, and provide information for the public and research communities regarding access and availability of both the historic and recent data from these watersheds.

6.
Rev Esp Anestesiol Reanim (Engl Ed) ; 69(8): 502-505, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-36088271

RESUMO

Effective management and control of peri- and postoperative pain in hip surgery is essential in order to minimize the use of opioids and their adverse effects. Effective regional analgesia for hip pain is made particularly challenging by the complex innervation of the hip joint. Standard regional techniques can be associated with complications, including incomplete anesthesia, hypotension, or lower limb weakness. We present the case of a 5-year-old girl with a history of infantile cerebral palsy who underwent bilateral varus derotation osteotomy and adductor tenotomy due to paralytic dislocation. She received bilateral PENG block and femoral cutaneous nerve block-a simple technique that covers all the nerves involved in the sensory innervation of the joint capsule without the need for multiple injections.


Assuntos
Analgesia , Bloqueio Nervoso , Analgésicos Opioides , Criança , Pré-Escolar , Feminino , Humanos , Bloqueio Nervoso/métodos , Manejo da Dor/métodos , Dor Pós-Operatória/tratamento farmacológico , Dor Pós-Operatória/prevenção & controle
7.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-34538664

RESUMO

Effective management and control of peri- and postoperative pain in hip surgery is essential in order to minimize the use of opioids and their adverse effects. Effective regional analgesia for hip pain is made particularly challenging by the complex innervation of the hip joint. Standard regional techniques can be associated with complications, including incomplete anesthesia, hypotension, or lower limb weakness. We present the case of a 5-year-old girl with a history of infantile cerebral palsy who underwent bilateral varus derotation osteotomy and adductor tenotomy due to paralytic dislocation. She received bilateral PENG block and femoral cutaneous nerve block - a simple technique that covers all the nerves involved in the sensory innervation of the joint capsule without the need for multiple injections.

8.
J Appl Microbiol ; 105(4): 1017-25, 2008 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18422952

RESUMO

AIMS: The species identification and antimicrobial resistance profiles were determined for enterococci isolated from Southern California surface and ocean waters. METHODS AND RESULTS: Species identification was determined for 1413 presumptive Enterococcus isolates from urban runoff, bay, ocean and sewage water samples. The most frequently isolated species were Enterococcus faecalis, Enterococcus faecium, Enterococcus hirae, Enterococcus casseliflavus and Enterococcus mundtii. All five of these species were isolated from ocean and bay water with a frequency ranging from 7% to 36%. Enterococcus casseliflavus was the most frequently isolated species in urban runoff making up 36-65% of isolates while E. faecium was the most frequently isolated species in sewage making up 53-78% of isolates. The similar distribution of species in urban runoff and receiving water suggests that urban runoff may be the source of Enterococcus. No vancomycin or high level gentamycin resistance was detected in E. faecalis and E. faecium isolates. CONCLUSIONS: Enterococcus faecalis, E. faecium, E. casseliflavus and E. mundtii are the most commonly isolated Enterococcus species from urban runoff and receiving waters in Southern California. SIGNIFICANCE AND IMPACT OF THE STUDY: Determination of the Enterococcus species isolated from receiving waters and potential pollution sources may assist in determining the sources of pollution.


Assuntos
Farmacorresistência Bacteriana Múltipla , Enterococcus/isolamento & purificação , Microbiologia da Água , Cidades , Resistência Microbiana a Medicamentos , Enterococcus/fisiologia , Enterococcus faecalis/isolamento & purificação , Enterococcus faecalis/fisiologia , Enterococcus faecium/isolamento & purificação , Enterococcus faecium/fisiologia , Monitoramento Ambiental/métodos , Testes de Sensibilidade Microbiana , Chuva , Esgotos/microbiologia
9.
Shock ; 8(6): 427-31, 1997 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-9421856

RESUMO

When oxygen delivery (DO2) critically decreases, oxygen consumption (VO2) becomes supply dependent. We examined whether end-tidal PCO2 (PetCO2) would identify supply dependency during shock. Five dogs (Group I) underwent progressive hemorrhage to decrease DO2 until they could no longer maintain a stable blood pressure. Five additional animals (Group II) were bled until VO2 decreased to 70% of baseline, followed by resuscitation. The PetCO2 versus time inflection point was compared with the DO2 at onset of supply dependency (DO2crit). DO2crit for Groups I and II were 6.9 +/- .4 and 8.1 +/- 1.3, respectively (p = NS), and not statistically different from the DO2 values at which PetCO2 decreased (6.6 +/- .7 and 6.3 +/- .7 mL/kg per min, respectively). AT constant minute volume, PetCO2 effectively indicated the onset of supply dependency and rapidly increased during resuscitation, paralleling the changes in VO2 in this model of hemorrhagic shock.


