Detalhe da pesquisa
1.
The impact of chronic kidney disease and dialysis therapy on outcomes of elderly patients with hip fractures: A systematic review and meta-analysis.
Scott Med J
; 67(4): 144-156, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35862029
2.
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation.
Nature
; 477(7365): 477-81, 2011 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21892191
3.
Multigram-scale Synthesis of Enantiopure 3,3-Difluoroproline.
Tetrahedron Lett
; 57(50): 5658-5660, 2016 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28584384
4.
Antiobesity Effect of a Small Molecule Repressor of RORγ.
Mol Pharmacol
; 88(1): 48-56, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25904554
5.
The discovery of indole full agonists of the neurotensin receptor 1 (NTSR1).
Bioorg Med Chem Lett
; 24(16): 3974-8, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24997685
6.
Synthesis and SAR of novel isoxazoles as potent c-jun N-terminal kinase (JNK) inhibitors.
Bioorg Med Chem Lett
; 24(1): 161-4, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24332487
7.
Yiwei Xiaoyu granules for treatment of chronic atrophic gastritis with deficiency syndrome of the spleen and stomach.
World J Clin Cases
; 12(13): 2201-2209, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38808353
8.
Efficacy of Shu-yi-ning-chang decoction on IBS-D: Modulating Nr4a3 pathway to reduce visceral hypersensitivity.
PLoS One
; 19(4): e0299376, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38630738
9.
Angiotensin-converting enzyme inhibitors provide a protective effect on hypoxia-induced injury in human coronary artery endothelial cells via Nrf2 signaling and PLVAP.
Clin Hemorheol Microcirc
; 2024 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38339922
10.
Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker.
Bioorg Med Chem
; 21(21): 6642-9, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23993674
11.
Structure-Activity Relationship and Biological Investigation of a REV-ERBα-Selective Agonist SR-29065 (34) for Autoimmune Disorders.
J Med Chem
; 66(21): 14815-14823, 2023 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37888788
12.
Small molecule tertiary amines as agonists of the nuclear hormone receptor Rev-erbα.
Bioorg Med Chem Lett
; 22(13): 4413-7, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22633688
13.
Synthesis and SAR of novel quinazolines as potent and brain-penetrant c-jun N-terminal kinase (JNK) inhibitors.
Bioorg Med Chem Lett
; 21(6): 1719-23, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21316221
14.
Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors.
Bioorg Med Chem Lett
; 21(9): 2732-5, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21185177
15.
Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement.
J Mol Biol
; 433(22): 167258, 2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547329
16.
Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv
; 7(5)2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33571132
17.
Characterization of dasatinib and its structural analogs as CYP3A4 mechanism-based inactivators and the proposed bioactivation pathways.
Drug Metab Dispos
; 37(6): 1242-50, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19282395
18.
Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors.
Bioorg Med Chem Lett
; 19(12): 3344-7, 2009 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19433357
19.
Partial agonists activate PPARgamma using a helix 12 independent mechanism.
Structure
; 15(10): 1258-71, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17937915
20.
Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways.
ACS Chem Biol
; 14(5): 1051-1062, 2019 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30951276