Detalhe da pesquisa
1.
Impaired Adipogenesis and Dysfunctional Adipose Tissue in Human Hypertrophic Obesity.
Physiol Rev
; 98(4): 1911-1941, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30067159
2.
Adipocyte precursor cells from first degree relatives of type 2 diabetic patients feature changes in hsa-mir-23a-5p, -193a-5p, and -193b-5p and insulin-like growth factor 2 expression.
FASEB J
; 35(4): e21357, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33710685
3.
Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity.
Diabetologia
; 61(2): 369-380, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29067487
4.
Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice.
Am J Physiol Endocrinol Metab
; 313(4): E450-E462, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28655716
5.
WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.
Proc Natl Acad Sci U S A
; 110(7): 2563-8, 2013 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23359679
6.
The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT.
J Biol Chem
; 289(10): 6899-6907, 2014 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24451367
7.
Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver.
PLoS One
; 16(2): e0247300, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33606810
8.
Impact of the Uncoupling Protein 1 on Cardiovascular Risk in Patients with Rheumatoid Arthritis.
Cells
; 10(5)2021 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34067093
9.
The Novel Adipokine Gremlin 1 Antagonizes Insulin Action and Is Increased in Type 2 Diabetes and NAFLD/NASH.
Diabetes
; 69(3): 331-341, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31882566
10.
Altered PTPRD DNA methylation associates with restricted adipogenesis in healthy first-degree relatives of Type 2 diabetes subjects.
Epigenomics
; 12(10): 873-888, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32483983
11.
BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice.
Mol Metab
; 32: 15-26, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32029225
12.
Inflammation and impaired adipogenesis in hypertrophic obesity in man.
Am J Physiol Endocrinol Metab
; 297(5): E999-E1003, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19622783
13.
CCN5/WISP2 and metabolic diseases.
J Cell Commun Signal
; 12(1): 309-318, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29247377
14.
c-erbB2-induced disruption of matrix adhesion and morphogenesis reveals a novel role for protein kinase B as a negative regulator of alpha(2)beta(1) integrin function.
Mol Biol Cell
; 13(8): 2894-908, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12181354
15.
BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue.
Cell Rep
; 20(5): 1038-1049, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28768190
16.
Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance.
Sci Rep
; 7: 43515, 2017 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28240264
17.
Insulin resistance and impaired adipogenesis.
Trends Endocrinol Metab
; 26(4): 193-200, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25703677
18.
BMP4 and BMP Antagonists Regulate Human White and Beige Adipogenesis.
Diabetes
; 64(5): 1670-81, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605802
19.
Restricted adipogenesis in hypertrophic obesity: the role of WISP2, WNT, and BMP4.
Diabetes
; 62(9): 2997-3004, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23970518
20.
Inflamed adipose tissue, insulin resistance and vascular injury.
Diabetes Metab Res Rev
; 24(8): 595-603, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18756581