Detalhe da pesquisa
1.
Physiological Functions of the Volume-Regulated Anion Channel VRAC/LRRC8 and the Proton-Activated Chloride Channel ASOR/TMEM206.
Handb Exp Pharmacol
; 283: 181-218, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-37468723
2.
Structural deficits in key domains of Shank2 lead to alterations in postsynaptic nanoclusters and to a neurodevelopmental disorder in humans.
Mol Psychiatry
; 2022 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36450866
3.
Ion Channels and Transporters in Muscle Cell Differentiation.
Int J Mol Sci
; 22(24)2021 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34948411
4.
Truncating mutations in SHANK3 associated with global developmental delay interfere with nuclear ß-catenin signaling.
J Neurochem
; 155(3): 250-263, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32202324
5.
The Shank/ProSAP N-Terminal (SPN) Domain of Shank3 Regulates Targeting to Postsynaptic Sites and Postsynaptic Signaling.
Mol Neurobiol
; 61(2): 693-706, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37656313
6.
Mutations affecting the N-terminal domains of SHANK3 point to different pathomechanisms in neurodevelopmental disorders.
Sci Rep
; 12(1): 902, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35042901
7.
Autism-associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses.
Elife
; 102021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33945465
8.
SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling.
Curr Biol
; 31(22): 4956-4970.e9, 2021 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34610274
9.
Targeting of δ-catenin to postsynaptic sites through interaction with the Shank3 N-terminus.
Mol Autism
; 11(1): 85, 2020 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33115499
10.
Germline AGO2 mutations impair RNA interference and human neurological development.
Nat Commun
; 11(1): 5797, 2020 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199684
11.
Functional Relevance of Missense Mutations Affecting the N-Terminal Part of Shank3 Found in Autistic Patients.
Front Mol Neurosci
; 11: 268, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131675