Assuntos
Dióxido de Carbono/sangue , Consumo de Oxigênio/fisiologia , Ressuscitação , Choque Hemorrágico/sangue , Choque Hemorrágico/fisiopatologia , Animais , Transfusão de Sangue , Cães , Hemodinâmica , Ácido Láctico/sangue , Oxigênio/administração & dosagem , Pressão Parcial , Análise de Regressão , Respiração/fisiologia , Volume de Ventilação Pulmonar
10.
Chest ; 113(4): 1078-83, 1998 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-9554650

RESUMO

STUDY OBJECTIVES: To validate capnometric recirculating gas tonometry (CRGT) for continuously monitoring gut intramucosal PCO2 (PiCO2) in a septic shock model, and to compare gastric vs esophageal PCO2 vs intramucosal-arterial PCO2 gradients. INTERVENTIONS: CRTG catheters were placed in the stomach and esophagus of six anesthetized dogs. A saline solution filled balloon tonometry (ST) catheter was also placed in the stomach. After equilibration, 3 mg/kg Escherichia coli lipopolysaccharide (LPS) was administered IV. PiCO2 measurements were made at 0, 45, and 90 min post-LPS by ST and continuously by CRGT. RESULTS: Baseline PiCO2 was 41.5+/-1.9 (+/-SE) in the stomach by CRGT, 38.0+/-1.0 by ST, and 43.0+/-4.4 mm Hg in the esophagus (p=not significant). Gastric PiCO2 by CRGT increased to 47.0+/-2.4 mm Hg by 25 min post-LPS (p<0.05), whereas gastric (ST) and esophageal PiCO2 increased significantly by 45 min post-LPS. Good agreement was observed between gastric CRGT and ST measurements (mean bias, 1.3 mm Hg). The PiCO2-PaCO2 gradient increased post-LPS, but was significant only for gastric CRGT measurements 90 min post-LPS infusion. CONCLUSION: CRGT provided continuous gastric PiCO2 measurements that were in close agreement with ST but detected changes earlier than the conventional technique. Continuous esophageal PiCO2 represents a valid alternative for assessing gastric PiCO2.


Assuntos
Endotoxemia/metabolismo , Esôfago/metabolismo , Mucosa Gástrica/metabolismo , Choque Séptico/metabolismo , Animais , Dióxido de Carbono/análise , Modelos Animais de Doenças , Cães , Endotoxemia/fisiopatologia , Hemodinâmica , Concentração de Íons de Hidrogênio , Monitorização Fisiológica/métodos , Mucosa , Oxigênio/análise , Choque Séptico/fisiopatologia
11.
J Appl Physiol (1985) ; 87(3): 1102-6, 1999 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-10484583

RESUMO

The effects of hypocapnia [arterial PCO(2) (Pa(CO(2))) 15 Torr] on splanchnic hemodynamics and gut mucosal-arterial P(CO(2)) were studied in seven anesthetized ventilated dogs. Ileal mucosal and serosal blood flow were estimated by using laser Doppler flowmetry, mucosal PCO(2) was measured continuously by using capnometric recirculating gas tonometry, and serosal surface PO(2) was assessed by using a polarographic electrode. Hypocapnia was induced by removal of dead space and was maintained for 45 min, followed by 45 min of eucapnia. Mean Pa(CO(2)) at baseline was 38.1 +/- 1.1 (SE) Torr and decreased to 13.8 +/- 1.3 Torr after removal of dead space. Cardiac output and portal blood flow decreased significantly with hypocapnia. Similarly, mucosal and serosal blood flow decreased by 15 +/- 4 and by 34 +/- 7%, respectively. Also, an increase in the mucosal-arterial PCO(2) gradient of 10.7 Torr and a reduction in serosal PO(2) of 30 Torr were observed with hypocapnia (P < 0.01 for both). Hypocapnia caused ileal mucosal and serosal hypoperfusion, with redistribution of flow favoring the mucosa, accompanied by increased PCO(2) gradient and diminished serosal PO(2).


