Detalhe da pesquisa
1.
Smooth muscle cell CYB5R3 preserves cardiac and vascular function under chronic hypoxic stress.
J Mol Cell Cardiol
; 162: 72-80, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34536439
2.
Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction.
Circulation
; 144(8): 615-637, 2021 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157861
3.
Xanthine Oxidase Drives Hemolysis and Vascular Malfunction in Sickle Cell Disease.
Arterioscler Thromb Vasc Biol
; 41(2): 769-782, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33267657
4.
Excessive dietary salt promotes aortic stiffness in murine renovascular hypertension.
Am J Physiol Heart Circ Physiol
; 318(5): H1346-H1355, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32302491
5.
Antagonism of Forkhead Box Subclass O Transcription Factors Elicits Loss of Soluble Guanylyl Cyclase Expression.
Mol Pharmacol
; 95(6): 629-637, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30988014
6.
Cytochrome b5 Reductase 3 Modulates Soluble Guanylate Cyclase Redox State and cGMP Signaling.
Circ Res
; 121(2): 137-148, 2017 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28584062
7.
Nitric Oxide-Independent Soluble Guanylate Cyclase Activation Improves Vascular Function and Cardiac Remodeling in Sickle Cell Disease.
Am J Respir Cell Mol Biol
; 58(5): 636-647, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29268036
8.
Targeting Pulmonary Endothelial Hemoglobin α Improves Nitric Oxide Signaling and Reverses Pulmonary Artery Endothelial Dysfunction.
Am J Respir Cell Mol Biol
; 57(6): 733-744, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28800253
9.
Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.
Arterioscler Thromb Vasc Biol
; 34(2): 331-337, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24311377
10.
Hemin and iron increase synthesis and trigger export of xanthine oxidoreductase from hepatocytes to the circulation.
Redox Biol
; 67: 102866, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37703667
11.
Release of hepatic xanthine oxidase (XO) to the circulation is protective in intravascular hemolytic crisis.
Redox Biol
; 62: 102636, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36906950
12.
CYB5R3 in type II alveolar epithelial cells protects against lung fibrosis by suppressing TGF-ß1 signaling.
JCI Insight
; 8(5)2023 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36749633
13.
Nrf2 Activation With CDDO-Methyl Promotes Beneficial and Deleterious Clinical Effects in Transgenic Mice With Sickle Cell Anemia.
Front Pharmacol
; 13: 880834, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35620281
14.
Angiotensin II augments renal vascular smooth muscle soluble GC expression via an AT1 receptor-forkhead box subclass O transcription factor signalling axis.
Br J Pharmacol
; 179(11): 2490-2504, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33963547
15.
Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death.
J Clin Invest
; 132(18)2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36106636
16.
H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity.
Dev Cell
; 56(19): 2765-2782.e10, 2021 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34582749
17.
Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation.
Redox Biol
; 47: 102166, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34656824
18.
Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus.
JCI Insight
; 5(1)2020 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31941842
19.
Loss of smooth muscle CYB5R3 amplifies angiotensin II-induced hypertension by increasing sGC heme oxidation.
JCI Insight
; 4(19)2019 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31487266
20.
Smooth muscle cytochrome b5 reductase 3 deficiency accelerates pulmonary hypertension development in sickle cell mice.
Blood Adv
; 3(23): 4104-4116, 2019 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31821458