Detalhe da pesquisa
1.
Next Generation of Fluorometric Protease Assays: 7-Nitrobenz-2-oxa-1,3-diazol-4-yl-amides (NBD-Amides) as Class-Spanning Protease Substrates.
Chemistry
; 29(50): e202301855, 2023 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37313627
2.
Thermodynamic characterization of a macrocyclic Zika virus NS2B/NS3 protease inhibitor and its acyclic analogs.
Arch Pharm (Weinheim)
; 356(4): e2200518, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36480352
3.
Inhibitory effects of 190 compounds against SARS-CoV-2 Mpr o protein: Molecular docking interactions.
Arch Pharm (Weinheim)
; 356(8): e2300207, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37255416
4.
Investigation of the Compatibility between Warheads and Peptidomimetic Sequences of Protease Inhibitors-A Comprehensive Reactivity and Selectivity Study.
Int J Mol Sci
; 24(8)2023 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108388
5.
Lead Discovery of SARS-CoV-2 Main Protease Inhibitors through Covalent Docking-Based Virtual Screening.
J Chem Inf Model
; 61(4): 2062-2073, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33784094
6.
SAR of novel benzothiazoles targeting an allosteric pocket of DENV and ZIKV NS2B/NS3 proteases.
Bioorg Med Chem
; 47: 116392, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34509861
7.
SARS-CoV-PLpro-Inhibitoren als mögliche Breitspektrum-Virostatika.
Biospektrum (Heidelb)
; 27(3): 254-256, 2021.
Artigo
em Alemão
| MEDLINE | ID: mdl-33994673
8.
Interaction of cyclic mechanical stretch and toll-like receptor 4-mediated innate immunity in rat alveolar type II cells.
Respirology
; 19(1): 67-73, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23796194
9.
Peptidyl nitroalkene inhibitors of main protease rationalized by computational and crystallographic investigations as antivirals against SARS-CoV-2.
Commun Chem
; 7(1): 15, 2024 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38238420
10.
Effects of nasal high flow on ventilation in volunteers, COPD and idiopathic pulmonary fibrosis patients.
Respiration
; 85(4): 319-25, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23128844
11.
A competition smFRET assay to study ligand-induced conformational changes of the dengue virus protease.
Protein Sci
; 32(1): e4526, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36461913
12.
Improving binding entropy by higher ligand symmetry? - A case study with human matriptase.
RSC Med Chem
; 14(5): 969-982, 2023 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37252099
13.
The effects of allosteric and competitive inhibitors on ZIKV protease conformational dynamics explored through smFRET, nanoDSF, DSF, and 19F NMR.
Eur J Med Chem
; 258: 115573, 2023 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37379675
14.
Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors.
Eur J Med Chem
; 247: 115021, 2023 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36549112
15.
Interfering with Host Proteases in SARS-CoV-2 Entry as a Promising Therapeutic Strategy.
Curr Med Chem
; 29(4): 635-665, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34042026
16.
A low-cost 3D-printable differential scanning fluorometer for protein and RNA melting experiments.
HardwareX
; 11: e00256, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35509940
17.
Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues.
ACS Chem Biol
; 17(3): 576-589, 2022 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35262340
18.
Development of Urea-Bond-Containing Michael Acceptors as Antitrypanosomal Agents Targeting Rhodesain.
ACS Med Chem Lett
; 13(7): 1083-1090, 2022 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35859868
19.
Nintedanib plus docetaxel after progression on first-line immunochemotherapy in patients with lung adenocarcinoma: Cohort C of the non-interventional study, VARGADO.
Transl Lung Cancer Res
; 11(10): 2010-2021, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-36386456
20.
Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening.
J Antibiot (Tokyo)
; 75(6): 321-332, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35440771