Assuntos
Dióxido de Carbono/metabolismo , Hipocapnia/metabolismo , Mucosa Intestinal/metabolismo , Circulação Esplâncnica/fisiologia , Alcalose Respiratória/sangue , Alcalose Respiratória/fisiopatologia , Animais , Artérias/metabolismo , Gasometria , Pressão Sanguínea/fisiologia , Dióxido de Carbono/sangue , Cães , Frequência Cardíaca/fisiologia , Oxigênio/sangue , Espaço Morto Respiratório/fisiologia
12.
J Appl Physiol (1985) ; 91(2): 596-602, 2001 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-11457770

RESUMO

The effects of fenoldopam, a dopamine-1 (DA-1) receptor agonist, were studied in two groups of anesthetized dogs before and after induction of splanchnic ischemia by way of hemorrhage. During the first portion of the experiment, both groups received fenoldopam (1.5 microg x kg(-1) x min(-1)) for 45 min followed by a 45-min washout. During the second portion, hemorrhage (10 ml/kg) was induced, followed by no intervention in group I (controls) and restarting of the fenoldopam infusion in group II. Prehemorrhage, fenoldopam increased composite portal blood flow by 33% (P < 0.01). After hemorrhage-induced splanchnic ischemia, fenoldopam restored portal vein blood flow to near baseline, maintained the splanchnic fraction of cardiac output, and attenuated the rise in gut mucosal PCO(2). DA-1 receptor stimulation increased portal blood flow and redistributed blood flow away from the serosal layer in favor of the mucosa during basal conditions and after hemorrhage, suggesting a more concentrated distribution of splanchnic DA-1 receptors within the mucosal layer vasculature. Fenoldopam maintained splanchnic blood flow during hypoperfusion and attenuated the splanchnic vasoconstrictive response to hemorrhage.


Assuntos
Fenoldopam/farmacologia , Hemodinâmica/fisiologia , Mucosa Intestinal/fisiologia , Isquemia/fisiopatologia , Sistema Porta/fisiologia , Receptores de Dopamina D1/fisiologia , Circulação Esplâncnica/fisiologia , Vasoconstrição/fisiologia , Animais , Pressão Sanguínea , Débito Cardíaco , Cães , Agonistas de Dopamina/farmacologia , Frequência Cardíaca , Hemodinâmica/efeitos dos fármacos , Hemorragia , Mucosa Intestinal/irrigação sanguínea , Intestinos/irrigação sanguínea , Lactatos/sangue , Fígado/irrigação sanguínea , Sistema Porta/efeitos dos fármacos , Receptores de Dopamina D1/efeitos dos fármacos , Fluxo Sanguíneo Regional/efeitos dos fármacos , Circulação Esplâncnica/efeitos dos fármacos , Resistência Vascular , Vasoconstrição/efeitos dos fármacos
13.
J Crit Care ; 13(2): 49-54, 1998 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-9627270

RESUMO

PURPOSE: Gastric intramucosal PCO2 (PiCO2) is a marker of splanchnic dysoxia and hypoperfusion that is increasingly used in intensive care medicine. We assessed two methods, saline-balloon tonometry versus continuous capnometric recirculating gas tonometry (CRGT), for detecting changes in PiCO2 in animals subjected to various degrees of hemorrhage and examined whether changes in PiCO2 would correlate with the degree of hemorrhage as assessed by blood loss volume. MATERIALS AND METHODS: Following a baseline equilibration period, 20 anesthetized dogs were subjected to bleeding of 0, 23, 35, 41, or 47 mL/kg. After 30 minutes, the shed blood was reinfused and the experiments continued for an additional 120 minutes. RESULTS: Aggregate baseline PiCO2 was 43 mm Hg by both methods. PiCO2 did not change significantly over time in the control animals by either method. PiCO2 by CRGT rose significantly in each of the other groups at the end of the hemorrhage period and after resuscitation. Similar trends were observed in PiCO2 measured by saline tonometry but were significant only with the most severe hemorrhage. Strong correlation was observed between the degree of hemorrhage and change in PiCO2 by both methods. CONCLUSION: PiCO2 serves as a quantitative indicator of the severity of hypovolemic perfusion failure associated with hemorrhage. Compared with standard saline tonometry, CRGT may be a more sensitive method of monitoring the severity of hemorrhage.


