Detalhe da pesquisa
1.
Comparative pharmacokinetic analysis of levonorgestrel-releasing intrauterine systems and levonorgestrel-containing contraceptives with oral or subdermal administration route.
Eur J Contracept Reprod Health Care
; 25(6): 417-426, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33006493
2.
Topical administration of regorafenib eye drops: phase I dose-escalation study in healthy volunteers.
Br J Clin Pharmacol
; 84(5): 865-875, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29315699
3.
CYP3A4-mediated effects of rifampicin on the pharmacokinetics of vilaprisan and its UGT1A1-mediated effects on bilirubin glucuronidation in humans.
Br J Clin Pharmacol
; 84(12): 2857-2866, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30171692
4.
Pharmacokinetic interaction between the CYP3A4 inhibitor ketoconazole and the hormone drospirenone in combination with ethinylestradiol or estradiol.
Br J Clin Pharmacol
; 80(6): 1399-410, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26271371
5.
Implications of different application sites on the bioavailability of a transdermal contraceptive patch containing ethinyl estradiol and gestodene: an open-label, randomized, crossover study.
Int J Clin Pharmacol Ther
; 52(10): 856-66, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25138681
6.
Systemic exposure to aflibercept after intravitreal injection in premature neonates with retinopathy of prematurity: results from the FIREFLEYE randomized phase 3 study.
Eye (Lond)
; 38(8): 1444-1453, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38200320
7.
Clinical Pharmacokinetics and Pharmacodynamics of the Selective Progesterone Receptor Modulator Vilaprisan: A Comprehensive Overview.
Clin Pharmacokinet
; 61(1): 1-16, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34569009
8.
The Effects of Weak and Strong CYP3A Induction by Rifampicin on the Pharmacokinetics of Five Progestins and Ethinylestradiol Compared to Midazolam.
Clin Pharmacol Ther
; 108(4): 798-807, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32275771
9.
Absence of Drug-Drug Interaction of Anastrozole on Levonorgestrel Delivered Simultaneously by an Intravaginal Ring: Results of a Phase 2 Trial.
J Clin Pharmacol
; 59(7): 1022-1028, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30791125
10.
Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women.
Reprod Sci
; 26(4): 523-531, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29806538
11.
Systemic pharmacokinetic/pharmacodynamic analysis of intravitreal aflibercept injection in patients with retinal diseases.
BMJ Open Ophthalmol
; 4(1): e000185, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30997397
12.
Correction: Systemic exposure to aflibercept after intravitreal injection in premature neonates with retinopathy of prematurity: results from the FIREFLEYE randomized phase 3 study.
Eye (Lond)
; 38(8): 1599-1600, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38332376
13.
Determination of rat serum esterase activities by an HPLC method using S-acetylthiocholine iodide and p-nitrophenyl acetate.
Anal Biochem
; 381(1): 113-22, 2008 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18602882
14.
Absence of Effect of Intravaginal Miconazole, Clindamycin, Nonoxynol-9, and Tampons on the Pharmacokinetics of an Anastrozole/Levonorgestrel Intravaginal Ring.
J Clin Pharmacol
; 58(1): 97-106, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28783867
15.
In Vivo Formation of Ethinylestradiol After Intramuscular Administration of Norethisterone Enantate.
J Clin Pharmacol
; 58(6): 781-789, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29522253
16.
The Effect of Drug Content Reduction on the In Vitro and In Vivo Properties of Levonorgestrel-Releasing Intravaginal Rings.
J Pharm Sci
; 107(4): 1020-1027, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29175414
17.
Characterization of the Pharmacokinetics of Vilaprisan: Bioavailability, Excretion, Biotransformation, and Drug-Drug Interaction Potential.
Clin Pharmacokinet
; 57(8): 1001-1015, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29330782
18.
Establishing a Multidisciplinary Framework to Study Drug-Drug Interactions of Hormonal Contraceptives: An Invitation to Collaborate.
CPT Pharmacometrics Syst Pharmacol
; 7(11): 706-708, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30260082
19.
FDA Public Meeting Report on "Drug Interactions With Hormonal Contraceptives: Public Health and Drug Development Implications".
J Clin Pharmacol
; 58(12): 1655-1665, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30144093
20.
Metabolism in the Gastrointestinal Tract: Relevance for Drug Development.
Drug Res (Stuttg)
; 71(S 01): S8-S10, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34788877