Detalhe da pesquisa
1.
Cytotoxic Effects of the Schweinfurthin Analog 5'-Methylschweinfurthin G in Malignant Plasma Cells.
Pharmacology
; 107(9-10): 510-523, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35810739
2.
Multi-dimensional analysis identifies an immune signature predicting response to decitabine treatment in elderly patients with AML.
Br J Haematol
; 188(5): 674-684, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31573077
3.
The Dopamine D2 Receptor Contributes to the Spheroid Formation Behavior of U87 Glioblastoma Cells.
Pharmacology
; 105(1-2): 19-27, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31645049
4.
Inhibiting geranylgeranyl diphosphate synthesis reduces nuclear androgen receptor signaling and neuroendocrine differentiation in prostate cancer cell models.
Prostate
; 79(1): 21-30, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30106164
5.
Cancer and the Dopamine D2 Receptor: A Pharmacological Perspective.
J Pharmacol Exp Ther
; 370(1): 111-126, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31000578
6.
Brain cholesterol metabolism and Parkinson's disease.
Mov Disord
; 34(3): 386-395, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30681742
7.
A phase I clinical trial of avelumab in combination with decitabine as first line treatment of unfit patients with acute myeloid leukemia.
Am J Hematol
; 96(2): E46-E50, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33146922
8.
Phase I and pharmacokinetic study of the novel anthracycline derivative 5-imino-13-deoxydoxorubicin (GPX-150) in patients with advanced solid tumors.
Invest New Drugs
; 33(3): 594-602, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25698442
9.
Primary Cutaneous Polymorphic EBV-Associated Posttransplant Lymphoproliferative Disorder After a Renal Transplant and Review of the Literature.
Am J Dermatopathol
; 37(10): 790-4, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25747810
10.
Synthesis of isoprenoid bisphosphonate ethers through C-P bond formations: Potential inhibitors of geranylgeranyl diphosphate synthase.
Beilstein J Org Chem
; 10: 1645-50, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25161722
11.
Quantitative determination of isopentenyl diphosphate in cultured mammalian cells.
Anal Biochem
; 433(1): 36-42, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23000003
12.
Functional evaluation of a fluorescent schweinfurthin: mechanism of cytotoxicity and intracellular quantification.
Mol Pharmacol
; 82(1): 9-16, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22461663
13.
RNAseq reveals extensive metabolic disruptions in the sensitive SF-295 cell line treated with schweinfurthins.
Sci Rep
; 12(1): 359, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35013404
14.
Therapeutic Potential of 5'-Methylschweinfurthin G in Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma.
Viruses
; 14(9)2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36146655
15.
Post-transplant cyclophosphamide alters immune signatures and leads to impaired T cell reconstitution in allogeneic hematopoietic stem cell transplant.
J Hematol Oncol
; 15(1): 64, 2022 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35590334
16.
A novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitro.
J Lipid Res
; 52(11): 1957-64, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21903868
17.
The effects of direct inhibition of geranylgeranyl pyrophosphate synthase on osteoblast differentiation.
J Cell Biochem
; 112(6): 1506-13, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21503955
18.
Bisphosphonates induce autophagy by depleting geranylgeranyl diphosphate.
J Pharmacol Exp Ther
; 337(2): 540-6, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21335425
19.
Geranylgeranyl diphosphate depletion inhibits breast cancer cell migration.
Invest New Drugs
; 29(5): 912-20, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20480384
20.
Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium-dependent, non-D2 receptor-dependent, manner.
Pharmacol Res Perspect
; 9(3): e00689, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34003586