Detalhe da pesquisa
1.
Differential recognition of HIV-stimulated IL-1ß and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages.
PLoS Pathog
; 17(4): e1009417, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33861800
2.
2,4-Diamino-8-quinazoline carboxamides as novel, potent inhibitors of the NAD hydrolyzing enzyme CD38: Exploration of the 2-position structure-activity relationships.
Bioorg Med Chem
; 26(8): 2107-2150, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29576271
3.
Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 ion channel blockers. Part 2.
Bioorg Med Chem Lett
; 20(23): 6989-92, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20974533
4.
N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1.
Bioorg Med Chem Lett
; 20(23): 6983-8, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20971642
5.
Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors.
ACS Med Chem Lett
; 10(11): 1518-1523, 2019 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31749904
6.
Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP).
Bioorg Med Chem Lett
; 18(15): 4360-3, 2008 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18606544
7.
Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility.
PLoS One
; 10(8): e0134927, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26287487
8.
Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38.
J Med Chem
; 58(17): 7021-56, 2015 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26267483
9.
Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors.
J Med Chem
; 58(8): 3548-71, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25828863
10.
Structure-based design of potent retinoid X receptor alpha agonists.
J Med Chem
; 47(8): 2010-29, 2004 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-15056000
11.
2-Cyano-4-fluoro-1-thiovalylpyrrolidine analogues as potent inhibitors of DPP-IV.
Bioorg Med Chem Lett
; 15(23): 5257-61, 2005 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16168640
12.
Novel selective small molecule agonists for peroxisome proliferator-activated receptor delta (PPARdelta)--synthesis and biological activity.
Bioorg Med Chem Lett
; 13(9): 1517-21, 2003 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12699745