Detalhe da pesquisa
2.
Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis.
Proc Natl Acad Sci U S A
; 119(3)2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35017302
3.
RNA localization and co-translational interactions control RAB13 GTPase function and cell migration.
EMBO J
; 39(21): e104958, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32946136
4.
Corticosteroid sensitization drives opioid addiction.
Mol Psychiatry
; 27(5): 2492-2501, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35296810
5.
Antisense oligonucleotide-mediated correction of CFTR splicing improves chloride secretion in cystic fibrosis patient-derived bronchial epithelial cells.
Nucleic Acids Res
; 48(13): 7454-7467, 2020 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32520327
6.
Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction.
Nucleic Acids Res
; 48(9): 5065-5080, 2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32249312
7.
Identification of SRSF10 as a regulator of SMN2 ISS-N1.
Hum Mutat
; 42(3): 246-260, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33300159
8.
Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson's disease patient fibroblasts.
Hum Mol Genet
; 28(19): 3232-3243, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31261377
9.
Direct Delivery of Antisense Oligonucleotides to the Middle and Inner Ear Improves Hearing and Balance in Usher Mice.
Mol Ther
; 28(12): 2662-2676, 2020 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32818431
10.
A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD.
Hum Mol Genet
; 27(19): 3313-3324, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29931260
11.
Rescue of peripheral vestibular function in Usher syndrome mice using a splice-switching antisense oligonucleotide.
Hum Mol Genet
; 26(18): 3482-3494, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28633508
12.
Targeting Amyloid-ß Precursor Protein, APP, Splicing with Antisense Oligonucleotides Reduces Toxic Amyloid-ß Production.
Mol Ther
; 26(6): 1539-1551, 2018 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29628304
13.
Induction of antagonistic soluble decoy receptor tyrosine kinases by intronic polyA activation.
Mol Cell
; 43(6): 927-39, 2011 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21925381
14.
Splice-switching antisense oligonucleotides as therapeutic drugs.
Nucleic Acids Res
; 44(14): 6549-63, 2016 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27288447
15.
Antisense oligonucleotides delivered to the amniotic cavity in utero modulate gene expression in the postnatal mouse.
Nucleic Acids Res
; 44(20): 9519-9529, 2016 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27683224
16.
Drosha promotes splicing of a pre-microRNA-like alternative exon.
PLoS Genet
; 10(5): e1004312, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24786770
17.
SCRIB and PUF60 are primary drivers of the multisystemic phenotypes of the 8q24.3 copy-number variant.
Am J Hum Genet
; 93(5): 798-811, 2013 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24140112
18.
Biogenesis of mammalian microRNAs by a non-canonical processing pathway.
Nucleic Acids Res
; 40(10): 4626-40, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22270084
19.
MicroRNAs are exported from malignant cells in customized particles.
Nucleic Acids Res
; 40(18): 9125-38, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22772984
20.
Ensemble analysis of primary microRNA structure reveals an extensive capacity to deform near the Drosha cleavage site.
Biochemistry
; 52(5): 795-807, 2013 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23305493