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Gan To Kagaku Ryoho ; 38(4): 607-11, 2011 Apr.
Artigo em Japonês | MEDLINE | ID: mdl-21498989

RESUMO

A survey on chemotherapy-induced nausea, vomiting and food intake was conducted on 126 outpatients receiving chemotherapy during a days from February 1 to February 12, 2010 in our hospital. Responses were obtained from 66 outpatients. In the acute phase, 11%of the patients developed nausea. In the late phase, 35%patients developed nausea. The development of nausea was significantly increased in the late phase, compared to the acute phase(p=0. 0008). Though nobody developed vomiting in the acute phase, 3% of the patients developed vomiting in the late phase. For food intake, in the acute phase, nobody showed a"reduced amount of diet", and 12% showed"not eating". In the late phase, 26% of the patients showed"reduced amount of food", and 8%"not eating". Food intake was significantly decreased in the late phase, compared in acute phase(p=0. 0001). Currently, in our hospital, steroids and/or 5-HT3 antagonists are given for antiemetic therapy, but the effect is not enough. We should add other antiemetics, which act in the late phase.


Assuntos
Antineoplásicos/efeitos adversos , Regulação do Apetite/efeitos dos fármacos , Náusea/induzido quimicamente , Neoplasias/tratamento farmacológico , Pacientes Ambulatoriais , Vômito/induzido quimicamente , Adulto , Idoso , Idoso de 80 Anos ou mais , Antineoplásicos/uso terapêutico , Humanos , Pessoa de Meia-Idade , Inquéritos e Questionários
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