Detalhe da pesquisa
1.
Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis.
Brain
; 146(9): 3770-3782, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36883643
2.
Insights into the identification of a molecular signature for amyotrophic lateral sclerosis exploiting integrated microRNA profiling of iPSC-derived motor neurons and exosomes.
Cell Mol Life Sci
; 79(3): 189, 2022 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35286466
3.
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Alzheimers Dement
; 19(4): 1245-1259, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993441
4.
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS.
Acta Neuropathol
; 144(3): 465-488, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895140
5.
A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.
Acta Neuropathol
; 135(3): 427-443, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29302778
6.
Hdac6 deletion delays disease progression in the SOD1G93A mouse model of ALS.
Hum Mol Genet
; 22(9): 1783-90, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23364049
7.
Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis.
Brain
; 136(Pt 2): 471-82, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23378219
8.
Neuronal overexpression of IP3 receptor 2 is detrimental in mutant SOD1 mice.
Biochem Biophys Res Commun
; 429(3-4): 210-3, 2012 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23131553
9.
HDAC3 Inhibition Stimulates Myelination in a CMT1A Mouse Model.
Mol Neurobiol
; 59(6): 3414-3430, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320455
10.
AAV9-mediated gene delivery of MCT1 to oligodendrocytes does not provide a therapeutic benefit in a mouse model of ALS.
Mol Ther Methods Clin Dev
; 20: 508-519, 2021 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33614825
11.
Beta1-adrenoceptor expression in rat anterior pituitary gonadotrophs and in mouse alphaT3-1 and LbetaT2 gonadotrophic cell lines.
Endocrinology
; 149(5): 2313-24, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18202120
12.
Molecular Dissection of FUS Points at Synergistic Effect of Low-Complexity Domains in Toxicity.
Cell Rep
; 24(3): 529-537.e4, 2018 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30021151
13.
Genetic variant in the HSPB1 promoter region impairs the HSP27 stress response.
Hum Mutat
; 28(8): 830, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17623484
14.
The adult pituitary contains a cell population displaying stem/progenitor cell and early embryonic characteristics.
Endocrinology
; 146(9): 3985-98, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15932930
15.
VEGF protects motor neurons against excitotoxicity by upregulation of GluR2.
Neurobiol Aging
; 31(12): 2185-91, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19185395
16.
Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish.
Hum Mol Genet
; 16(19): 2359-65, 2007 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17636250
17.
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity.
Proc Natl Acad Sci U S A
; 104(37): 14825-30, 2007 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-17804792