Detalhe da pesquisa
1.
A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis.
N Engl J Med
; 390(9): 783-794, 2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38381664
2.
Immunopathogenesis of Primary Biliary Cholangitis, Primary Sclerosing Cholangitis and Autoimmune Hepatitis: Themes and Concepts.
Gastroenterology
; 166(6): 995-1019, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38342195
3.
Identifying a therapeutic window of opportunity for people living with primary sclerosing cholangitis: Embryology and the overlap of inflammatory bowel disease with immune mediated liver injury.
Hepatology
; 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38743006
4.
Treatment response and clinical event-free survival in autoimmune hepatitis: a Canadian multicentre cohort study.
J Hepatol
; 2024 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38527524
5.
Single-cell, single-nucleus, and spatial transcriptomics characterization of the immunological landscape in the healthy and PSC human liver.
J Hepatol
; 80(5): 730-743, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38199298
6.
Seladelpar treatment reduces IL-31 and pruritus in patients with primary biliary cholangitis.
Hepatology
; 2023 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38117036
7.
Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study.
Hepatology
; 78(2): 397-415, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37386786
8.
Primary sclerosing cholangitis and overlap features of autoimmune hepatitis: A coming of age or an age-ist problem?
J Hepatol
; 79(2): 567-575, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36870613
9.
GLIMMER: A Randomized Phase 2b Dose-Ranging Trial of Linerixibat in Primary Biliary Cholangitis Patients With Pruritus.
Clin Gastroenterol Hepatol
; 21(7): 1902-1912.e13, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-36343847
10.
Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.
Gastroenterology
; 163(6): 1630-1642.e3, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36150526
11.
Ursodeoxycholic Acid Treatment-Induced GLOBE Score Changes Are Associated With Liver Transplantation-Free Survival in Patients With Primary Biliary Cholangitis.
Am J Gastroenterol
; 118(7): 1196-1203, 2023 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36621963
12.
Ethnicity, disease severity, and survival in Canadian patients with primary biliary cholangitis.
Hepatology
; 76(2): 303-316, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35220609
13.
Optimizing therapy in primary biliary cholangitis: Alkaline phosphatase at six months identifies one-year non-responders and predicts survival.
Liver Int
; 43(7): 1497-1506, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37157905
14.
The human liver microenvironment shapes the homing and function of CD4+ T-cell populations.
Gut
; 71(7): 1399-1411, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34548339
15.
Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis.
Gut
; 71(5): 1006-1019, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34001645
16.
Systematic review of response criteria and endpoints in autoimmune hepatitis by the International Autoimmune Hepatitis Group.
J Hepatol
; 76(4): 841-849, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35066089
17.
A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis.
J Hepatol
; 77(2): 353-364, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35367282
18.
A Randomized, Dose-Finding, Proof-of-Concept Study of Berberine Ursodeoxycholate in Patients With Primary Sclerosing Cholangitis.
Am J Gastroenterol
; 117(11): 1805-1815, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36327436
19.
Evaluation of quantitative MRCP (MRCP+) for risk stratification of primary sclerosing cholangitis: comparison with morphological MRCP, MR elastography, and biochemical risk scores.
Eur Radiol
; 32(1): 67-77, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34231037
20.
Trends in liver transplantation for autoimmune liver diseases: a Canadian study.
Can J Surg
; 65(5): E665-E674, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36223935