Detalhe da pesquisa
1.
Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses.
Mol Cell
; 81(21): 4467-4480.e7, 2021 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34687604
2.
Interfering with nucleotide excision by the coronavirus 3'-to-5' exoribonuclease.
Nucleic Acids Res
; 51(1): 315-336, 2023 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36546762
3.
Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q.
Proc Natl Acad Sci U S A
; 118(10)2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33658373
4.
Recent progress and structural analyses of domain-selective BET inhibitors.
Med Res Rev
; 43(4): 972-1018, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36971240
5.
4-Isocyanoindole-2'-deoxyribonucleoside (4ICIN): An Isomorphic Indole Nucleoside Suitable for Inverse Electron Demand Diels-Alder Reactions.
Tetrahedron Lett
; 1322023 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38009110
6.
Expanding Catch and Release DNA Decoy (CRDD) Technology with Pyrimidine Mimics.
Chemistry
; 28(58): e202201355, 2022 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35849314
7.
Function-Oriented and Modular (+/-)-cis-Pseudoguaianolide Synthesis: Discovery of New Nrf2 Activators and NF-κB Inhibitors.
Chemistry
; 27(17): 5564-5571, 2021 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33502811
8.
Selective N-Terminal BET Bromodomain Inhibitors by Targeting Non-Conserved Residues and Structured Water Displacement*.
Angew Chem Int Ed Engl
; 60(3): 1220-1226, 2021 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32975004
9.
Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA.
Chembiochem
; 21(7): 1028-1035, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31633265
10.
Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues.
Biochemistry
; 58(5): 391-400, 2019 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30418757
11.
Determinants of Oligonucleotide Selectivity of APOBEC3B.
J Chem Inf Model
; 59(5): 2264-2273, 2019 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30130104
12.
SN-38 Conjugated Gold Nanoparticles Activated by Ewing Sarcoma Specific mRNAs Exhibit In Vitro and In Vivo Efficacy.
Bioconjug Chem
; 29(4): 1111-1118, 2018 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-29412642
13.
Immunodetection of human topoisomerase I-DNA covalent complexes.
Nucleic Acids Res
; 44(6): 2816-26, 2016 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26917015
14.
Synthesis of a peptide-universal nucleotide antigen: towards next-generation antibodies to detect topoisomerase I-DNA covalent complexes.
Org Biomol Chem
; 14(17): 4103-9, 2016 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27113574
15.
Rapid, Microwave Accelerated Synthesis of [1,2,4]Triazolo[3,4-b][1,3,4]oxadiazoles from 4-Acylamino-1,2,4-Triazoles.
Tetrahedron Lett
; 57(36): 4056-4060, 2016 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28138199
16.
Parthenolide prodrug LC-1 slows growth of intracranial glioma.
Bioorg Med Chem Lett
; 25(12): 2493-5, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25978958
17.
Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues.
Bioorg Med Chem
; 23(15): 4737-4745, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26088334
18.
Development of Allosteric Small Molecule APOBEC3B Inhibitors from In Silico Screening.
bioRxiv
; 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38712210
19.
Synthesis and photophysical characterization of fluorescent indole nucleoside analogues.
RSC Adv
; 13(24): 16369-16376, 2023 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37266506
20.
Development of Allosteric NIK Ligands from Fragment-Based NMR Screening.
ACS Med Chem Lett
; 14(12): 1815-1820, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38116406