Detalhe da pesquisa
1.
Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation.
Cell
; 165(7): 1644-1657, 2016 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27238018
2.
CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy.
Proc Natl Acad Sci U S A
; 119(40): e2203936119, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36161947
3.
A genome-wide RNAi screen for modifiers of the circadian clock in human cells.
Cell
; 139(1): 199-210, 2009 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-19765810
4.
Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc Natl Acad Sci U S A
; 118(26)2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34172584
5.
Development of a novel PET ligand, [11C]GO289 targeting CK2 expressed in the brain.
Bioorg Med Chem Lett
; 90: 129327, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37187253
6.
Phosphorylation of RNA Polymerase II by CDKC;2 Maintains the Arabidopsis Circadian Clock Period.
Plant Cell Physiol
; 63(4): 450-462, 2022 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35086143
7.
Isoform-selective regulation of mammalian cryptochromes.
Nat Chem Biol
; 16(6): 676-685, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32231341
8.
Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock.
Proc Natl Acad Sci U S A
; 116(23): 11528-11536, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31097584
9.
Photopharmacological Manipulation of Mammalian CRY1 for Regulation of the Circadian Clock.
J Am Chem Soc
; 143(4): 2078-2087, 2021 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33464888
10.
Reductive stability evaluation of 6-azopurine photoswitches for the regulation of CKIα activity and circadian rhythms.
Org Biomol Chem
; 19(10): 2312-2321, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33634812
11.
Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.
Proc Natl Acad Sci U S A
; 115(52): E12305-E12312, 2018 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30530698
12.
A N-terminally deleted form of the CK2α' catalytic subunit is sufficient to support cell viability.
Biochem Biophys Res Commun
; 531(3): 409-415, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32800562
13.
Chemical Synthesis of Atomically Tailored SUMO E2 Conjugating Enzymes for the Formation of Covalently Linked SUMO-E2-E3 Ligase Ternary Complexes.
J Am Chem Soc
; 141(37): 14742-14751, 2019 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31436980
14.
Controlling the Circadian Clock with High Temporal Resolution through Photodosing.
J Am Chem Soc
; 141(40): 15784-15791, 2019 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31509406
15.
Conformational dynamics of human protein kinase CK2α and its effect on function and inhibition.
Proteins
; 86(3): 344-353, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29243286
16.
Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock.
Proc Natl Acad Sci U S A
; 111(5): 2040-5, 2014 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24449901
17.
C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock.
Angew Chem Int Ed Engl
; 54(24): 7193-7, 2015 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25960183
18.
Real-time in vivo monitoring of circadian E-box enhancer activity: a robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock.
Dev Biol
; 380(2): 259-73, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23665472
19.
Light-dependent and circadian clock-regulated activation of sterol regulatory element-binding protein, X-box-binding protein 1, and heat shock factor pathways.
Proc Natl Acad Sci U S A
; 108(12): 4864-9, 2011 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21383147
20.
High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase.
PLoS Biol
; 8(12): e1000559, 2010 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21179498