Detalhe da pesquisa
1.
Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.
Int J Cancer
; 136(9): 2078-90, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25302649
2.
Important roles of brain-specific carnitine palmitoyltransferase and ceramide metabolism in leptin hypothalamic control of feeding.
Proc Natl Acad Sci U S A
; 108(23): 9691-6, 2011 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21593415
3.
Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition.
J Biol Chem
; 287(25): 21224-32, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22539351
4.
Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake.
Am J Physiol Endocrinol Metab
; 305(3): E336-47, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23736540
5.
Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity.
Chirality
; 25(5): 281-7, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23620264
6.
Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol.
J Lipid Res
; 53(10): 2046-2056, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22847177
7.
Cornelia de Lange syndrome with NIPBL mutation and mosaic Turner syndrome in the same individual.
BMC Med Genet
; 13: 43, 2012 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22676896
8.
Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation.
Hepatology
; 53(3): 821-32, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21319201
9.
Characterization of splice variants of the genes encoding human mitochondrial HMG-CoA lyase and HMG-CoA synthase, the main enzymes of the ketogenesis pathway.
Mol Biol Rep
; 39(4): 4777-85, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21952825
10.
Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1a.
Am J Physiol Regul Integr Comp Physiol
; 301(1): R209-17, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21508288
11.
Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control.
J Biol Chem
; 284(34): 22840-52, 2009 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-19553674
12.
Mutations and variants in the cohesion factor genes NIPBL, SMC1A, and SMC3 in a cohort of 30 unrelated patients with Cornelia de Lange syndrome.
Am J Med Genet A
; 152A(4): 924-9, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20358602
13.
Differential HMG-CoA lyase expression in human tissues provides clues about 3-hydroxy-3-methylglutaric aciduria.
J Inherit Metab Dis
; 33(4): 405-10, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20532825
14.
Ten novel HMGCL mutations in 24 patients of different origin with 3-hydroxy-3-methyl-glutaric aciduria.
Hum Mutat
; 30(3): E520-9, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19177531
15.
Novel role of FATP1 in mitochondrial fatty acid oxidation in skeletal muscle cells.
J Lipid Res
; 50(9): 1789-99, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19429947
16.
Modulating aroma compounds during wine fermentation by manipulating carnitine acetyltransferases in Saccharomyces cerevisiae.
FEMS Microbiol Lett
; 267(2): 159-66, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17156120
17.
(-)-UB006: A new fatty acid synthase inhibitor and cytotoxic agent without anorexic side effects.
Eur J Med Chem
; 131: 207-221, 2017 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28324785
18.
Alteration of the malonyl-CoA/carnitine palmitoyltransferase I interaction in the beta-cell impairs glucose-induced insulin secretion.
Diabetes
; 54(2): 462-71, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15677504
19.
Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal.
Biochem J
; 379(Pt 3): 777-84, 2004 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14711372
20.
Regulation of substrate oxidation preferences in muscle by the peptide hormone adropin.
Diabetes
; 63(10): 3242-52, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24848071