Detalhe da pesquisa
1.
Structure and dynamics of pteridine reductase 1: the key phenomena relevant to enzyme function and drug design.
Eur Biophys J
; 52(6-7): 521-532, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37608196
2.
Comparative mapping of on-targets and off-targets for the discovery of anti-trypanosomatid folate pathway inhibitors.
Biochim Biophys Acta Gen Subj
; 1861(12): 3215-3230, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28939533
3.
Application of a simple quantum chemical approach to ligand fragment scoring for Trypanosoma brucei pteridine reductase 1 inhibition.
J Comput Aided Mol Des
; 31(8): 715-728, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28688090
4.
Wellbeing Impact Study of High-Speed 2 (WISH2): Protocol for a mixed-methods examination of the impact of major transport infrastructure development on mental health and wellbeing.
PLoS One
; 19(2): e0298701, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38422089
5.
Evaluation of an organisational-level monetary incentive to promote the health and wellbeing of workers in small and medium-sized enterprises: A mixed-methods cluster randomised controlled trial.
PLOS Glob Public Health
; 3(7): e0001381, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37410723
6.
An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration.
Nat Commun
; 14(1): 619, 2023 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36739436
7.
Anti-trypanosomatid structure-based drug design - lessons learned from targeting the folate pathway.
Expert Opin Drug Discov
; 17(9): 1029-1045, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36073204
8.
Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism.
Pharmaceuticals (Basel)
; 15(5)2022 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35631380
9.
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.
J Med Chem
; 65(13): 9011-9033, 2022 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35675511
10.
Allostery in Its Many Disguises: From Theory to Applications.
Structure
; 27(4): 566-578, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30744993
11.
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform.
SLAS Discov
; 24(3): 346-361, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30784368
12.
Understanding mental health in the research environment: A Rapid Evidence Assessment.
Rand Health Q
; 7(3): 2, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29607246
13.
Review of Computerised Cognitive Behavioural Therapies: Products and Outcomes for People with Mental Health Needs.
Rand Health Q
; 6(4): 12, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28983435
14.
Psychological Wellbeing and Work: Improving Service Provision and Outcomes.
Rand Health Q
; 4(1): 9, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-28083323