Pesquisa | Portal de Pesquisa da BVS

1.

Nephrocytes Remove Microbiota-Derived Peptidoglycan from Systemic Circulation to Maintain Immune Homeostasis.

Troha, Katia; Nagy, Peter; Pivovar, Andrew; Lazzaro, Brian P; Hartley, Paul S; Buchon, Nicolas.

Immunity ; 51(4): 625-637.e3, 2019 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-31564469

2.

Exploring the relevance of NUP93 variants in steroid-resistant nephrotic syndrome using next generation sequencing and a fly kidney model.

Bierzynska, Agnieszka; Bull, Katherine; Miellet, Sara; Dean, Philip; Neal, Chris; Colby, Elizabeth; McCarthy, Hugh J; Hegde, Shivaram; Sinha, Manish D; Bugarin Diz, Carmen; Stirrups, Kathleen; Megy, Karyn; Mapeta, Rutendo; Penkett, Chris; Marsh, Sarah; Forrester, Natalie; Afzal, Maryam; Stark, Hannah; BioResource, Nihr; Williams, Maggie; Welsh, Gavin I; Koziell, Ania B; Hartley, Paul S; Saleem, Moin A.

Pediatr Nephrol ; 37(11): 2643-2656, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-35211795

3.

Mice housed in groups of 4-6 exhibit a diurnal surge in their platelet count.

Hartley, Paul S.

Platelets ; 24(5): 412-4, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-22812592

4.

The diurnal tick-tockery of platelet biology.

Hartley, Paul S.

Platelets ; 23(2): 157-60, 2012.

Artigo em Inglês | MEDLINE | ID: mdl-21806497

5.

Insect nephrocyte function is regulated by a store operated calcium entry mechanism controlling endocytosis and Amnionless turnover.

Sivakumar, Shruthi; Miellet, Sara; Clarke, Charlotte; Hartley, Paul S.

J Insect Physiol ; 143: 104453, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36341969

6.

Piezo buffers mechanical stress via modulation of intracellular Ca²⁺ handling in the Drosophila heart.

Zechini, Luigi; Camilleri-Brennan, Julian; Walsh, Jonathan; Beaven, Robin; Moran, Oscar; Hartley, Paul S; Diaz, Mary; Denholm, Barry.

Front Physiol ; 13: 1003999, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36187790

7.

Modeling Podocyte Biology Using Drosophila Nephrocytes.

Hartley, Paul S; Coward, Richard J.

Methods Mol Biol ; 2067: 11-24, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-31701442

8.

Timed feeding of mice modulates light-entrained circadian rhythms of reticulated platelet abundance and plasma thrombopoietin and affects gene expression in megakaryocytes.

Hartley, Paul S; Sheward, John; Scholefield, Emma; French, Karen; Horn, Jacqueline M; Holmes, Megan C; Harmar, Anthony J.

Br J Haematol ; 146(2): 185-92, 2009 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-19438469

9.

As time flies by: Investigating cardiac aging in the short-lived Drosophila model.

Blice-Baum, Anna C; Guida, Maria Clara; Hartley, Paul S; Adams, Peter D; Bodmer, Rolf; Cammarato, Anthony.

Biochim Biophys Acta Mol Basis Dis ; 1865(7): 1831-1844, 2019 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-30496794

10.

The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila.

Vaughan, Leigh; Marley, Richard; Miellet, Sara; Hartley, Paul S.

Exp Gerontol ; 109: 59-66, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-29032244

11.

Drosophila pericardial nephrocyte ultrastructure changes during ageing.

Psathaki, Olympia-Ekaterini; Dehnen, Lena; Hartley, Paul S; Paululat, Achim.

Mech Ageing Dev ; 173: 9-20, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29702130

12.

Platelet senescence and death.

Hartley, Paul S.

Clin Lab ; 53(3-4): 157-66, 2007.

Artigo em Inglês | MEDLINE | ID: mdl-17447652

13.

The death of human platelets during incubation in citrated plasma involves shedding of CD42b and aggregation of dead platelets.

Hartley, Paul S; Savill, John; Brown, Simon B.

Thromb Haemost ; 95(1): 100-6, 2006 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-16543968

14.

SPARC-Dependent Cardiomyopathy in Drosophila.

Hartley, Paul S; Motamedchaboki, Khatereh; Bodmer, Rolf; Ocorr, Karen.

Circ Cardiovasc Genet ; 9(2): 119-29, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26839388

15.

Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes.

Ivy, Jessica R; Drechsler, Maik; Catterson, James H; Bodmer, Rolf; Ocorr, Karen; Paululat, Achim; Hartley, Paul S.

PLoS One ; 10(8): e0134620, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26301956

16.

Fermitins, the orthologs of mammalian Kindlins, regulate the development of a functional cardiac syncytium in Drosophila melanogaster.

Catterson, James H; Heck, Margarete M S; Hartley, Paul S.

PLoS One ; 8(5): e62958, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23690969

17.

Dietary modulation of Drosophila sleep-wake behaviour.

Catterson, James H; Knowles-Barley, Seymour; James, Katherine; Heck, Margarete M S; Harmar, Anthony J; Hartley, Paul S.

PLoS One ; 5(8): e12062, 2010 Aug 10.

Artigo em Inglês | MEDLINE | ID: mdl-20706579

18.

Hypoglycaemia predisposes platelets to death by affecting calcium homeostasis and mitochondrial integrity.

Hartley, Paul S; Savill, John S; Brown, Simon B.

Platelets ; 18(2): 103-12, 2007 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-17365858

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Nephrocytes Remove Microbiota-Derived Peptidoglycan from Systemic Circulation to Maintain Immune Homeostasis.

Exploring the relevance of NUP93 variants in steroid-resistant nephrotic syndrome using next generation sequencing and a fly kidney model.

Mice housed in groups of 4-6 exhibit a diurnal surge in their platelet count.

The diurnal tick-tockery of platelet biology.

Insect nephrocyte function is regulated by a store operated calcium entry mechanism controlling endocytosis and Amnionless turnover.

Piezo buffers mechanical stress via modulation of intracellular Ca²⁺ handling in the Drosophila heart.

Modeling Podocyte Biology Using Drosophila Nephrocytes.

Timed feeding of mice modulates light-entrained circadian rhythms of reticulated platelet abundance and plasma thrombopoietin and affects gene expression in megakaryocytes.

As time flies by: Investigating cardiac aging in the short-lived Drosophila model.

The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila.

Drosophila pericardial nephrocyte ultrastructure changes during ageing.

Platelet senescence and death.

The death of human platelets during incubation in citrated plasma involves shedding of CD42b and aggregation of dead platelets.

SPARC-Dependent Cardiomyopathy in Drosophila.

Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes.

Fermitins, the orthologs of mammalian Kindlins, regulate the development of a functional cardiac syncytium in Drosophila melanogaster.

Dietary modulation of Drosophila sleep-wake behaviour.

Hypoglycaemia predisposes platelets to death by affecting calcium homeostasis and mitochondrial integrity.