Assuntos
Volume Sanguíneo/fisiologia , Dióxido de Carbono/sangue , Mucosa Gástrica/irrigação sanguínea , Choque Hemorrágico/fisiopatologia , Animais , Gasometria/instrumentação , Cães , Desenho de Equipamento , Hipóxia/fisiopatologia , Isquemia/fisiopatologia , Sensibilidade e Especificidade , Circulação Esplâncnica/fisiologia
14.
J Trace Elem Med Biol ; 14(2): 81-3, 2000 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-10941717

RESUMO

We investigated the effect of lithium chloride administration (Sigma): 1 mmol/kg b.w. i.p./day for 35 days on the testes and sperm of viscacha (Lagostomus maximus maximus), a nocturnal rodent found only in the pampas of Argentina. The histological study showed that hypospermatogenesis and the sperm number per mL decreased markedly in comparison with the controls (treatment group: 315 x 10(6) +/- 77 x 10(6); control group: 693 x 10(6) +/- 39 x 10(6), Means +/- SEM, Student's t-test: p < 0.05). The sperm motility and viability were also affected. Under the same treatment, the testicular tissue and the sperm of rats were not damaged. Moreover, lithium induced these changes when the plasm levels were within the therapeutic range in humans. Our results provide evidence for the claim that viscacha testes and sperm react very sensitively to low doses of lithium, whereas these concentrations do not produce damage in rats.


Assuntos
Lítio/farmacologia , Espermatozoides/efeitos dos fármacos , Testículo/efeitos dos fármacos , Animais , Masculino , Ratos , Ratos Wistar , Roedores , Motilidade dos Espermatozoides/efeitos dos fármacos , Espermatozoides/metabolismo , Testículo/metabolismo , Testículo/patologia
15.
J Ethnopharmacol ; 88(2-3): 195-8, 2003 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-12963142

RESUMO

The effect of Dehydroleucodine (DhL) on gastric acid secretion in rats was investigated at a dose of 40 mg/kg, while its anti-inflammatory effect was investigated in two experimental models: arthritis induced by Freund's adjuvant carrageenan- and cotton pellet-induced granuloma. DhL did not inhibit gastric acid secretion, suggesting that its anti-ulcerogenic effect can be attributed to its action on the mucosa defense factors. On the other hand, DhL inhibited both chronic and acute adjuvant carrageenan-induced inflammation phases, being most effective in the chronic phase. In the granuloma test, DhL also inhibited inflammation. It is suggested that the anti-inflammatory activity of DhL may be attributed to interference with multiple targets on the level of transcription factors, such as NF-kappaB, and cytokines.


Assuntos
Anti-Inflamatórios não Esteroides/farmacologia , Artemisia/química , Ácido Gástrico/metabolismo , Lactonas/farmacologia , Sesquiterpenos/farmacologia , Animais , Anti-Inflamatórios não Esteroides/isolamento & purificação , Modelos Animais de Doenças , Feminino , Inflamação/induzido quimicamente , Inflamação/tratamento farmacológico , Lactonas/isolamento & purificação , Masculino , Componentes Aéreos da Planta/química , Extratos Vegetais/farmacologia , Ratos , Ratos Wistar , Sesquiterpenos/isolamento & purificação
16.
Ginecol Obstet Mex ; 65: 119-22, 1997 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-9280734

RESUMO

A retrospective study of 182 cases of invasive squamous cell carcinoma of the uterine cervix and 133 cases cases of in situ carcinoma, based on histological classification studies and their relation with mean age, during 1985-1994, is reported in a second level Hospital in Rio Blanco, Veracruz, Mexico. The mean age of invasive cervix carcinoma is 50.2 years and the mean age is not the same in the different clinical stages, stage I 45.1 years; stage II 48.6 years; stage III 54.9 years and stage IV 57.4 years. This finding maybe has clinical importance. The mean age of in situ carcinoma is 43.9 years, late when compare with other series in the literature. Plan some considerations about mass screening cervical cancer program in Mexico.


