A Hybrid Approach Based on Deep CNN and Machine Learning Classifiers for the Tumor Segmentation and Classification in Brain MRI.

Conventional medical imaging and machine learning techniques are not perfect enough to correctly segment the brain tumor in MRI as the proper identification and segmentation of tumor borders are one of the most important criteria of tumor extraction. The existing approaches are time-consuming, incursive, and susceptible to human mistake. These drawbacks highlight the importance of developing a completely automated deep learning-based approach for segmentation and classification of brain tumors. The expedient and prompt segmentation and classification of a brain tumor are critical for accurate clinical diagnosis and adequately treatment. As a result, deep learning-based brain tumor segmentation and classification algorithms are extensively employed. In the deep learning-based brain tumor segmentation and classification technique, the CNN model has an excellent brain segmentation and classification effect. In this work, an integrated and hybrid approach based on deep convolutional neural network and machine learning classifiers is proposed for the accurate segmentation and classification of brain MRI tumor. A CNN is proposed in the first stage to learn the feature map from image space of brain MRI into the tumor marker region. In the second step, a faster region-based CNN is developed for the localization of tumor region followed by region proposal network (RPN). In the last step, a deep convolutional neural network and machine learning classifiers are incorporated in series in order to further refine the segmentation and classification process to obtain more accurate results and findings. The proposed model's performance is assessed based on evaluation metrics extensively used in medical image processing. The experimental results validate that the proposed deep CNN and SVM-RBF classifier achieved an accuracy of 98.3% and a dice similarity coefficient (DSC) of 97.8% on the task of classifying brain tumors as gliomas, meningioma, or pituitary using brain dataset-1, while on Figshare dataset, it achieved an accuracy of 98.0% and a DSC of 97.1% on classifying brain tumors as gliomas, meningioma, or pituitary. The segmentation and classification results demonstrate that the proposed model outperforms state-of-the-art techniques by a significant margin.

Beyond The Pleasure Principle - Fatal Cardiac Arrhythmias After Ingestion Of An Herbal Medication.

There is increasing popularity in the use of herbal medicine for different ailments as these natural products are considered safer than conventional medicines; however, their use in dosage exceeding prescribed limits can result in serious toxic side effects. We present a case of a 63-year old male who presented with complaints of restlessness, nausea, vomiting and tingling sensation on his body and ECG evidence of bi-directional ventricular tachycardia. On interrogation, it was revealed that the patient had self-prepared and consumed large quantity of an herbal medication (containing toxic aconite roots) as therapy for erectile dysfunction resulting in a fatal outcome.

Image-based state-of-the-art techniques for the identification and classification of brain diseases: a review.

Detection and classification methods have a vital and important role in identifying brain diseases. Timely detection and classification of brain diseases enable an accurate identification and effective management of brain impairment. Brain disorders are commonly most spreadable diseases and the diagnosing process is time-consuming and highly expensive. There is an utmost need to develop effective and advantageous methods for brain diseases detection and characterization. Magnetic resonance imaging (MRI), computed tomography (CT), and other various brain imaging scans are used to identify different brain diseases and disorders. Brain imaging scans are the efficient tool to understand the anatomical changes in brain in fast and accurate manner. These different brain imaging scans used with segmentation techniques and along with machine learning and deep learning techniques give maximum accuracy and efficiency. This paper focuses on different conventional approaches, machine learning and deep learning techniques used for the detection, and classification of brain diseases and abnormalities. This paper also summarizes the research gap and problems in the existing techniques used for detection and classification of brain disorders. Comparison and evaluation of different machine learning and deep learning techniques in terms of efficiency and accuracy are also highlighted in this paper. Furthermore, different brain diseases like leukoariaosis, Alzheimer's, Parkinson's, and Wilson's disorder are studied in the scope of machine learning and deep learning techniques.