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1.
Reg Anesth Pain Med ; 38(2): 106-11, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23222363

RESUMO

BACKGROUND AND OBJECTIVES: Local infiltration analgesia (LIA) reduces pain after total knee arthroplasty without the motor blockade associated with epidural analgesia or femoral nerve block. However, the duration and efficacy of LIA are not sufficient. A saphenous nerve block, in addition to single-dose LIA, may improve analgesia without interfering with early mobilization. METHODS: Forty patients were included in this double-blind randomized controlled trial. All patients received spinal anesthesia for surgery and single-dose LIA during the operation. An ultrasound-guided saphenous nerve catheter was placed postoperatively in the adductor canal at midthigh level. Patients were randomized into 2 groups to receive 15-mL boluses of either ropivacaine 7.5 mg/mL or saline twice daily for 2 postoperative days. RESULTS: Worst pain scores during movement on the day of surgery were significantly lower in the ropivacaine group (median [range] visual analog scale, 3 [0-7] vs 5.5 [0-10]; P < 0.050), as well as pain at rest (visual analog scale, 2 [0-8] vs 4 [0-8]; P = 0.032). Breakthrough pain occurred later in the ropivacaine group (10.5 [range, 0.5-48] hours vs 3.4 [range, 0.5-24] hours; P = 0.011). All patients in the ropivacaine group were able to ambulate on the day of surgery versus 13 patients in the control group (P = 0.004). Fewer patients had sleep disturbance on the first postoperative night in the ropivacaine group (P = 0.038). We found no differences in morphine consumption. CONCLUSIONS: The combination of a saphenous nerve block with single-dose LIA offered better pain relief on the day of surgery than LIA alone.


Assuntos
Amidas/administração & dosagem , Anestésicos Locais/administração & dosagem , Artroplastia do Joelho/efeitos adversos , Extremidade Inferior/inervação , Bloqueio Nervoso/métodos , Dor Pós-Operatória/prevenção & controle , Adulto , Idoso , Amidas/efeitos adversos , Analgésicos Opioides/uso terapêutico , Anestésicos Locais/efeitos adversos , Dor Irruptiva/etiologia , Dor Irruptiva/prevenção & controle , Distribuição de Qui-Quadrado , Dinamarca , Esquema de Medicação , Feminino , Humanos , Injeções , Masculino , Pessoa de Meia-Idade , Bloqueio Nervoso/efeitos adversos , Medição da Dor , Dor Pós-Operatória/diagnóstico , Dor Pós-Operatória/etiologia , Recuperação de Função Fisiológica , Ropivacaina , Índice de Gravidade de Doença , Fatores de Tempo , Resultado do Tratamento , Ultrassonografia de Intervenção
2.
Reg Anesth Pain Med ; 38(6): 526-32, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24121608

RESUMO

BACKGROUND AND OBJECTIVES: Femoral nerve block (FNB), a commonly used postoperative pain treatment after total knee arthroplasty (TKA), reduces quadriceps muscle strength essential for mobilization. In contrast, adductor canal block (ACB) is predominately a sensory nerve block. We hypothesized that ACB preserves quadriceps muscle strength as compared with FNB (primary end point) in patients after TKA. Secondary end points were effects on morphine consumption, pain, adductor muscle strength, morphine-related complications, and mobilization ability. METHODS: We performed a double-blind, randomized, controlled study of patients scheduled for TKA with spinal anesthesia. The patients were randomized to receive either a continuous ACB or an FNB via a catheter (30-mL 0.5% ropivacaine given initially, followed by a continuous infusion of 0.2% ropivacaine, 8 mL/h for 24 hours). Muscle strength was assessed with a handheld dynamometer, and we used the percentile change from baseline for comparisons. The trial was registered at clinicaltrials.gov (Identifier: NCT01470391). RESULTS: We enrolled 54 patients, of which 48 were analyzed. Quadriceps strength as a percentage of baseline was significantly higher in the ACB group compared with the FNB group: (median [range]) 52% [31-71] versus 18% [4-48], (95% confidence interval, 8-41; P = 0.004). There was no difference between the groups regarding morphine consumption (P = 0.94), pain at rest (P = 0.21), pain during flexion of the knee (P = 0.16), or adductor muscle strength (P = 0.39); neither was there a difference in morphine-related adverse effects or mobilization ability (P > 0.05). CONCLUSIONS: Adductor canal block preserved quadriceps muscle strength better than FNB, without a significant difference in postoperative pain.


Assuntos
Amidas/administração & dosagem , Anestésicos Locais/administração & dosagem , Artroplastia do Joelho , Nervo Femoral , Bloqueio Nervoso/métodos , Dor Pós-Operatória/prevenção & controle , Músculo Quadríceps/inervação , Idoso , Analgésicos Opioides/uso terapêutico , Raquianestesia , Artroplastia do Joelho/efeitos adversos , Dinamarca , Método Duplo-Cego , Feminino , Humanos , Infusões Parenterais , Masculino , Pessoa de Meia-Idade , Morfina/uso terapêutico , Força Muscular , Debilidade Muscular/etiologia , Debilidade Muscular/fisiopatologia , Bloqueio Nervoso/efeitos adversos , Dor Pós-Operatória/diagnóstico , Dor Pós-Operatória/etiologia , Estudos Prospectivos , Recuperação de Função Fisiológica , Ropivacaina , Fatores de Tempo , Resultado do Tratamento
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