Assuntos
Carcinoma in Situ/epidemiologia , Carcinoma de Células Escamosas/epidemiologia , Neoplasias do Colo do Útero/epidemiologia , Neoplasias Uterinas/epidemiologia , Adulto , Fatores Etários , Idoso , Feminino , Humanos , México/epidemiologia , Pessoa de Meia-Idade , Estudos Retrospectivos
17.
Ginecol Obstet Mex ; 67: 509-11, 1999 Nov.
Artigo em Espanhol | MEDLINE | ID: mdl-10630054

RESUMO

Sixteen cases of granulomatous mastitis were seen in the Breast Clinic of the Rio Blanco Regional Hospital in Veracruz, México. The mean age was 41.7 years (range 22-62), mean previous pregnancies was 5. Lactancy in last 6 months was registered in 50% of the cases, but no cases of puerperal mastitis were seen. Seventy five percent of the patients presented with a breast mass (mean 6 cm), suspicious of cancer in 62.5%. In 2 of 16 cases (12.5) there was an associated breast carcinoma, and in one case tuberculosis was the etiology. Surgical treatment consisted in wide local excision in 100% and mastectomy in 2 cases. Steroids were not used. Recurrent disease was seen in 2 cases at a mean follow-up of 20 months. Awareness of this rare entity is important for the surgeon and the pathologist because the definitive diagnosis is made microscopically, through evaluation of a wide breast tissue sample.


Assuntos
Neoplasias da Mama/diagnóstico , Granuloma/diagnóstico , Mastite/diagnóstico , Adulto , Neoplasias da Mama/patologia , Neoplasias da Mama/cirurgia , Diagnóstico Diferencial , Feminino , Granuloma/patologia , Granuloma/cirurgia , Humanos , Mastite/patologia , Mastite/cirurgia , Pessoa de Meia-Idade , Estudos Retrospectivos
18.
Transplant Proc ; 44(10): 2940-4, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23195002

RESUMO

BACKGROUND: This article aims to describe an original technique to correct refluxing native ureters observed during a prerenal transplantation study. The correction is performed by intravesical ligation of the native refluxing ureters at the same time as renal transplantation without simultaneous nephrectomy. METHODS: Between January 2004 and December 2010 we performed intravesical ligation of a refluxing ureter simultaneous with a transplantation procedure without a concomittant native nephrectomy in 12 of 345 subjects (3.47%). The 8 bilateral and 4 unilateral ligations were performed on 11 cadaveric and 1 living-related nonidentical donor transplantations. The implantation of the kidney donor ureter was performed anatomically in the bladder trigone through a transvesical ureteroneocystostomy with a transmural, submucosal antireflux tunnel. RESULTS: Early and late postoperative recovery was satisfactory in all patients. There was no documented kidney area pain, proven urinary tract infection, morbidity or mortality attributed to the procedure. CONCLUSIONS: Intravesical ligation is a practical technique to manage vesicoureteral reflux into the native ureters simultaneously with the ureteral implantation of the kidney donor in a single surgical renal transplant procedure without native kidney nephrectomy.


Assuntos
Transplante de Rim , Insuficiência Renal Crônica/cirurgia , Ureter/transplante , Refluxo Vesicoureteral/cirurgia , Adolescente , Adulto , Criança , Cistostomia , Sobrevivência de Enxerto , Humanos , Transplante de Rim/efeitos adversos , Ligadura , Doadores Vivos , Masculino , Insuficiência Renal Crônica/complicações , Fatores de Tempo , Resultado do Tratamento , Ureterostomia , Refluxo Vesicoureteral/complicações , Adulto Jovem
19.
Scanning ; 34(6): 410-7, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22589011

RESUMO

Kaupp and Naimi-Jamal (2010) claimed that the analysis of published loading curves reveals the exponent 3/2 to the depth for nanoindentations with sharp pyramidal or conical tips. To demonstrate this, they plotted the load vs. the penetration depth to the power 3/2. We show, through examples, the authors' assertion is not credible because the methodology used is misleading and it cannot be asserted that the exponent 3/2 has a universal validity that applies to all kinds of materials.

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