Detalhe da pesquisa
1.
Activation of human STING by a molecular glue-like compound.
Nat Chem Biol
; 20(3): 365-372, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37828400
2.
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Nat Chem Biol
; 16(1): 50-59, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31819276
3.
Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Nat Chem Biol
; 16(4): 479, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32139909
4.
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical MatterâCompounds with Novel Mechanisms from High-Throughput Screening Profiles.
ACS Chem Biol
; 19(4): 938-952, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38565185
5.
DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.
Nat Commun
; 15(1): 275, 2024 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177131
6.
DRUG-seq Provides Unbiased Biological Activity Readouts for Neuroscience Drug Discovery.
ACS Chem Biol
; 17(6): 1401-1414, 2022 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508359
7.
An activity-based probe for high-throughput measurements of triacylglycerol lipases.
Anal Biochem
; 414(2): 254-60, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21397586
8.
Applying the pro-drug approach to afford highly bioavailable antagonists of P2Y(14).
Bioorg Med Chem Lett
; 21(14): 4366-8, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21689930
9.
The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14.
Bioorg Med Chem Lett
; 21(10): 2836-9, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21507640
10.
Synthesis and SAR of pyrimidine-based, non-nucleotide P2Y14 receptor antagonists.
Bioorg Med Chem Lett
; 21(10): 2832-5, 2011 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21507642
11.
An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity.
Cell Chem Biol
; 28(6): 802-812.e6, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33333026
12.
Tricyclic imidazole antagonists of the Neuropeptide S Receptor.
Bioorg Med Chem Lett
; 20(15): 4704-8, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20615693
13.
Synthesis and evaluation of a new series of Neuropeptide S receptor antagonists.
Bioorg Med Chem Lett
; 20(15): 4700-3, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20510609
14.
Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists.
Bioorg Med Chem Lett
; 19(19): 5741-5, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19713110
15.
DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery.
Nat Commun
; 9(1): 4307, 2018 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333485
16.
An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity.
Cell Chem Biol
; 28(4): 583, 2021 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33861956
17.
The human Burkitt lymphoma cell line Namalwa represents a homogenous cell system characterized by high levels of Toll-like receptor 9 and activation by CpG oligonucleotides.
J Immunol Methods
; 300(1-2): 93-9, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15894327
18.
Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation.
PLoS One
; 10(6): e0127498, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26098886
19.
Resorufin butyrate as a soluble and monomeric high-throughput substrate for a triglyceride lipase.
J Biomol Screen
; 17(2): 245-51, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21956174
20.
Discovery of novel P2Y14 agonist and antagonist using conventional and nonconventional methods.
J Biomol Screen
; 16(9): 1098-105, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21821827