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Nanotechnology ; 21(18): 185102, 2010 May 07.
Artigo em Inglês | MEDLINE | ID: mdl-20378952

RESUMO

In this work we report the synthesis, characterization and application of silver vanadate nanowires decorated with silver nanoparticles as a novel antibacterial agent. These hybrid materials were synthesized by a precipitation reaction of ammonium vanadate and silver nitrate followed by hydrothermal treatment. The silver vanadate nanowires have lengths of the order of microns and diameters around 60 nm. The silver nanoparticles decorating the nanowires present a diameter distribution varying from 1 to 20 nm. The influence of the pH of the reaction medium on the chemical structure and morphology of silver vanadates was studied and we found that synthesis performed at pH 5.5-6.0 led to silver vanadate nanowires with a higher morphological yield. The antimicrobial activity of these materials was evaluated against three strains of Staphylococcus aureus and very promising results were found. The minimum growth inhibiting concentration value against a MRSA strain was found to be ten folds lower than for the antibiotic oxacillin.


Assuntos
Antibacterianos/química , Nanopartículas Metálicas/química , Nanofios/química , Prata/química , Prata/farmacologia , Vanadatos/química , Vanadatos/farmacologia , Antibacterianos/farmacologia , Cristalografia por Raios X , Concentração de Íons de Hidrogênio , Testes de Sensibilidade Microbiana , Microscopia Eletrônica de Varredura , Tamanho da Partícula , Espectroscopia de Infravermelho com Transformada de Fourier , Staphylococcus aureus/efeitos dos fármacos
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